Cervical dystonia: about familial and sporadic cases in 88 patients
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000200107 |
Resumo: | Cervical dystonia (CD) affects the musculature of the neck in a focal way or associated to other parts of the body. The aim of this study was to identify clinical differences between patients with dystonia patients without family history and with family history (sporadic). Eighty-eight patients with CD were recruited in a Movement Disorders Clinic between June of 2008 and June of 2009. Only patients with no etiological diagnosis were accepted for analysis. The age of onset of symptoms was later in patients with focal and segmental dystonia than in patients with generalized dystonia (p<0.001). The severity of symptoms was higher in patients with sporadic dystonia than in familial patients (p<0.01). Generalized cases were more severe in patients with a family history (p<0.01). Sporadic patients had higher levels of pain than familial cases (p<0.05). We expect soon to present the results of genetic analyzes of these patients. |
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Arquivos de neuro-psiquiatria (Online) |
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Cervical dystonia: about familial and sporadic cases in 88 patientsdystoniacervical dystoniaDYT1DYT6geneticCervical dystonia (CD) affects the musculature of the neck in a focal way or associated to other parts of the body. The aim of this study was to identify clinical differences between patients with dystonia patients without family history and with family history (sporadic). Eighty-eight patients with CD were recruited in a Movement Disorders Clinic between June of 2008 and June of 2009. Only patients with no etiological diagnosis were accepted for analysis. The age of onset of symptoms was later in patients with focal and segmental dystonia than in patients with generalized dystonia (p<0.001). The severity of symptoms was higher in patients with sporadic dystonia than in familial patients (p<0.01). Generalized cases were more severe in patients with a family history (p<0.01). Sporadic patients had higher levels of pain than familial cases (p<0.05). We expect soon to present the results of genetic analyzes of these patients.Academia Brasileira de Neurologia - ABNEURO2014-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000200107Arquivos de Neuro-Psiquiatria v.72 n.2 2014reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20130225info:eu-repo/semantics/openAccessCamargo,Carlos Henrique F.Camargos,Sarah TeixeiraBecker,NilsonMunhoz,Renato PuppiRaskin,SalmoCardoso,Francisco Eduardo C.Teive,Hélio Afonso G.eng2014-03-28T00:00:00Zoai:scielo:S0004-282X2014000200107Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2014-03-28T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Cervical dystonia: about familial and sporadic cases in 88 patients |
title |
Cervical dystonia: about familial and sporadic cases in 88 patients |
spellingShingle |
Cervical dystonia: about familial and sporadic cases in 88 patients Camargo,Carlos Henrique F. dystonia cervical dystonia DYT1 DYT6 genetic |
title_short |
Cervical dystonia: about familial and sporadic cases in 88 patients |
title_full |
Cervical dystonia: about familial and sporadic cases in 88 patients |
title_fullStr |
Cervical dystonia: about familial and sporadic cases in 88 patients |
title_full_unstemmed |
Cervical dystonia: about familial and sporadic cases in 88 patients |
title_sort |
Cervical dystonia: about familial and sporadic cases in 88 patients |
author |
Camargo,Carlos Henrique F. |
author_facet |
Camargo,Carlos Henrique F. Camargos,Sarah Teixeira Becker,Nilson Munhoz,Renato Puppi Raskin,Salmo Cardoso,Francisco Eduardo C. Teive,Hélio Afonso G. |
author_role |
author |
author2 |
Camargos,Sarah Teixeira Becker,Nilson Munhoz,Renato Puppi Raskin,Salmo Cardoso,Francisco Eduardo C. Teive,Hélio Afonso G. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Camargo,Carlos Henrique F. Camargos,Sarah Teixeira Becker,Nilson Munhoz,Renato Puppi Raskin,Salmo Cardoso,Francisco Eduardo C. Teive,Hélio Afonso G. |
dc.subject.por.fl_str_mv |
dystonia cervical dystonia DYT1 DYT6 genetic |
topic |
dystonia cervical dystonia DYT1 DYT6 genetic |
description |
Cervical dystonia (CD) affects the musculature of the neck in a focal way or associated to other parts of the body. The aim of this study was to identify clinical differences between patients with dystonia patients without family history and with family history (sporadic). Eighty-eight patients with CD were recruited in a Movement Disorders Clinic between June of 2008 and June of 2009. Only patients with no etiological diagnosis were accepted for analysis. The age of onset of symptoms was later in patients with focal and segmental dystonia than in patients with generalized dystonia (p<0.001). The severity of symptoms was higher in patients with sporadic dystonia than in familial patients (p<0.01). Generalized cases were more severe in patients with a family history (p<0.01). Sporadic patients had higher levels of pain than familial cases (p<0.05). We expect soon to present the results of genetic analyzes of these patients. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000200107 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000200107 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20130225 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.72 n.2 2014 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212775909916672 |