HPMA and HEMA copolymer bead interactions with eukaryotic cells

Detalhes bibliográficos
Autor(a) principal: Vianna-Soares,Cristina D.
Data de Publicação: 2004
Outros Autores: Cherng-Ju,Kim, Ciftci,Kadriye, Borenstein,Michael R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392004000300016
Resumo: Two different hydrophilic acrylate beads were prepared via aqueous suspension polymerization. Beads produced of a hydroxypropyl methacrylate (HPMA) and ethyleneglycol methacrylate (EDMA) copolymer were obtained using a polyvinyl alcohol suspending medium. Copolymers of 2hydroxyethyl methacrylate (HEMA), methyl methacrylate (MMA) and ethyleneglycol methacrylate (EDMA) beads were obtained using magnesium hydroxide as the suspending agent. Following characterization by scanning electron microscopy (SEM), nitrogen sorption analysis (NSA) and mercury intrusion porosimetry (MIP), the beads were cultured with monkey fibroblasts (COS7) to evaluate their ability to support cell growth, attachment and adhesion. Cell growth behavior onto small HPMA/EDMA copolymer beads and large HEMA/MMA/EDMA copolymer beads is evaluated regarding their hidrophilicity/hidrophobicity and surface roughness.
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spelling HPMA and HEMA copolymer bead interactions with eukaryotic cellscell attachmentadhesionhydrophilic/hydrophobic beadsacrylate polymerTwo different hydrophilic acrylate beads were prepared via aqueous suspension polymerization. Beads produced of a hydroxypropyl methacrylate (HPMA) and ethyleneglycol methacrylate (EDMA) copolymer were obtained using a polyvinyl alcohol suspending medium. Copolymers of 2hydroxyethyl methacrylate (HEMA), methyl methacrylate (MMA) and ethyleneglycol methacrylate (EDMA) beads were obtained using magnesium hydroxide as the suspending agent. Following characterization by scanning electron microscopy (SEM), nitrogen sorption analysis (NSA) and mercury intrusion porosimetry (MIP), the beads were cultured with monkey fibroblasts (COS7) to evaluate their ability to support cell growth, attachment and adhesion. Cell growth behavior onto small HPMA/EDMA copolymer beads and large HEMA/MMA/EDMA copolymer beads is evaluated regarding their hidrophilicity/hidrophobicity and surface roughness.ABM, ABC, ABPol2004-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392004000300016Materials Research v.7 n.3 2004reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/S1516-14392004000300016info:eu-repo/semantics/openAccessVianna-Soares,Cristina D.Cherng-Ju,KimCiftci,KadriyeBorenstein,Michael R.eng2004-08-13T00:00:00Zoai:scielo:S1516-14392004000300016Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2004-08-13T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv HPMA and HEMA copolymer bead interactions with eukaryotic cells
title HPMA and HEMA copolymer bead interactions with eukaryotic cells
spellingShingle HPMA and HEMA copolymer bead interactions with eukaryotic cells
Vianna-Soares,Cristina D.
cell attachment
adhesion
hydrophilic/hydrophobic beads
acrylate polymer
title_short HPMA and HEMA copolymer bead interactions with eukaryotic cells
title_full HPMA and HEMA copolymer bead interactions with eukaryotic cells
title_fullStr HPMA and HEMA copolymer bead interactions with eukaryotic cells
title_full_unstemmed HPMA and HEMA copolymer bead interactions with eukaryotic cells
title_sort HPMA and HEMA copolymer bead interactions with eukaryotic cells
author Vianna-Soares,Cristina D.
author_facet Vianna-Soares,Cristina D.
Cherng-Ju,Kim
Ciftci,Kadriye
Borenstein,Michael R.
author_role author
author2 Cherng-Ju,Kim
Ciftci,Kadriye
Borenstein,Michael R.
author2_role author
author
author
dc.contributor.author.fl_str_mv Vianna-Soares,Cristina D.
Cherng-Ju,Kim
Ciftci,Kadriye
Borenstein,Michael R.
dc.subject.por.fl_str_mv cell attachment
adhesion
hydrophilic/hydrophobic beads
acrylate polymer
topic cell attachment
adhesion
hydrophilic/hydrophobic beads
acrylate polymer
description Two different hydrophilic acrylate beads were prepared via aqueous suspension polymerization. Beads produced of a hydroxypropyl methacrylate (HPMA) and ethyleneglycol methacrylate (EDMA) copolymer were obtained using a polyvinyl alcohol suspending medium. Copolymers of 2hydroxyethyl methacrylate (HEMA), methyl methacrylate (MMA) and ethyleneglycol methacrylate (EDMA) beads were obtained using magnesium hydroxide as the suspending agent. Following characterization by scanning electron microscopy (SEM), nitrogen sorption analysis (NSA) and mercury intrusion porosimetry (MIP), the beads were cultured with monkey fibroblasts (COS7) to evaluate their ability to support cell growth, attachment and adhesion. Cell growth behavior onto small HPMA/EDMA copolymer beads and large HEMA/MMA/EDMA copolymer beads is evaluated regarding their hidrophilicity/hidrophobicity and surface roughness.
publishDate 2004
dc.date.none.fl_str_mv 2004-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392004000300016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392004000300016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-14392004000300016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.7 n.3 2004
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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