Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Materials research (São Carlos. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377 |
Resumo: | The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer. |
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Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of ScaffoldsAlginatechitosanfiberscaffoldstissue engineeringThe main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer.ABM, ABC, ABPol2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377Materials Research v.20 n.2 2017reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2016-0509info:eu-repo/semantics/openAccessFuruya,Daniela CamargoCosta,Silgia Aparecida daOliveira,Rodrigo Cardoso deFerraz,Humberto GomesPessoa Junior,AdalbertoCosta,Sirlene Maria daeng2017-04-18T00:00:00Zoai:scielo:S1516-14392017000200377Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2017-04-18T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false |
dc.title.none.fl_str_mv |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
title |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
spellingShingle |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds Furuya,Daniela Camargo Alginate chitosan fiber scaffolds tissue engineering |
title_short |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
title_full |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
title_fullStr |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
title_full_unstemmed |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
title_sort |
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds |
author |
Furuya,Daniela Camargo |
author_facet |
Furuya,Daniela Camargo Costa,Silgia Aparecida da Oliveira,Rodrigo Cardoso de Ferraz,Humberto Gomes Pessoa Junior,Adalberto Costa,Sirlene Maria da |
author_role |
author |
author2 |
Costa,Silgia Aparecida da Oliveira,Rodrigo Cardoso de Ferraz,Humberto Gomes Pessoa Junior,Adalberto Costa,Sirlene Maria da |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Furuya,Daniela Camargo Costa,Silgia Aparecida da Oliveira,Rodrigo Cardoso de Ferraz,Humberto Gomes Pessoa Junior,Adalberto Costa,Sirlene Maria da |
dc.subject.por.fl_str_mv |
Alginate chitosan fiber scaffolds tissue engineering |
topic |
Alginate chitosan fiber scaffolds tissue engineering |
description |
The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability, degradation and biomineralization, as well as DSC/TGA thermal analysis. Tenacity values showed that use of glycerol and the interaction between alginate and chitosan as a hybrid fiber were associated with increasing tenacity values. In the swelling and weight loss study, the scaffolds containing glycerol presented lower weight loss and higher water absorption values in all scaffolds, compared to scaffolds without glycerol, indicating that glycerol acted as a stabilizer. None of the alginate, chitosan and hybrid scaffolds, with or without glycerol, decreased cell viability. On the third day of the biomineralization assay, chitosan without glycerol indicated the presence of apatite crystals. The degradation study showed that glycerol may have acted as a stabilizer. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392017000200377 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1980-5373-mr-2016-0509 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABM, ABC, ABPol |
publisher.none.fl_str_mv |
ABM, ABC, ABPol |
dc.source.none.fl_str_mv |
Materials Research v.20 n.2 2017 reponame:Materials research (São Carlos. Online) instname:Universidade Federal de São Carlos (UFSCAR) instacron:ABM ABC ABPOL |
instname_str |
Universidade Federal de São Carlos (UFSCAR) |
instacron_str |
ABM ABC ABPOL |
institution |
ABM ABC ABPOL |
reponame_str |
Materials research (São Carlos. Online) |
collection |
Materials research (São Carlos. Online) |
repository.name.fl_str_mv |
Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR) |
repository.mail.fl_str_mv |
dedz@power.ufscar.br |
_version_ |
1754212670574166016 |