Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol

Detalhes bibliográficos
Autor(a) principal: Peres,Matheus Ruffo
Data de Publicação: 2021
Outros Autores: Pastrello,Bruna, Sambrano,Júlio Ricardo, Morgon,Nelson Henrique, de Souza,Aguinaldo Robinson, Ximenes,Valdecir Farias
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000700211
Resumo: Abstract Titanium dioxide (TiO2) and zinc oxide (ZnO) are among the most used catalysts in photodegradation. Paracetamol and salicylic acid are widely used as pharmaceutical drugs. We found that paracetamol is less susceptible to photodegradation compared to salicylic acid. From a chemical perspective, this was not expected since paracetamol is more vulnerable to chemical oxidation. Aiming the comprehension of this phenomenon, studies were performed comparing the efficiency of photodegradation of paracetamol versus salicylic acid and acetophenone versus 4-aminoacetophenone. The presence of amino/amide group decreased the efficiency of degradation significantly. It was also found that salicylic acid improved the degradation of paracetamol when both compounds were present in the reaction medium. The lower efficiency of photodegradation of the amino-based compounds seems to be related to the deactivation of the excited states of the TiO2 and ZnO. Theoretical calculations at the TD-PBE0/6-311++G(3df,2p) high level were performed and corroborated our proposal.
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spelling Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of ParacetamolPhotodegradationTitanium DioxideZinc OxideParacetamolSalicylic AcidAbstract Titanium dioxide (TiO2) and zinc oxide (ZnO) are among the most used catalysts in photodegradation. Paracetamol and salicylic acid are widely used as pharmaceutical drugs. We found that paracetamol is less susceptible to photodegradation compared to salicylic acid. From a chemical perspective, this was not expected since paracetamol is more vulnerable to chemical oxidation. Aiming the comprehension of this phenomenon, studies were performed comparing the efficiency of photodegradation of paracetamol versus salicylic acid and acetophenone versus 4-aminoacetophenone. The presence of amino/amide group decreased the efficiency of degradation significantly. It was also found that salicylic acid improved the degradation of paracetamol when both compounds were present in the reaction medium. The lower efficiency of photodegradation of the amino-based compounds seems to be related to the deactivation of the excited states of the TiO2 and ZnO. Theoretical calculations at the TD-PBE0/6-311++G(3df,2p) high level were performed and corroborated our proposal.ABM, ABC, ABPol2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000700211Materials Research v.24 suppl.1 2021reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2021-0212info:eu-repo/semantics/openAccessPeres,Matheus RuffoPastrello,BrunaSambrano,Júlio RicardoMorgon,Nelson Henriquede Souza,Aguinaldo RobinsonXimenes,Valdecir Fariaseng2021-07-14T00:00:00Zoai:scielo:S1516-14392021000700211Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2021-07-14T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
title Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
spellingShingle Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
Peres,Matheus Ruffo
Photodegradation
Titanium Dioxide
Zinc Oxide
Paracetamol
Salicylic Acid
title_short Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
title_full Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
title_fullStr Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
title_full_unstemmed Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
title_sort Salicylic Acid Boosts the TiO2 and ZnO-Mediated Photodegradation of Paracetamol
author Peres,Matheus Ruffo
author_facet Peres,Matheus Ruffo
Pastrello,Bruna
Sambrano,Júlio Ricardo
Morgon,Nelson Henrique
de Souza,Aguinaldo Robinson
Ximenes,Valdecir Farias
author_role author
author2 Pastrello,Bruna
Sambrano,Júlio Ricardo
Morgon,Nelson Henrique
de Souza,Aguinaldo Robinson
Ximenes,Valdecir Farias
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Peres,Matheus Ruffo
Pastrello,Bruna
Sambrano,Júlio Ricardo
Morgon,Nelson Henrique
de Souza,Aguinaldo Robinson
Ximenes,Valdecir Farias
dc.subject.por.fl_str_mv Photodegradation
Titanium Dioxide
Zinc Oxide
Paracetamol
Salicylic Acid
topic Photodegradation
Titanium Dioxide
Zinc Oxide
Paracetamol
Salicylic Acid
description Abstract Titanium dioxide (TiO2) and zinc oxide (ZnO) are among the most used catalysts in photodegradation. Paracetamol and salicylic acid are widely used as pharmaceutical drugs. We found that paracetamol is less susceptible to photodegradation compared to salicylic acid. From a chemical perspective, this was not expected since paracetamol is more vulnerable to chemical oxidation. Aiming the comprehension of this phenomenon, studies were performed comparing the efficiency of photodegradation of paracetamol versus salicylic acid and acetophenone versus 4-aminoacetophenone. The presence of amino/amide group decreased the efficiency of degradation significantly. It was also found that salicylic acid improved the degradation of paracetamol when both compounds were present in the reaction medium. The lower efficiency of photodegradation of the amino-based compounds seems to be related to the deactivation of the excited states of the TiO2 and ZnO. Theoretical calculations at the TD-PBE0/6-311++G(3df,2p) high level were performed and corroborated our proposal.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000700211
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000700211
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-5373-mr-2021-0212
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.24 suppl.1 2021
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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