A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD)
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000200119 |
Resumo: | Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia. |
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Arquivos de neuro-psiquiatria (Online) |
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A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD)Chron's diseaseinflammatory bowel diseaseperipheral neuropathysmall fiber neuropathyulcerative colitisNeurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia. Academia Brasileira de Neurologia - ABNEURO2015-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000200119Arquivos de Neuro-Psiquiatria v.73 n.2 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20140223info:eu-repo/semantics/openAccessGondim,Francisco de Assis AquinoOliveira,Gisele Ramos deTeles,Benedito Cadorno V.Souza,Marcellus H.L.P.Braga,Lucia L.B.C.Messias,Erick L.eng2015-02-23T00:00:00Zoai:scielo:S0004-282X2015000200119Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-02-23T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
title |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
spellingShingle |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) Gondim,Francisco de Assis Aquino Chron's disease inflammatory bowel disease peripheral neuropathy small fiber neuropathy ulcerative colitis |
title_short |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
title_full |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
title_fullStr |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
title_full_unstemmed |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
title_sort |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
author |
Gondim,Francisco de Assis Aquino |
author_facet |
Gondim,Francisco de Assis Aquino Oliveira,Gisele Ramos de Teles,Benedito Cadorno V. Souza,Marcellus H.L.P. Braga,Lucia L.B.C. Messias,Erick L. |
author_role |
author |
author2 |
Oliveira,Gisele Ramos de Teles,Benedito Cadorno V. Souza,Marcellus H.L.P. Braga,Lucia L.B.C. Messias,Erick L. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Gondim,Francisco de Assis Aquino Oliveira,Gisele Ramos de Teles,Benedito Cadorno V. Souza,Marcellus H.L.P. Braga,Lucia L.B.C. Messias,Erick L. |
dc.subject.por.fl_str_mv |
Chron's disease inflammatory bowel disease peripheral neuropathy small fiber neuropathy ulcerative colitis |
topic |
Chron's disease inflammatory bowel disease peripheral neuropathy small fiber neuropathy ulcerative colitis |
description |
Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000200119 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000200119 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20140223 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.73 n.2 2015 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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