Supercritical CO2 extraction of raw propolis and its dry ethanolic extract

Detalhes bibliográficos
Autor(a) principal: Paviani,L. C.
Data de Publicação: 2012
Outros Autores: Saito,E., Dariva,C., Marcucci,M. C., Sánchez-Camargo,A. P., Cabral,F. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Chemical Engineering
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322012000200005
Resumo: Three types of propolis extract were prepared and analyzed with respect to their global extraction yields and with respect to the concentration of the following markers: 3,5-diprenyl-4-hydroxycinnamic acid; 3-prenyl-4-hydroxycinnamic acid; 4-hydroxycinnamic acid and 4-methoxy-3,5,7-trihydroxyflavone. The extract EEP (ethanolic extract of propolis) was obtained by the conventional method from raw propolis using ethanol as solvent. The extracts (SFE) were obtained by supercritical solvent extraction from the raw propolis using supercritical carbon dioxide (sc-CO2), with and without the addition of ethanol as a co-solvent. The fractionated supercritical extracts (FSCE) were obtained by fractionation (extract and raffinate) of the dry EEP with sc-CO2. EEP yields of 39.5% were obtained and maximum global extraction yields were 7.3% for SFE with no co-solvent, 51% for SFE with 15% ethanol and 18% for the FSCE extract fraction. The concentrations of the markers in the different extracts differed as a function of the operational parameters, indicating that the addition of co-solvent and the selectivity of sc-CO2 could be manipulated so as to obtain extracts with the yields and concentrations of interest.
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spelling Supercritical CO2 extraction of raw propolis and its dry ethanolic extractBrazilian propolisSupercritical extractionArtepillin CPhenolic compoundsThree types of propolis extract were prepared and analyzed with respect to their global extraction yields and with respect to the concentration of the following markers: 3,5-diprenyl-4-hydroxycinnamic acid; 3-prenyl-4-hydroxycinnamic acid; 4-hydroxycinnamic acid and 4-methoxy-3,5,7-trihydroxyflavone. The extract EEP (ethanolic extract of propolis) was obtained by the conventional method from raw propolis using ethanol as solvent. The extracts (SFE) were obtained by supercritical solvent extraction from the raw propolis using supercritical carbon dioxide (sc-CO2), with and without the addition of ethanol as a co-solvent. The fractionated supercritical extracts (FSCE) were obtained by fractionation (extract and raffinate) of the dry EEP with sc-CO2. EEP yields of 39.5% were obtained and maximum global extraction yields were 7.3% for SFE with no co-solvent, 51% for SFE with 15% ethanol and 18% for the FSCE extract fraction. The concentrations of the markers in the different extracts differed as a function of the operational parameters, indicating that the addition of co-solvent and the selectivity of sc-CO2 could be manipulated so as to obtain extracts with the yields and concentrations of interest.Brazilian Society of Chemical Engineering2012-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322012000200005Brazilian Journal of Chemical Engineering v.29 n.2 2012reponame:Brazilian Journal of Chemical Engineeringinstname:Associação Brasileira de Engenharia Química (ABEQ)instacron:ABEQ10.1590/S0104-66322012000200005info:eu-repo/semantics/openAccessPaviani,L. C.Saito,E.Dariva,C.Marcucci,M. C.Sánchez-Camargo,A. P.Cabral,F. A.eng2012-06-21T00:00:00Zoai:scielo:S0104-66322012000200005Revistahttps://www.scielo.br/j/bjce/https://old.scielo.br/oai/scielo-oai.phprgiudici@usp.br||rgiudici@usp.br1678-43830104-6632opendoar:2012-06-21T00:00Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ)false
dc.title.none.fl_str_mv Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
title Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
spellingShingle Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
Paviani,L. C.
Brazilian propolis
Supercritical extraction
Artepillin C
Phenolic compounds
title_short Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
title_full Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
title_fullStr Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
title_full_unstemmed Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
title_sort Supercritical CO2 extraction of raw propolis and its dry ethanolic extract
author Paviani,L. C.
author_facet Paviani,L. C.
Saito,E.
Dariva,C.
Marcucci,M. C.
Sánchez-Camargo,A. P.
Cabral,F. A.
author_role author
author2 Saito,E.
Dariva,C.
Marcucci,M. C.
Sánchez-Camargo,A. P.
Cabral,F. A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Paviani,L. C.
Saito,E.
Dariva,C.
Marcucci,M. C.
Sánchez-Camargo,A. P.
Cabral,F. A.
dc.subject.por.fl_str_mv Brazilian propolis
Supercritical extraction
Artepillin C
Phenolic compounds
topic Brazilian propolis
Supercritical extraction
Artepillin C
Phenolic compounds
description Three types of propolis extract were prepared and analyzed with respect to their global extraction yields and with respect to the concentration of the following markers: 3,5-diprenyl-4-hydroxycinnamic acid; 3-prenyl-4-hydroxycinnamic acid; 4-hydroxycinnamic acid and 4-methoxy-3,5,7-trihydroxyflavone. The extract EEP (ethanolic extract of propolis) was obtained by the conventional method from raw propolis using ethanol as solvent. The extracts (SFE) were obtained by supercritical solvent extraction from the raw propolis using supercritical carbon dioxide (sc-CO2), with and without the addition of ethanol as a co-solvent. The fractionated supercritical extracts (FSCE) were obtained by fractionation (extract and raffinate) of the dry EEP with sc-CO2. EEP yields of 39.5% were obtained and maximum global extraction yields were 7.3% for SFE with no co-solvent, 51% for SFE with 15% ethanol and 18% for the FSCE extract fraction. The concentrations of the markers in the different extracts differed as a function of the operational parameters, indicating that the addition of co-solvent and the selectivity of sc-CO2 could be manipulated so as to obtain extracts with the yields and concentrations of interest.
publishDate 2012
dc.date.none.fl_str_mv 2012-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322012000200005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322012000200005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0104-66322012000200005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Chemical Engineering
publisher.none.fl_str_mv Brazilian Society of Chemical Engineering
dc.source.none.fl_str_mv Brazilian Journal of Chemical Engineering v.29 n.2 2012
reponame:Brazilian Journal of Chemical Engineering
instname:Associação Brasileira de Engenharia Química (ABEQ)
instacron:ABEQ
instname_str Associação Brasileira de Engenharia Química (ABEQ)
instacron_str ABEQ
institution ABEQ
reponame_str Brazilian Journal of Chemical Engineering
collection Brazilian Journal of Chemical Engineering
repository.name.fl_str_mv Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ)
repository.mail.fl_str_mv rgiudici@usp.br||rgiudici@usp.br
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