Hypertrophic pachymeningitis: case report

• Autor(a) principal: Deus-Silva,Leonardo de
• Data de Publicação: 2003
• Outros Autores: Queiroz,Luciano de Souza, Zanardi,Verônica de Araújo, Ghizoni,Enrico, Pereira,Hoyama da Costa, Malveira,George Linard Silva, Pirani Jr,Clodoaldo, Damasceno,Benito Pereira, Cendes,Fernando
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivos de neuro-psiquiatria (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100021
• topic: hypertrophic pachymeningits; neurosarcoidosis; psychosis; optic neuropathy

Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.