Endovascular thrombectomy for the treatment of acute ischemic stroke
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000100067 |
Resumo: | ABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to identify ongoing randomized controlled trials (RCTs). Method Searches for RCTs were performed in Medline/Embase, and for ongoing trials: International Clinical Trial Registry Platform, Clinicaltrials.gov and ISRCTN registry (to June 15th, 2015). Results From the eight published RCTs, five showed the superiority of treatment that includes thrombectomy compared to standard care alone. From the 13 ongoing RCTs, 3 have been halted, one has not started, one has unknown status and eight will end between 2016 - 2020. Conclusion Evidence favours a combination of the standard therapy with endovascular thrombectomy. The selection criteria however limit the number of people who can benefit. Further studies are needed to prove its cost-effectiveness. |
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Arquivos de neuro-psiquiatria (Online) |
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Endovascular thrombectomy for the treatment of acute ischemic strokestrokethrombectomysystematic reviewrandomized controlled trialABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to identify ongoing randomized controlled trials (RCTs). Method Searches for RCTs were performed in Medline/Embase, and for ongoing trials: International Clinical Trial Registry Platform, Clinicaltrials.gov and ISRCTN registry (to June 15th, 2015). Results From the eight published RCTs, five showed the superiority of treatment that includes thrombectomy compared to standard care alone. From the 13 ongoing RCTs, 3 have been halted, one has not started, one has unknown status and eight will end between 2016 - 2020. Conclusion Evidence favours a combination of the standard therapy with endovascular thrombectomy. The selection criteria however limit the number of people who can benefit. Further studies are needed to prove its cost-effectiveness.Academia Brasileira de Neurologia - ABNEURO2016-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000100067Arquivos de Neuro-Psiquiatria v.74 n.1 2016reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150182info:eu-repo/semantics/openAccessFerri,Cleusa P.Buehler,AnnaFlato,Uri Adrian PryncPuglia Junior,PauloFernandes,Jefferson G.eng2016-02-05T00:00:00Zoai:scielo:S0004-282X2016000100067Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2016-02-05T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
title |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
spellingShingle |
Endovascular thrombectomy for the treatment of acute ischemic stroke Ferri,Cleusa P. stroke thrombectomy systematic review randomized controlled trial |
title_short |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
title_full |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
title_fullStr |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
title_full_unstemmed |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
title_sort |
Endovascular thrombectomy for the treatment of acute ischemic stroke |
author |
Ferri,Cleusa P. |
author_facet |
Ferri,Cleusa P. Buehler,Anna Flato,Uri Adrian Prync Puglia Junior,Paulo Fernandes,Jefferson G. |
author_role |
author |
author2 |
Buehler,Anna Flato,Uri Adrian Prync Puglia Junior,Paulo Fernandes,Jefferson G. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferri,Cleusa P. Buehler,Anna Flato,Uri Adrian Prync Puglia Junior,Paulo Fernandes,Jefferson G. |
dc.subject.por.fl_str_mv |
stroke thrombectomy systematic review randomized controlled trial |
topic |
stroke thrombectomy systematic review randomized controlled trial |
description |
ABSTRACT Few patients benefit from the current standard treatment for acute ischemic stroke (AIS), encouraging the development of new treatments. Objective To systematically review the literature on the efficacy and/or safety of endovascular thrombectomy in AIS compared to standard treatment and to identify ongoing randomized controlled trials (RCTs). Method Searches for RCTs were performed in Medline/Embase, and for ongoing trials: International Clinical Trial Registry Platform, Clinicaltrials.gov and ISRCTN registry (to June 15th, 2015). Results From the eight published RCTs, five showed the superiority of treatment that includes thrombectomy compared to standard care alone. From the 13 ongoing RCTs, 3 have been halted, one has not started, one has unknown status and eight will end between 2016 - 2020. Conclusion Evidence favours a combination of the standard therapy with endovascular thrombectomy. The selection criteria however limit the number of people who can benefit. Further studies are needed to prove its cost-effectiveness. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000100067 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000100067 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20150182 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.74 n.1 2016 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212779656478720 |