Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates

Detalhes bibliográficos
Autor(a) principal: Mattos,Luiz Carlos de
Data de Publicação: 2016
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de hematologia e hemoterapia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331
Resumo: ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates.
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spelling Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydratesHisto-blood groupsABO systemLewis systemCarbohydrate antigenGlycosyltransferasesABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates.Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular2016-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331Revista Brasileira de Hematologia e Hemoterapia v.38 n.4 2016reponame:Revista brasileira de hematologia e hemoterapia (Online)instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)instacron:ABHHTC10.1016/j.bjhh.2016.07.005info:eu-repo/semantics/openAccessMattos,Luiz Carlos deeng2017-03-30T00:00:00Zoai:scielo:S1516-84842016000400331Revistahttp://www.rbhh.org/pt/archivo/https://old.scielo.br/oai/scielo-oai.phpsbhh@terra.com.br||secretaria@rbhh.org1806-08701516-8484opendoar:2017-03-30T00:00Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)false
dc.title.none.fl_str_mv Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
title Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
spellingShingle Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
Mattos,Luiz Carlos de
Histo-blood groups
ABO system
Lewis system
Carbohydrate antigen
Glycosyltransferases
title_short Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
title_full Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
title_fullStr Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
title_full_unstemmed Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
title_sort Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
author Mattos,Luiz Carlos de
author_facet Mattos,Luiz Carlos de
author_role author
dc.contributor.author.fl_str_mv Mattos,Luiz Carlos de
dc.subject.por.fl_str_mv Histo-blood groups
ABO system
Lewis system
Carbohydrate antigen
Glycosyltransferases
topic Histo-blood groups
ABO system
Lewis system
Carbohydrate antigen
Glycosyltransferases
description ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842016000400331
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjhh.2016.07.005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
dc.source.none.fl_str_mv Revista Brasileira de Hematologia e Hemoterapia v.38 n.4 2016
reponame:Revista brasileira de hematologia e hemoterapia (Online)
instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron:ABHHTC
instname_str Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron_str ABHHTC
institution ABHHTC
reponame_str Revista brasileira de hematologia e hemoterapia (Online)
collection Revista brasileira de hematologia e hemoterapia (Online)
repository.name.fl_str_mv Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
repository.mail.fl_str_mv sbhh@terra.com.br||secretaria@rbhh.org
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