Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease
Autor(a) principal: | |
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Data de Publicação: | 1978 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006 |
Resumo: | Gastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of either type I or type II was observed in 5 of the 7 patients. Furthermore, in 2 of the 5 patients showing muscle fibre groupings, angular fibres reacting with NADH and non-specific sterase were also found. These observations strongly suggest denervation associated with reinervation. This picture often can be observed in the skeletal muscle of patients with well compensated denervatory conditions who do not show clinical evidences of denervation. |
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Arquivos de neuro-psiquiatria (Online) |
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Histological and histochemical changes of the skeletal muscle in human chronic Chagas' diseaseGastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of either type I or type II was observed in 5 of the 7 patients. Furthermore, in 2 of the 5 patients showing muscle fibre groupings, angular fibres reacting with NADH and non-specific sterase were also found. These observations strongly suggest denervation associated with reinervation. This picture often can be observed in the skeletal muscle of patients with well compensated denervatory conditions who do not show clinical evidences of denervation.Academia Brasileira de Neurologia - ABNEURO1978-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006Arquivos de Neuro-Psiquiatria v.36 n.4 1978reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1978000400006info:eu-repo/semantics/openAccessTaratuto,AnaliaPagano,M. A.Fumo,TeresaSanz,Olga P.Sica,R. E. P.eng2012-08-27T00:00:00Zoai:scielo:S0004-282X1978000400006Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2012-08-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
title |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
spellingShingle |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease Taratuto,Analia |
title_short |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
title_full |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
title_fullStr |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
title_full_unstemmed |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
title_sort |
Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
author |
Taratuto,Analia |
author_facet |
Taratuto,Analia Pagano,M. A. Fumo,Teresa Sanz,Olga P. Sica,R. E. P. |
author_role |
author |
author2 |
Pagano,M. A. Fumo,Teresa Sanz,Olga P. Sica,R. E. P. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Taratuto,Analia Pagano,M. A. Fumo,Teresa Sanz,Olga P. Sica,R. E. P. |
description |
Gastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of either type I or type II was observed in 5 of the 7 patients. Furthermore, in 2 of the 5 patients showing muscle fibre groupings, angular fibres reacting with NADH and non-specific sterase were also found. These observations strongly suggest denervation associated with reinervation. This picture often can be observed in the skeletal muscle of patients with well compensated denervatory conditions who do not show clinical evidences of denervation. |
publishDate |
1978 |
dc.date.none.fl_str_mv |
1978-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X1978000400006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.36 n.4 1978 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212744714780672 |