Human neurocysticercosis: IgE in cerebrospinal fluid

Detalhes bibliográficos
Autor(a) principal: Melo,Carmen Silvia de
Data de Publicação: 1997
Outros Autores: Vaz,Adelaide José, Nakamura,Paulo Mutuko, Silva,Marcos Vinicius da, Machado,Aluízio de Barros Barreto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000100002
Resumo: The detection of IgE is technically difficult because of its reduced concentrations in serum, and even lower concentrations in cerebrospinal fluid (CSF). In the present investigation we studied 86 CSF samples using an immunoenzymatic method with an anti-IgE-alkaline phosphatase conjugate and a fluorigenic substrate. The samples were from three groups: A) 29 patients with neurocysticercosis (NC), B) 36 patients with different neurologic disorders (neurosyphilis, neurotuberculosis, meningitis, tumors, hemorrhage) and C) 21 discharged individuals who had been hospitalized for bacterial meningitis. The results obtained were: A) 0.05 to 3.00 IU/ml (0.76±0.79), B) 0.00 to 1.50 IU/ml (0.23±0.34) and C) 0.05 to 1.25 IU/ml (0.34±0.34). The present results suggest that IgE appears to play a role in the pathogeny of NC and that efforts should be made to standardize a test for the detection of specific IgE antibodies.
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spelling Human neurocysticercosis: IgE in cerebrospinal fluidneurocysticercosiscerebrospinal fluidIgEimmunoenzymatic assayThe detection of IgE is technically difficult because of its reduced concentrations in serum, and even lower concentrations in cerebrospinal fluid (CSF). In the present investigation we studied 86 CSF samples using an immunoenzymatic method with an anti-IgE-alkaline phosphatase conjugate and a fluorigenic substrate. The samples were from three groups: A) 29 patients with neurocysticercosis (NC), B) 36 patients with different neurologic disorders (neurosyphilis, neurotuberculosis, meningitis, tumors, hemorrhage) and C) 21 discharged individuals who had been hospitalized for bacterial meningitis. The results obtained were: A) 0.05 to 3.00 IU/ml (0.76±0.79), B) 0.00 to 1.50 IU/ml (0.23±0.34) and C) 0.05 to 1.25 IU/ml (0.34±0.34). The present results suggest that IgE appears to play a role in the pathogeny of NC and that efforts should be made to standardize a test for the detection of specific IgE antibodies.Academia Brasileira de Neurologia - ABNEURO1997-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000100002Arquivos de Neuro-Psiquiatria v.55 n.1 1997reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1997000100002info:eu-repo/semantics/openAccessMelo,Carmen Silvia deVaz,Adelaide JoséNakamura,Paulo MutukoSilva,Marcos Vinicius daMachado,Aluízio de Barros Barretoeng2010-11-10T00:00:00Zoai:scielo:S0004-282X1997000100002Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2010-11-10T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Human neurocysticercosis: IgE in cerebrospinal fluid
title Human neurocysticercosis: IgE in cerebrospinal fluid
spellingShingle Human neurocysticercosis: IgE in cerebrospinal fluid
Melo,Carmen Silvia de
neurocysticercosis
cerebrospinal fluid
IgE
immunoenzymatic assay
title_short Human neurocysticercosis: IgE in cerebrospinal fluid
title_full Human neurocysticercosis: IgE in cerebrospinal fluid
title_fullStr Human neurocysticercosis: IgE in cerebrospinal fluid
title_full_unstemmed Human neurocysticercosis: IgE in cerebrospinal fluid
title_sort Human neurocysticercosis: IgE in cerebrospinal fluid
author Melo,Carmen Silvia de
author_facet Melo,Carmen Silvia de
Vaz,Adelaide José
Nakamura,Paulo Mutuko
Silva,Marcos Vinicius da
Machado,Aluízio de Barros Barreto
author_role author
author2 Vaz,Adelaide José
Nakamura,Paulo Mutuko
Silva,Marcos Vinicius da
Machado,Aluízio de Barros Barreto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Melo,Carmen Silvia de
Vaz,Adelaide José
Nakamura,Paulo Mutuko
Silva,Marcos Vinicius da
Machado,Aluízio de Barros Barreto
dc.subject.por.fl_str_mv neurocysticercosis
cerebrospinal fluid
IgE
immunoenzymatic assay
topic neurocysticercosis
cerebrospinal fluid
IgE
immunoenzymatic assay
description The detection of IgE is technically difficult because of its reduced concentrations in serum, and even lower concentrations in cerebrospinal fluid (CSF). In the present investigation we studied 86 CSF samples using an immunoenzymatic method with an anti-IgE-alkaline phosphatase conjugate and a fluorigenic substrate. The samples were from three groups: A) 29 patients with neurocysticercosis (NC), B) 36 patients with different neurologic disorders (neurosyphilis, neurotuberculosis, meningitis, tumors, hemorrhage) and C) 21 discharged individuals who had been hospitalized for bacterial meningitis. The results obtained were: A) 0.05 to 3.00 IU/ml (0.76±0.79), B) 0.00 to 1.50 IU/ml (0.23±0.34) and C) 0.05 to 1.25 IU/ml (0.34±0.34). The present results suggest that IgE appears to play a role in the pathogeny of NC and that efforts should be made to standardize a test for the detection of specific IgE antibodies.
publishDate 1997
dc.date.none.fl_str_mv 1997-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000100002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1997000100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X1997000100002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.55 n.1 1997
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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