Botulinum toxin type A in refractory chronic migraine: an open-label trial

Detalhes bibliográficos
Autor(a) principal: Menezes,Carla
Data de Publicação: 2007
Outros Autores: Rodrigues,Bernardo, Magalhães,Elza, Melo,Ailton
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000400009
Resumo: Botulinum toxin type A (BT-A) has been described as an important strategy to various types of pain such as cervical dystonia, myofascial pain syndrome and headache. Although BT-A efficacy has not been proven in tension type headache, its use in migraine continues controversial. In this open trial, we evaluated the efficacy of BT-A in refractory migraine. BT-A was injected in patients diagnosed with migraine who had previously used three classes of prophylactic drugs by at least one year with no response. The most important improvement was observed within 30 days, but pain intensity and frequency of headache had been decreased until the end of three months of follow up. Side effects of BT-A were mild and self limited. We conclude that BT-A seems to be a safe and effective treatment to refractory migraine patients.
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spelling Botulinum toxin type A in refractory chronic migraine: an open-label trialbotulinum toxin type Amigrainepainrefractory painBotulinum toxin type A (BT-A) has been described as an important strategy to various types of pain such as cervical dystonia, myofascial pain syndrome and headache. Although BT-A efficacy has not been proven in tension type headache, its use in migraine continues controversial. In this open trial, we evaluated the efficacy of BT-A in refractory migraine. BT-A was injected in patients diagnosed with migraine who had previously used three classes of prophylactic drugs by at least one year with no response. The most important improvement was observed within 30 days, but pain intensity and frequency of headache had been decreased until the end of three months of follow up. Side effects of BT-A were mild and self limited. We conclude that BT-A seems to be a safe and effective treatment to refractory migraine patients.Academia Brasileira de Neurologia - ABNEURO2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000400009Arquivos de Neuro-Psiquiatria v.65 n.3a 2007reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2007000400009info:eu-repo/semantics/openAccessMenezes,CarlaRodrigues,BernardoMagalhães,ElzaMelo,Ailtoneng2007-09-10T00:00:00Zoai:scielo:S0004-282X2007000400009Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2007-09-10T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Botulinum toxin type A in refractory chronic migraine: an open-label trial
title Botulinum toxin type A in refractory chronic migraine: an open-label trial
spellingShingle Botulinum toxin type A in refractory chronic migraine: an open-label trial
Menezes,Carla
botulinum toxin type A
migraine
pain
refractory pain
title_short Botulinum toxin type A in refractory chronic migraine: an open-label trial
title_full Botulinum toxin type A in refractory chronic migraine: an open-label trial
title_fullStr Botulinum toxin type A in refractory chronic migraine: an open-label trial
title_full_unstemmed Botulinum toxin type A in refractory chronic migraine: an open-label trial
title_sort Botulinum toxin type A in refractory chronic migraine: an open-label trial
author Menezes,Carla
author_facet Menezes,Carla
Rodrigues,Bernardo
Magalhães,Elza
Melo,Ailton
author_role author
author2 Rodrigues,Bernardo
Magalhães,Elza
Melo,Ailton
author2_role author
author
author
dc.contributor.author.fl_str_mv Menezes,Carla
Rodrigues,Bernardo
Magalhães,Elza
Melo,Ailton
dc.subject.por.fl_str_mv botulinum toxin type A
migraine
pain
refractory pain
topic botulinum toxin type A
migraine
pain
refractory pain
description Botulinum toxin type A (BT-A) has been described as an important strategy to various types of pain such as cervical dystonia, myofascial pain syndrome and headache. Although BT-A efficacy has not been proven in tension type headache, its use in migraine continues controversial. In this open trial, we evaluated the efficacy of BT-A in refractory migraine. BT-A was injected in patients diagnosed with migraine who had previously used three classes of prophylactic drugs by at least one year with no response. The most important improvement was observed within 30 days, but pain intensity and frequency of headache had been decreased until the end of three months of follow up. Side effects of BT-A were mild and self limited. We conclude that BT-A seems to be a safe and effective treatment to refractory migraine patients.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000400009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000400009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2007000400009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.65 n.3a 2007
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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