Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003 |
Resumo: | A retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries. |
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Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspectsmyasthenia gravisclinical evaluationepidemiologyA retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries.Academia Brasileira de Neurologia - ABNEURO2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003Arquivos de Neuro-Psiquiatria v.68 n.6 2010reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2010000600003info:eu-repo/semantics/openAccessAguiar,Aline de Almeida XavierCarvalho,André FerrerCosta,Carlos Mauricio de CastroFernandes,José Marcelino AragãoD'Almeida,José Artur CostaFurtado,Luís Edmundo Teixeira de ArrudaCunha,Francisco Marcos Bezerra daeng2011-01-06T00:00:00Zoai:scielo:S0004-282X2010000600003Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2011-01-06T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
title |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
spellingShingle |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects Aguiar,Aline de Almeida Xavier myasthenia gravis clinical evaluation epidemiology |
title_short |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
title_full |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
title_fullStr |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
title_full_unstemmed |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
title_sort |
Myasthenia gravis in Ceará, Brazil: clinical and epidemiological aspects |
author |
Aguiar,Aline de Almeida Xavier |
author_facet |
Aguiar,Aline de Almeida Xavier Carvalho,André Ferrer Costa,Carlos Mauricio de Castro Fernandes,José Marcelino Aragão D'Almeida,José Artur Costa Furtado,Luís Edmundo Teixeira de Arruda Cunha,Francisco Marcos Bezerra da |
author_role |
author |
author2 |
Carvalho,André Ferrer Costa,Carlos Mauricio de Castro Fernandes,José Marcelino Aragão D'Almeida,José Artur Costa Furtado,Luís Edmundo Teixeira de Arruda Cunha,Francisco Marcos Bezerra da |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Aguiar,Aline de Almeida Xavier Carvalho,André Ferrer Costa,Carlos Mauricio de Castro Fernandes,José Marcelino Aragão D'Almeida,José Artur Costa Furtado,Luís Edmundo Teixeira de Arruda Cunha,Francisco Marcos Bezerra da |
dc.subject.por.fl_str_mv |
myasthenia gravis clinical evaluation epidemiology |
topic |
myasthenia gravis clinical evaluation epidemiology |
description |
A retrospective chart review was performed on patients diagnosed as having myasthenia gravis in Ceará State, Brazil and who were followed from October 1981 to June 2009. Clinical and epidemiologic aspects were evaluated. In this work, 122 patients were studied, of whom 85 (69.7%) were females and 37 (30.3%) were males. The disease duration ranged from five months to 50 years (8.9±8.1 years). Age at the first symptoms varied from 0 to 74 years (31.9±14.4 years). The first main symptoms and signs were ptosis, diplopia and limb weakness. Generalized myasthenia was the most common clinical presentation, but 5.1% (n=6) persisted as ocular myasthenia. Thymectomy was performed in 42.6% (n=52) of myasthenic patients. A thymoma was present in 10 patients. Serum acetylcholine receptor (AChR) antibodies were present in 80% (n=20) of specimens tested. The data presented are similar to those of studies performed in other countries. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2010000600003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.68 n.6 2010 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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