In Vivo Evaluation of Hydroxyapatite Foams

Detalhes bibliográficos
Autor(a) principal: Sepulveda,P.
Data de Publicação: 2002
Outros Autores: Bressiani,A.H., Bressiani,J.C., Meseguer,L., König Jr,B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392002000300006
Resumo: Porous hydroxyapatite manufactured by foaming of aqueous ceramic suspensions and setting via gelcasting of organic monomers was tested for in vivo biocompatibility in rabbit tibia for a period of 8 weeks. The foams provide tortous frameworks and large interconnected pores that support cell attachment and organisation into 3D arrays to form new tissue. The HA foam implants were progressively filled with mature new bone tissue and osteoid after the implanted period, confirming the high osteoconductive potential and high biocompatibility of HA and the suitability of foam network in providing good osteointegration. No immune or inflammatory reactions were detected.
id ABMABCABPOL-1_3674b9198243c09e11126d190420a126
oai_identifier_str oai:scielo:S1516-14392002000300006
network_acronym_str ABMABCABPOL-1
network_name_str Materials research (São Carlos. Online)
repository_id_str
spelling In Vivo Evaluation of Hydroxyapatite Foamsporous hydroxyapatitegelcasting of foamsbiocompatibilityrabbit tibiabone graftsPorous hydroxyapatite manufactured by foaming of aqueous ceramic suspensions and setting via gelcasting of organic monomers was tested for in vivo biocompatibility in rabbit tibia for a period of 8 weeks. The foams provide tortous frameworks and large interconnected pores that support cell attachment and organisation into 3D arrays to form new tissue. The HA foam implants were progressively filled with mature new bone tissue and osteoid after the implanted period, confirming the high osteoconductive potential and high biocompatibility of HA and the suitability of foam network in providing good osteointegration. No immune or inflammatory reactions were detected.ABM, ABC, ABPol2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392002000300006Materials Research v.5 n.3 2002reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/S1516-14392002000300006info:eu-repo/semantics/openAccessSepulveda,P.Bressiani,A.H.Bressiani,J.C.Meseguer,L.König Jr,B.eng2002-11-08T00:00:00Zoai:scielo:S1516-14392002000300006Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2002-11-08T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv In Vivo Evaluation of Hydroxyapatite Foams
title In Vivo Evaluation of Hydroxyapatite Foams
spellingShingle In Vivo Evaluation of Hydroxyapatite Foams
Sepulveda,P.
porous hydroxyapatite
gelcasting of foams
biocompatibility
rabbit tibia
bone grafts
title_short In Vivo Evaluation of Hydroxyapatite Foams
title_full In Vivo Evaluation of Hydroxyapatite Foams
title_fullStr In Vivo Evaluation of Hydroxyapatite Foams
title_full_unstemmed In Vivo Evaluation of Hydroxyapatite Foams
title_sort In Vivo Evaluation of Hydroxyapatite Foams
author Sepulveda,P.
author_facet Sepulveda,P.
Bressiani,A.H.
Bressiani,J.C.
Meseguer,L.
König Jr,B.
author_role author
author2 Bressiani,A.H.
Bressiani,J.C.
Meseguer,L.
König Jr,B.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sepulveda,P.
Bressiani,A.H.
Bressiani,J.C.
Meseguer,L.
König Jr,B.
dc.subject.por.fl_str_mv porous hydroxyapatite
gelcasting of foams
biocompatibility
rabbit tibia
bone grafts
topic porous hydroxyapatite
gelcasting of foams
biocompatibility
rabbit tibia
bone grafts
description Porous hydroxyapatite manufactured by foaming of aqueous ceramic suspensions and setting via gelcasting of organic monomers was tested for in vivo biocompatibility in rabbit tibia for a period of 8 weeks. The foams provide tortous frameworks and large interconnected pores that support cell attachment and organisation into 3D arrays to form new tissue. The HA foam implants were progressively filled with mature new bone tissue and osteoid after the implanted period, confirming the high osteoconductive potential and high biocompatibility of HA and the suitability of foam network in providing good osteointegration. No immune or inflammatory reactions were detected.
publishDate 2002
dc.date.none.fl_str_mv 2002-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392002000300006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392002000300006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-14392002000300006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.5 n.3 2002
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
_version_ 1754212656975183872