Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds

Detalhes bibliográficos
Autor(a) principal: Costa,Hermes de Souza
Data de Publicação: 2007
Outros Autores: Pereira,Marivalda Magalhães, Andrade,Giovanna Ivo, Stancioli,Edel Figueiredo Barbosa, Mansur,Herman Sander
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100007
Resumo: Bone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al2O3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR.
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spelling Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffoldsscaffoldbioceramicsbiomaterialaluminazincBone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al2O3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR.ABM, ABC, ABPol2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100007Materials Research v.10 n.1 2007reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/S1516-14392007000100007info:eu-repo/semantics/openAccessCosta,Hermes de SouzaPereira,Marivalda MagalhãesAndrade,Giovanna IvoStancioli,Edel Figueiredo BarbosaMansur,Herman Sandereng2007-05-03T00:00:00Zoai:scielo:S1516-14392007000100007Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2007-05-03T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
title Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
spellingShingle Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
Costa,Hermes de Souza
scaffold
bioceramics
biomaterial
alumina
zinc
title_short Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
title_full Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
title_fullStr Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
title_full_unstemmed Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
title_sort Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds
author Costa,Hermes de Souza
author_facet Costa,Hermes de Souza
Pereira,Marivalda Magalhães
Andrade,Giovanna Ivo
Stancioli,Edel Figueiredo Barbosa
Mansur,Herman Sander
author_role author
author2 Pereira,Marivalda Magalhães
Andrade,Giovanna Ivo
Stancioli,Edel Figueiredo Barbosa
Mansur,Herman Sander
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Costa,Hermes de Souza
Pereira,Marivalda Magalhães
Andrade,Giovanna Ivo
Stancioli,Edel Figueiredo Barbosa
Mansur,Herman Sander
dc.subject.por.fl_str_mv scaffold
bioceramics
biomaterial
alumina
zinc
topic scaffold
bioceramics
biomaterial
alumina
zinc
description Bone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al2O3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000100007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-14392007000100007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.10 n.1 2007
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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