Bridge-therapy with enoxaparin in the preoperative period of endarterectomy

• Autor(a) principal: Raso,Jair Leopoldo
• Data de Publicação: 2010
• Outros Autores: Darwich,Rogério Zenóbio, Lucca Jr,Francisco de, Santana,Romeu Valle, Tanure,Marco Túlio, Cariri,Gustavo Agra, Furtado,Leopoldo Mandic Ferreira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivos de neuro-psiquiatria (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000500019
• topic: antiplatelet drugs; cervical clot; endarterectomy; enoxaparin; stroke

Cervical clot is one of the complications of endarterectomy. This risk may be higher in patients using aspirin or clopidogrel. On the other hand, stroke may occur if the medication is interrupted before surgery. We carried out a prospective study of 124 endarterectomies in 119 patients in which aspirin or clopidogrel was stopped and a bridge-therapy with enoxaparin was administered preoperatively. There was no case of stroke during the period of the bridge-therapy. One patient developed cervical clot (0.8%) in the fifth postoperative day. Mortality rate in this series was 0.8%. There was no complication directly related to the use of enoxaparin. Bridge-therapy with low molecular weight heparin is a safe strategy for patients elected for endarterectomy