Idiopathic very late-onset cerebellar ataxia: a Brazilian case series
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100903 |
Resumo: | ABSTRACTThe authors present a Brazilian case series of eight patients with idiopathic very-late onset (mean 75.5 years old) cerebellar ataxia, featuring predominantly gait ataxia, associated with cerebellar atrophy.Method: 26 adult patients with a diagnosis of idiopathic late onset cerebellar ataxia were analyzed in a Brazilian ataxia outpatient clinic and followed regularly over 20 years. Among them, 8 elderly patients were diagnosed as probable very late onset cerebellar ataxia. These patients were evaluated with neurological, ophthalmologic and Mini-Mental Status examinations, brain MRI, and EMG.Results: 62.5% of patients were males, mean age was 81.9 years-old, and mean age of onset was 75.5 years. Gait cerebellar ataxia was observed in all patients, as well as, cerebellar atrophy on brain MRI. Mild cognitive impairment and visual loss, due to macular degeneration, were observed in 50% of cases. Chorea was concomitantly found in 3 patients.Conclusion: We believe that this condition is similar the one described by Marie-Foix-Alajouanine presenting with mild dysarthria, associated with gait ataxia, and some patients had cognitive dysfunction and chorea. |
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Idiopathic very late-onset cerebellar ataxia: a Brazilian case serieslate-onset cerebellar ataxiacerebellar atrophyidiopathic late-onset cerebellar ataxiacerebellar atrophy of Marie-Foix-AlajouanineABSTRACTThe authors present a Brazilian case series of eight patients with idiopathic very-late onset (mean 75.5 years old) cerebellar ataxia, featuring predominantly gait ataxia, associated with cerebellar atrophy.Method: 26 adult patients with a diagnosis of idiopathic late onset cerebellar ataxia were analyzed in a Brazilian ataxia outpatient clinic and followed regularly over 20 years. Among them, 8 elderly patients were diagnosed as probable very late onset cerebellar ataxia. These patients were evaluated with neurological, ophthalmologic and Mini-Mental Status examinations, brain MRI, and EMG.Results: 62.5% of patients were males, mean age was 81.9 years-old, and mean age of onset was 75.5 years. Gait cerebellar ataxia was observed in all patients, as well as, cerebellar atrophy on brain MRI. Mild cognitive impairment and visual loss, due to macular degeneration, were observed in 50% of cases. Chorea was concomitantly found in 3 patients.Conclusion: We believe that this condition is similar the one described by Marie-Foix-Alajouanine presenting with mild dysarthria, associated with gait ataxia, and some patients had cognitive dysfunction and chorea.Academia Brasileira de Neurologia - ABNEURO2015-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100903Arquivos de Neuro-Psiquiatria v.73 n.11 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150139info:eu-repo/semantics/openAccessTeive,Hélio A. G.Moscovich,MarianaMoro,AdrianaFarah,MarinaArruda,Walter O.Munhoz,Renato P.eng2015-10-22T00:00:00Zoai:scielo:S0004-282X2015001100903Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-10-22T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
title |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
spellingShingle |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series Teive,Hélio A. G. late-onset cerebellar ataxia cerebellar atrophy idiopathic late-onset cerebellar ataxia cerebellar atrophy of Marie-Foix-Alajouanine |
title_short |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
title_full |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
title_fullStr |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
title_full_unstemmed |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
title_sort |
Idiopathic very late-onset cerebellar ataxia: a Brazilian case series |
author |
Teive,Hélio A. G. |
author_facet |
Teive,Hélio A. G. Moscovich,Mariana Moro,Adriana Farah,Marina Arruda,Walter O. Munhoz,Renato P. |
author_role |
author |
author2 |
Moscovich,Mariana Moro,Adriana Farah,Marina Arruda,Walter O. Munhoz,Renato P. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Teive,Hélio A. G. Moscovich,Mariana Moro,Adriana Farah,Marina Arruda,Walter O. Munhoz,Renato P. |
dc.subject.por.fl_str_mv |
late-onset cerebellar ataxia cerebellar atrophy idiopathic late-onset cerebellar ataxia cerebellar atrophy of Marie-Foix-Alajouanine |
topic |
late-onset cerebellar ataxia cerebellar atrophy idiopathic late-onset cerebellar ataxia cerebellar atrophy of Marie-Foix-Alajouanine |
description |
ABSTRACTThe authors present a Brazilian case series of eight patients with idiopathic very-late onset (mean 75.5 years old) cerebellar ataxia, featuring predominantly gait ataxia, associated with cerebellar atrophy.Method: 26 adult patients with a diagnosis of idiopathic late onset cerebellar ataxia were analyzed in a Brazilian ataxia outpatient clinic and followed regularly over 20 years. Among them, 8 elderly patients were diagnosed as probable very late onset cerebellar ataxia. These patients were evaluated with neurological, ophthalmologic and Mini-Mental Status examinations, brain MRI, and EMG.Results: 62.5% of patients were males, mean age was 81.9 years-old, and mean age of onset was 75.5 years. Gait cerebellar ataxia was observed in all patients, as well as, cerebellar atrophy on brain MRI. Mild cognitive impairment and visual loss, due to macular degeneration, were observed in 50% of cases. Chorea was concomitantly found in 3 patients.Conclusion: We believe that this condition is similar the one described by Marie-Foix-Alajouanine presenting with mild dysarthria, associated with gait ataxia, and some patients had cognitive dysfunction and chorea. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100903 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100903 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20150139 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.73 n.11 2015 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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