Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000500007 |
Resumo: | The aim of the study was to detect neurological abnormalities in human immunodeficiency virus (HIV) infected children. This was achieved by a prospective evaluation, from November/1995 to April/2000, of 43 HIV infected children (group I) and 40 HIV seroreverters children (group II) through neurological exam and neurodevelopmental tests: Denver Developmental Screening Test (DDST) and Clinical Adaptive Test / Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS). A control group (III), of 67 children, were evaluated by CAT/CLAMS. Hyperactivity, irritability and hypotonia were the findings on neurological examination, without statistical differences between group I and II. On CAT/CLAMS, the group I developmental quotient (DQ) was significantly lower than the other groups. The same occurred in DDST, with group I presenting significantly more failures than group II. Nineteen HIV children of group I had brain computed tomographic scan, with abnormalities in three of them (basal ganglia calcification, white matter hypodensity and asymmetry of lateral ventricles). We conclude that in HIV infected children a neurodevelopment delay occur early in the disease, and it can be detected by screening tests. |
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Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 childrenhuman immunodeficiency virus (HIV)neurodevelopment delayneurological screening testThe aim of the study was to detect neurological abnormalities in human immunodeficiency virus (HIV) infected children. This was achieved by a prospective evaluation, from November/1995 to April/2000, of 43 HIV infected children (group I) and 40 HIV seroreverters children (group II) through neurological exam and neurodevelopmental tests: Denver Developmental Screening Test (DDST) and Clinical Adaptive Test / Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS). A control group (III), of 67 children, were evaluated by CAT/CLAMS. Hyperactivity, irritability and hypotonia were the findings on neurological examination, without statistical differences between group I and II. On CAT/CLAMS, the group I developmental quotient (DQ) was significantly lower than the other groups. The same occurred in DDST, with group I presenting significantly more failures than group II. Nineteen HIV children of group I had brain computed tomographic scan, with abnormalities in three of them (basal ganglia calcification, white matter hypodensity and asymmetry of lateral ventricles). We conclude that in HIV infected children a neurodevelopment delay occur early in the disease, and it can be detected by screening tests.Academia Brasileira de Neurologia - ABNEURO2001-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000500007Arquivos de Neuro-Psiquiatria v.59 n.3B 2001reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2001000500007info:eu-repo/semantics/openAccessBruck,IsacTahan,Tony TannousCruz,Cristina Rodrigues daMartins,Luzilma Terezinha FlenikAntoniuk,Sérgio AntonioRodrigues,MarceloSouza,Sílvia Mara deBruyn,Laís Regina deeng2001-10-05T00:00:00Zoai:scielo:S0004-282X2001000500007Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2001-10-05T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
title |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
spellingShingle |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children Bruck,Isac human immunodeficiency virus (HIV) neurodevelopment delay neurological screening test |
title_short |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
title_full |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
title_fullStr |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
title_full_unstemmed |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
title_sort |
Developmental milestones of vertically HIV infected and seroreverters children: follow up of 83 children |
author |
Bruck,Isac |
author_facet |
Bruck,Isac Tahan,Tony Tannous Cruz,Cristina Rodrigues da Martins,Luzilma Terezinha Flenik Antoniuk,Sérgio Antonio Rodrigues,Marcelo Souza,Sílvia Mara de Bruyn,Laís Regina de |
author_role |
author |
author2 |
Tahan,Tony Tannous Cruz,Cristina Rodrigues da Martins,Luzilma Terezinha Flenik Antoniuk,Sérgio Antonio Rodrigues,Marcelo Souza,Sílvia Mara de Bruyn,Laís Regina de |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Bruck,Isac Tahan,Tony Tannous Cruz,Cristina Rodrigues da Martins,Luzilma Terezinha Flenik Antoniuk,Sérgio Antonio Rodrigues,Marcelo Souza,Sílvia Mara de Bruyn,Laís Regina de |
dc.subject.por.fl_str_mv |
human immunodeficiency virus (HIV) neurodevelopment delay neurological screening test |
topic |
human immunodeficiency virus (HIV) neurodevelopment delay neurological screening test |
description |
The aim of the study was to detect neurological abnormalities in human immunodeficiency virus (HIV) infected children. This was achieved by a prospective evaluation, from November/1995 to April/2000, of 43 HIV infected children (group I) and 40 HIV seroreverters children (group II) through neurological exam and neurodevelopmental tests: Denver Developmental Screening Test (DDST) and Clinical Adaptive Test / Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS). A control group (III), of 67 children, were evaluated by CAT/CLAMS. Hyperactivity, irritability and hypotonia were the findings on neurological examination, without statistical differences between group I and II. On CAT/CLAMS, the group I developmental quotient (DQ) was significantly lower than the other groups. The same occurred in DDST, with group I presenting significantly more failures than group II. Nineteen HIV children of group I had brain computed tomographic scan, with abnormalities in three of them (basal ganglia calcification, white matter hypodensity and asymmetry of lateral ventricles). We conclude that in HIV infected children a neurodevelopment delay occur early in the disease, and it can be detected by screening tests. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000500007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000500007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2001000500007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.59 n.3B 2001 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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