Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds

Detalhes bibliográficos
Autor(a) principal: Furuya,Daniela Camargo
Data de Publicação: 2017
Outros Autores: Costa,Silgia Aparecida da, Oliveira,Rodrigo Cardoso de, Ferraz,Humberto Gomes, Pessoa Junior,Adalberto, Costa,Sirlene Maria da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377
Resumo: The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer.
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spelling Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of ScaffoldsAlginatechitosanfiberscaffoldstissue engineeringThe main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer.ABM, ABC, ABPol2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377Materials Research v.20 n.2 2017reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2016-0509info:eu-repo/semantics/openAccessFuruya,Daniela CamargoCosta,Silgia Aparecida daOliveira,Rodrigo Cardoso deFerraz,Humberto GomesPessoa Junior,AdalbertoCosta,Sirlene Maria daeng2017-04-18T00:00:00Zoai:scielo:S1516-14392017000200377Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2017-04-18T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
title Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
spellingShingle Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
Furuya,Daniela Camargo
Alginate
chitosan
fiber
scaffolds
tissue engineering
title_short Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
title_full Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
title_fullStr Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
title_full_unstemmed Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
title_sort Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
author Furuya,Daniela Camargo
author_facet Furuya,Daniela Camargo
Costa,Silgia Aparecida da
Oliveira,Rodrigo Cardoso de
Ferraz,Humberto Gomes
Pessoa Junior,Adalberto
Costa,Sirlene Maria da
author_role author
author2 Costa,Silgia Aparecida da
Oliveira,Rodrigo Cardoso de
Ferraz,Humberto Gomes
Pessoa Junior,Adalberto
Costa,Sirlene Maria da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Furuya,Daniela Camargo
Costa,Silgia Aparecida da
Oliveira,Rodrigo Cardoso de
Ferraz,Humberto Gomes
Pessoa Junior,Adalberto
Costa,Sirlene Maria da
dc.subject.por.fl_str_mv Alginate
chitosan
fiber
scaffolds
tissue engineering
topic Alginate
chitosan
fiber
scaffolds
tissue engineering
description The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-5373-mr-2016-0509
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.20 n.2 2017
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
_version_ 1754212670574166016

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