Features associated with the development of non-motor manifestations in Parkinson's disease

Detalhes bibliográficos
Autor(a) principal: Juri,Carlos
Data de Publicação: 2008
Outros Autores: Viviani,Paola, Chaná,Pedro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000100006
Resumo: Parkinson's disease (PD) is a neurodegenerative disorder, predominantly characterized by the presence of motor symptoms. However, the non motor manifestations (NMM) are a frequent complaint in the PD patients. There is a lack of information about the risk factors associated with the NMM in these patients. The aim of this study is to evaluate the prevalence of the more common NMM in a population of PD patients and to determine the features associated with its development. We studied 124 ambulatory PD patients. NMM were defined by the presence of neuropsychiatric manifestations, cognitive disorder, autonomic dysfunction or sleep related problems. In a multivariate analysis we found that the years of evolution of the PD and the presence of cognitive dysfunction are the risk factors for the neuropsychiatric and autonomic manifestations, whereas axial impairment is a risk factor for cognitive disorders and dyskinesias is for sleep related problems. In conclusion, this study shows that the features related to the PD progression appear as the main risk factors associated with NMM.
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spelling Features associated with the development of non-motor manifestations in Parkinson's diseaseParkinson's diseasenon motor manifestationsParkinson's disease (PD) is a neurodegenerative disorder, predominantly characterized by the presence of motor symptoms. However, the non motor manifestations (NMM) are a frequent complaint in the PD patients. There is a lack of information about the risk factors associated with the NMM in these patients. The aim of this study is to evaluate the prevalence of the more common NMM in a population of PD patients and to determine the features associated with its development. We studied 124 ambulatory PD patients. NMM were defined by the presence of neuropsychiatric manifestations, cognitive disorder, autonomic dysfunction or sleep related problems. In a multivariate analysis we found that the years of evolution of the PD and the presence of cognitive dysfunction are the risk factors for the neuropsychiatric and autonomic manifestations, whereas axial impairment is a risk factor for cognitive disorders and dyskinesias is for sleep related problems. In conclusion, this study shows that the features related to the PD progression appear as the main risk factors associated with NMM.Academia Brasileira de Neurologia - ABNEURO2008-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000100006Arquivos de Neuro-Psiquiatria v.66 n.1 2008reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2008000100006info:eu-repo/semantics/openAccessJuri,CarlosViviani,PaolaChaná,Pedroeng2008-03-28T00:00:00Zoai:scielo:S0004-282X2008000100006Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2008-03-28T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Features associated with the development of non-motor manifestations in Parkinson's disease
title Features associated with the development of non-motor manifestations in Parkinson's disease
spellingShingle Features associated with the development of non-motor manifestations in Parkinson's disease
Juri,Carlos
Parkinson's disease
non motor manifestations
title_short Features associated with the development of non-motor manifestations in Parkinson's disease
title_full Features associated with the development of non-motor manifestations in Parkinson's disease
title_fullStr Features associated with the development of non-motor manifestations in Parkinson's disease
title_full_unstemmed Features associated with the development of non-motor manifestations in Parkinson's disease
title_sort Features associated with the development of non-motor manifestations in Parkinson's disease
author Juri,Carlos
author_facet Juri,Carlos
Viviani,Paola
Chaná,Pedro
author_role author
author2 Viviani,Paola
Chaná,Pedro
author2_role author
author
dc.contributor.author.fl_str_mv Juri,Carlos
Viviani,Paola
Chaná,Pedro
dc.subject.por.fl_str_mv Parkinson's disease
non motor manifestations
topic Parkinson's disease
non motor manifestations
description Parkinson's disease (PD) is a neurodegenerative disorder, predominantly characterized by the presence of motor symptoms. However, the non motor manifestations (NMM) are a frequent complaint in the PD patients. There is a lack of information about the risk factors associated with the NMM in these patients. The aim of this study is to evaluate the prevalence of the more common NMM in a population of PD patients and to determine the features associated with its development. We studied 124 ambulatory PD patients. NMM were defined by the presence of neuropsychiatric manifestations, cognitive disorder, autonomic dysfunction or sleep related problems. In a multivariate analysis we found that the years of evolution of the PD and the presence of cognitive dysfunction are the risk factors for the neuropsychiatric and autonomic manifestations, whereas axial impairment is a risk factor for cognitive disorders and dyskinesias is for sleep related problems. In conclusion, this study shows that the features related to the PD progression appear as the main risk factors associated with NMM.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000100006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000100006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2008000100006
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dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.66 n.1 2008
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
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