Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults

Detalhes bibliográficos
Autor(a) principal: APRIGIO,Danielle
Data de Publicação: 2020
Outros Autores: TANAKA,Guaraci Ken, BITTENCOURT,Juliana, GONGORA,Mariana, TEIXEIRA,Silmar, CAGY,Mauricio, BUDDE,Henning, ORSINI,Marco, RIBEIRO,Pedro, VELASQUES,Bruna
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199
Resumo: Abstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase.
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spelling Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adultselectroencephalographybeta rhythmmethylphenidaterisperidonemotor imageryAbstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase.Academia Brasileira de Neurologia - ABNEURO2020-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199Arquivos de Neuro-Psiquiatria v.78 n.4 2020reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20190186info:eu-repo/semantics/openAccessAPRIGIO,DanielleTANAKA,Guaraci KenBITTENCOURT,JulianaGONGORA,MarianaTEIXEIRA,SilmarCAGY,MauricioBUDDE,HenningORSINI,MarcoRIBEIRO,PedroVELASQUES,Brunaeng2020-04-27T00:00:00Zoai:scielo:S0004-282X2020000400199Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2020-04-27T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
title Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
spellingShingle Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
APRIGIO,Danielle
electroencephalography
beta rhythm
methylphenidate
risperidone
motor imagery
title_short Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
title_full Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
title_fullStr Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
title_full_unstemmed Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
title_sort Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
author APRIGIO,Danielle
author_facet APRIGIO,Danielle
TANAKA,Guaraci Ken
BITTENCOURT,Juliana
GONGORA,Mariana
TEIXEIRA,Silmar
CAGY,Mauricio
BUDDE,Henning
ORSINI,Marco
RIBEIRO,Pedro
VELASQUES,Bruna
author_role author
author2 TANAKA,Guaraci Ken
BITTENCOURT,Juliana
GONGORA,Mariana
TEIXEIRA,Silmar
CAGY,Mauricio
BUDDE,Henning
ORSINI,Marco
RIBEIRO,Pedro
VELASQUES,Bruna
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv APRIGIO,Danielle
TANAKA,Guaraci Ken
BITTENCOURT,Juliana
GONGORA,Mariana
TEIXEIRA,Silmar
CAGY,Mauricio
BUDDE,Henning
ORSINI,Marco
RIBEIRO,Pedro
VELASQUES,Bruna
dc.subject.por.fl_str_mv electroencephalography
beta rhythm
methylphenidate
risperidone
motor imagery
topic electroencephalography
beta rhythm
methylphenidate
risperidone
motor imagery
description Abstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20190186
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.78 n.4 2020
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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