Disability as a determinant of fatigue in MS patients

Detalhes bibliográficos
Autor(a) principal: Taveira,Fernanda M.
Data de Publicação: 2019
Outros Autores: Braz,Nayara F. T., Comini-Frota,Elizabeth R., Teixeira,Antônio L., Domingues,Renan B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000400248
Resumo: ABSTRACT Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue. Objectives: The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting MS with a low functional impairment. Methods: We compared inflammatory markers, respiratory pressures, disability, and quality of life in 39 relapsing-remitting MS patients with and without fatigue. Results: Patients with relapsing-remitting MS with fatigue had higher Expanded Disability Status Scale scores (p = 0.002). We observed a significant association between the results of the Guy Neurological Disability Scale, the Functional Assessment of MS Quality of Life Rating Scale and the presence of fatigue (p < 0.05). Conclusions: The degree of functional impairment is a determinant for the presence of fatigue in MS patients, but respiratory function and inflammatory markers are not.
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spelling Disability as a determinant of fatigue in MS patientsMultiple sclerosisfatigueinflammationABSTRACT Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue. Objectives: The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting MS with a low functional impairment. Methods: We compared inflammatory markers, respiratory pressures, disability, and quality of life in 39 relapsing-remitting MS patients with and without fatigue. Results: Patients with relapsing-remitting MS with fatigue had higher Expanded Disability Status Scale scores (p = 0.002). We observed a significant association between the results of the Guy Neurological Disability Scale, the Functional Assessment of MS Quality of Life Rating Scale and the presence of fatigue (p < 0.05). Conclusions: The degree of functional impairment is a determinant for the presence of fatigue in MS patients, but respiratory function and inflammatory markers are not.Academia Brasileira de Neurologia - ABNEURO2019-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000400248Arquivos de Neuro-Psiquiatria v.77 n.4 2019reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20190035info:eu-repo/semantics/openAccessTaveira,Fernanda M.Braz,Nayara F. T.Comini-Frota,Elizabeth R.Teixeira,Antônio L.Domingues,Renan B.eng2019-05-08T00:00:00Zoai:scielo:S0004-282X2019000400248Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2019-05-08T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Disability as a determinant of fatigue in MS patients
title Disability as a determinant of fatigue in MS patients
spellingShingle Disability as a determinant of fatigue in MS patients
Taveira,Fernanda M.
Multiple sclerosis
fatigue
inflammation
title_short Disability as a determinant of fatigue in MS patients
title_full Disability as a determinant of fatigue in MS patients
title_fullStr Disability as a determinant of fatigue in MS patients
title_full_unstemmed Disability as a determinant of fatigue in MS patients
title_sort Disability as a determinant of fatigue in MS patients
author Taveira,Fernanda M.
author_facet Taveira,Fernanda M.
Braz,Nayara F. T.
Comini-Frota,Elizabeth R.
Teixeira,Antônio L.
Domingues,Renan B.
author_role author
author2 Braz,Nayara F. T.
Comini-Frota,Elizabeth R.
Teixeira,Antônio L.
Domingues,Renan B.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Taveira,Fernanda M.
Braz,Nayara F. T.
Comini-Frota,Elizabeth R.
Teixeira,Antônio L.
Domingues,Renan B.
dc.subject.por.fl_str_mv Multiple sclerosis
fatigue
inflammation
topic Multiple sclerosis
fatigue
inflammation
description ABSTRACT Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue. Objectives: The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting MS with a low functional impairment. Methods: We compared inflammatory markers, respiratory pressures, disability, and quality of life in 39 relapsing-remitting MS patients with and without fatigue. Results: Patients with relapsing-remitting MS with fatigue had higher Expanded Disability Status Scale scores (p = 0.002). We observed a significant association between the results of the Guy Neurological Disability Scale, the Functional Assessment of MS Quality of Life Rating Scale and the presence of fatigue (p < 0.05). Conclusions: The degree of functional impairment is a determinant for the presence of fatigue in MS patients, but respiratory function and inflammatory markers are not.
publishDate 2019
dc.date.none.fl_str_mv 2019-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000400248
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000400248
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20190035
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.77 n.4 2019
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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