Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects

Detalhes bibliográficos
Autor(a) principal: Aguiar,Aline de Almeida Xavier
Data de Publicação: 2010
Outros Autores: Carvalho,André Ferrer, Costa,Carlos Mauricio de Castro, Fernandes,José Marcelino Aragão, D'Almeida,José Artur Costa, Furtado,Luís Edmundo Teixeira de Arruda, Cunha,Francisco Marcos Bezerra da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003
Resumo: A retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries.
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spelling Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspectsmyasthenia gravisclinical evaluationepidemiologyA retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries.Academia Brasileira de Neurologia - ABNEURO2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003Arquivos de Neuro-Psiquiatria v.68 n.6 2010reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2010000600003info:eu-repo/semantics/openAccessAguiar,Aline de Almeida XavierCarvalho,André FerrerCosta,Carlos Mauricio de CastroFernandes,José Marcelino AragãoD'Almeida,José Artur CostaFurtado,Luís Edmundo Teixeira de ArrudaCunha,Francisco Marcos Bezerra daeng2011-01-06T00:00:00Zoai:scielo:S0004-282X2010000600003Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2011-01-06T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
title Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
spellingShingle Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
Aguiar,Aline de Almeida Xavier
myasthenia gravis
clinical evaluation
epidemiology
title_short Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
title_full Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
title_fullStr Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
title_full_unstemmed Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
title_sort Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
author Aguiar,Aline de Almeida Xavier
author_facet Aguiar,Aline de Almeida Xavier
Carvalho,André Ferrer
Costa,Carlos Mauricio de Castro
Fernandes,José Marcelino Aragão
D'Almeida,José Artur Costa
Furtado,Luís Edmundo Teixeira de Arruda
Cunha,Francisco Marcos Bezerra da
author_role author
author2 Carvalho,André Ferrer
Costa,Carlos Mauricio de Castro
Fernandes,José Marcelino Aragão
D'Almeida,José Artur Costa
Furtado,Luís Edmundo Teixeira de Arruda
Cunha,Francisco Marcos Bezerra da
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Aguiar,Aline de Almeida Xavier
Carvalho,André Ferrer
Costa,Carlos Mauricio de Castro
Fernandes,José Marcelino Aragão
D'Almeida,José Artur Costa
Furtado,Luís Edmundo Teixeira de Arruda
Cunha,Francisco Marcos Bezerra da
dc.subject.por.fl_str_mv myasthenia gravis
clinical evaluation
epidemiology
topic myasthenia gravis
clinical evaluation
epidemiology
description A retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2010000600003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.68 n.6 2010
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
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instname_str Academia Brasileira de Neurologia
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reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
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