Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications

Detalhes bibliográficos
Autor(a) principal: Santos,André Luiz dos
Data de Publicação: 2020
Outros Autores: Duarte,Marcia A. Tomaz, Pezzin,Sérgio H., Silva,Leandro, Domingues,Juliana A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000200229
Resumo: Abstract Electrospun fibers find a number of biomedical applications, like scaffolds for tissue engineering, as polymer nanofiber mats can mimic the extracellular matrix (ECM) of the body. In this research, non-woven mats composed of poly(L-lactic acid) (PLLA) fibers were obtained by low voltage (6 kV) electrospinning of PLLA/chloroform (CL)/sodium lauryl ether sulfate (SLES) solution. Tests were performed in two different collector/capillary distances and the produced fibers were evaluated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and cell viability. The results show the formation of three dimensional mats composed of porous fibers created by the addition of small amounts of aqueous solution of SLES surfactant; a higher crystallinity degree for longer collector/capillary electrospun distance and positive cell proliferation.
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spelling Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applicationsEletrospinningMedium fieldTissue engineeringPLLAAbstract Electrospun fibers find a number of biomedical applications, like scaffolds for tissue engineering, as polymer nanofiber mats can mimic the extracellular matrix (ECM) of the body. In this research, non-woven mats composed of poly(L-lactic acid) (PLLA) fibers were obtained by low voltage (6 kV) electrospinning of PLLA/chloroform (CL)/sodium lauryl ether sulfate (SLES) solution. Tests were performed in two different collector/capillary distances and the produced fibers were evaluated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and cell viability. The results show the formation of three dimensional mats composed of porous fibers created by the addition of small amounts of aqueous solution of SLES surfactant; a higher crystallinity degree for longer collector/capillary electrospun distance and positive cell proliferation.ABM, ABC, ABPol2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000200229Materials Research v.23 n.2 2020reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2019-0468info:eu-repo/semantics/openAccessSantos,André Luiz dosDuarte,Marcia A. TomazPezzin,Sérgio H.Silva,LeandroDomingues,Juliana A.eng2020-07-29T00:00:00Zoai:scielo:S1516-14392020000200229Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2020-07-29T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
title Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
spellingShingle Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
Santos,André Luiz dos
Eletrospinning
Medium field
Tissue engineering
PLLA
title_short Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
title_full Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
title_fullStr Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
title_full_unstemmed Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
title_sort Preparation of porous poly (lactic acid) fibers by medium field electrospinning for tissue engineering applications
author Santos,André Luiz dos
author_facet Santos,André Luiz dos
Duarte,Marcia A. Tomaz
Pezzin,Sérgio H.
Silva,Leandro
Domingues,Juliana A.
author_role author
author2 Duarte,Marcia A. Tomaz
Pezzin,Sérgio H.
Silva,Leandro
Domingues,Juliana A.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos,André Luiz dos
Duarte,Marcia A. Tomaz
Pezzin,Sérgio H.
Silva,Leandro
Domingues,Juliana A.
dc.subject.por.fl_str_mv Eletrospinning
Medium field
Tissue engineering
PLLA
topic Eletrospinning
Medium field
Tissue engineering
PLLA
description Abstract Electrospun fibers find a number of biomedical applications, like scaffolds for tissue engineering, as polymer nanofiber mats can mimic the extracellular matrix (ECM) of the body. In this research, non-woven mats composed of poly(L-lactic acid) (PLLA) fibers were obtained by low voltage (6 kV) electrospinning of PLLA/chloroform (CL)/sodium lauryl ether sulfate (SLES) solution. Tests were performed in two different collector/capillary distances and the produced fibers were evaluated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and cell viability. The results show the formation of three dimensional mats composed of porous fibers created by the addition of small amounts of aqueous solution of SLES surfactant; a higher crystallinity degree for longer collector/capillary electrospun distance and positive cell proliferation.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000200229
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000200229
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-5373-mr-2019-0468
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.23 n.2 2020
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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