Dementia Pugilistica with clinical features of Alzheimer's disease

Detalhes bibliográficos
Autor(a) principal: Areza-Fegyveres,Renata
Data de Publicação: 2007
Outros Autores: Rosemberg,Sergio, Castro,Rosa Maria R.P.S., Porto,Claudia Sellitto, Bahia,Valéria Santoro, Caramelli,Paulo, Nitrini,Ricardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000500019
Resumo: A 61-year-old ex-boxer presented with a three-year history of progressive memory decline. During a seven-year follow-up period, there was a continuous cognitive decline, very similar to that usually observed in Alzheimer's disease. Parkinsonian, pyramidal or cerebellar signs were conspicuously absent. Neuropathological examination revealed the typical features of dementia pugilistica: cavum septi pellucidi with multiple fenestrations, numerous neurofibrillary tangles in the cerebral isocortex and hippocampus (and rare senile plaques). Immunohistochemistry disclosed a high number of tau protein deposits and scarce beta-amyloid staining. This case shows that dementia pugilistica may present with clinical features practically undistinguishable from Alzheimer's disease.
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spelling Dementia Pugilistica with clinical features of Alzheimer's diseasedementiadementia pugilisticapunch drunkAlzheimer's diseasechronic traumatic encephalopathyparkinsonian/motor signsneuropathologyA 61-year-old ex-boxer presented with a three-year history of progressive memory decline. During a seven-year follow-up period, there was a continuous cognitive decline, very similar to that usually observed in Alzheimer's disease. Parkinsonian, pyramidal or cerebellar signs were conspicuously absent. Neuropathological examination revealed the typical features of dementia pugilistica: cavum septi pellucidi with multiple fenestrations, numerous neurofibrillary tangles in the cerebral isocortex and hippocampus (and rare senile plaques). Immunohistochemistry disclosed a high number of tau protein deposits and scarce beta-amyloid staining. This case shows that dementia pugilistica may present with clinical features practically undistinguishable from Alzheimer's disease.Academia Brasileira de Neurologia - ABNEURO2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000500019Arquivos de Neuro-Psiquiatria v.65 n.3b 2007reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2007000500019info:eu-repo/semantics/openAccessAreza-Fegyveres,RenataRosemberg,SergioCastro,Rosa Maria R.P.S.Porto,Claudia SellittoBahia,Valéria SantoroCaramelli,PauloNitrini,Ricardoeng2008-04-11T00:00:00Zoai:scielo:S0004-282X2007000500019Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2008-04-11T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Dementia Pugilistica with clinical features of Alzheimer's disease
title Dementia Pugilistica with clinical features of Alzheimer's disease
spellingShingle Dementia Pugilistica with clinical features of Alzheimer's disease
Areza-Fegyveres,Renata
dementia
dementia pugilistica
punch drunk
Alzheimer's disease
chronic traumatic encephalopathy
parkinsonian/motor signs
neuropathology
title_short Dementia Pugilistica with clinical features of Alzheimer's disease
title_full Dementia Pugilistica with clinical features of Alzheimer's disease
title_fullStr Dementia Pugilistica with clinical features of Alzheimer's disease
title_full_unstemmed Dementia Pugilistica with clinical features of Alzheimer's disease
title_sort Dementia Pugilistica with clinical features of Alzheimer's disease
author Areza-Fegyveres,Renata
author_facet Areza-Fegyveres,Renata
Rosemberg,Sergio
Castro,Rosa Maria R.P.S.
Porto,Claudia Sellitto
Bahia,Valéria Santoro
Caramelli,Paulo
Nitrini,Ricardo
author_role author
author2 Rosemberg,Sergio
Castro,Rosa Maria R.P.S.
Porto,Claudia Sellitto
Bahia,Valéria Santoro
Caramelli,Paulo
Nitrini,Ricardo
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Areza-Fegyveres,Renata
Rosemberg,Sergio
Castro,Rosa Maria R.P.S.
Porto,Claudia Sellitto
Bahia,Valéria Santoro
Caramelli,Paulo
Nitrini,Ricardo
dc.subject.por.fl_str_mv dementia
dementia pugilistica
punch drunk
Alzheimer's disease
chronic traumatic encephalopathy
parkinsonian/motor signs
neuropathology
topic dementia
dementia pugilistica
punch drunk
Alzheimer's disease
chronic traumatic encephalopathy
parkinsonian/motor signs
neuropathology
description A 61-year-old ex-boxer presented with a three-year history of progressive memory decline. During a seven-year follow-up period, there was a continuous cognitive decline, very similar to that usually observed in Alzheimer's disease. Parkinsonian, pyramidal or cerebellar signs were conspicuously absent. Neuropathological examination revealed the typical features of dementia pugilistica: cavum septi pellucidi with multiple fenestrations, numerous neurofibrillary tangles in the cerebral isocortex and hippocampus (and rare senile plaques). Immunohistochemistry disclosed a high number of tau protein deposits and scarce beta-amyloid staining. This case shows that dementia pugilistica may present with clinical features practically undistinguishable from Alzheimer's disease.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000500019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000500019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2007000500019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.65 n.3b 2007
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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