Disability and progression in Afro-descendant patients with multiple sclerosis

Detalhes bibliográficos
Autor(a) principal: Aurenção,Juliana Calvet Kallenbach
Data de Publicação: 2016
Outros Autores: Vasconcelos,Claudia Cristina Ferreira, Thuler,Luiz Claudio Santos, Alvarenga,Regina Maria Papais
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000836
Resumo: ABSTRACT Multiple sclerosis (MS) prevalence is higher in Caucasian (CA) populations, narrowing the analysis of the impact of Afro-descendant (AD) populations in disease outcomes. Even so, recent studies observed that AD patients have a more severe course. The main objective of this study is to confirm and discuss, through a systematic review, that being AD is a risk factor for disability accumulation and/or severe progression in patients with MS. A systematic review of published data in the last eleven years was performed, which evaluated clinical aspects and long term disability in patients with MS. Fourteen studies were included. Of these fourteen articles, thirteen observed a relationship between ancestry and poorer outcome of MS. African ancestry is a condition inherent in the patient and should be considered as an initial clinical characteristic affecting prognosis, and influencing which therapeutic decision to make in initial phases.
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spelling Disability and progression in Afro-descendant patients with multiple sclerosismultiple sclerosisdisease progressiondisability, Afro-descentABSTRACT Multiple sclerosis (MS) prevalence is higher in Caucasian (CA) populations, narrowing the analysis of the impact of Afro-descendant (AD) populations in disease outcomes. Even so, recent studies observed that AD patients have a more severe course. The main objective of this study is to confirm and discuss, through a systematic review, that being AD is a risk factor for disability accumulation and/or severe progression in patients with MS. A systematic review of published data in the last eleven years was performed, which evaluated clinical aspects and long term disability in patients with MS. Fourteen studies were included. Of these fourteen articles, thirteen observed a relationship between ancestry and poorer outcome of MS. African ancestry is a condition inherent in the patient and should be considered as an initial clinical characteristic affecting prognosis, and influencing which therapeutic decision to make in initial phases.Academia Brasileira de Neurologia - ABNEURO2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000836Arquivos de Neuro-Psiquiatria v.74 n.10 2016reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20160118info:eu-repo/semantics/openAccessAurenção,Juliana Calvet KallenbachVasconcelos,Claudia Cristina FerreiraThuler,Luiz Claudio SantosAlvarenga,Regina Maria Papaiseng2016-10-14T00:00:00Zoai:scielo:S0004-282X2016001000836Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2016-10-14T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Disability and progression in Afro-descendant patients with multiple sclerosis
title Disability and progression in Afro-descendant patients with multiple sclerosis
spellingShingle Disability and progression in Afro-descendant patients with multiple sclerosis
Aurenção,Juliana Calvet Kallenbach
multiple sclerosis
disease progression
disability, Afro-descent
title_short Disability and progression in Afro-descendant patients with multiple sclerosis
title_full Disability and progression in Afro-descendant patients with multiple sclerosis
title_fullStr Disability and progression in Afro-descendant patients with multiple sclerosis
title_full_unstemmed Disability and progression in Afro-descendant patients with multiple sclerosis
title_sort Disability and progression in Afro-descendant patients with multiple sclerosis
author Aurenção,Juliana Calvet Kallenbach
author_facet Aurenção,Juliana Calvet Kallenbach
Vasconcelos,Claudia Cristina Ferreira
Thuler,Luiz Claudio Santos
Alvarenga,Regina Maria Papais
author_role author
author2 Vasconcelos,Claudia Cristina Ferreira
Thuler,Luiz Claudio Santos
Alvarenga,Regina Maria Papais
author2_role author
author
author
dc.contributor.author.fl_str_mv Aurenção,Juliana Calvet Kallenbach
Vasconcelos,Claudia Cristina Ferreira
Thuler,Luiz Claudio Santos
Alvarenga,Regina Maria Papais
dc.subject.por.fl_str_mv multiple sclerosis
disease progression
disability, Afro-descent
topic multiple sclerosis
disease progression
disability, Afro-descent
description ABSTRACT Multiple sclerosis (MS) prevalence is higher in Caucasian (CA) populations, narrowing the analysis of the impact of Afro-descendant (AD) populations in disease outcomes. Even so, recent studies observed that AD patients have a more severe course. The main objective of this study is to confirm and discuss, through a systematic review, that being AD is a risk factor for disability accumulation and/or severe progression in patients with MS. A systematic review of published data in the last eleven years was performed, which evaluated clinical aspects and long term disability in patients with MS. Fourteen studies were included. Of these fourteen articles, thirteen observed a relationship between ancestry and poorer outcome of MS. African ancestry is a condition inherent in the patient and should be considered as an initial clinical characteristic affecting prognosis, and influencing which therapeutic decision to make in initial phases.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000836
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000836
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282X20160118
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.74 n.10 2016
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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