Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy

Detalhes bibliográficos
Autor(a) principal: Parreira,Samara Lamounier Santana
Data de Publicação: 2010
Outros Autores: Resende,Maria Bernadete Dutra, Zanoteli,Edmar, Carvalho,Mary Souza, Marie,Suely Kazue, Reed,Umbertina Conti
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000500002
Resumo: OBJECTIVE: To compare muscle strength (MS) and motor function in patients with Duchenne muscular dystrophy (DMD) receiving steroids for different times against the natural evolution of DMD described by Scott et al. METHOD: 90 patients with DMD (aged 5- 12 years), receiving steroids for one to seven years, were evaluated by Medical Research Council Scale (MRC) and Hammersmith motor ability score. The relation between MS and motor abilities measurement from our data and Scott's ones were ascertained statistically. RESULTS: The relation between patient's age and Hammersmith scores revealed decrease of 0.76 point per year for age against decrease of 2.23 points on Scott's study. The relation between MRC scale and patient's age showed decrease of 0.80 point per year of age against decrease of 3.65 points on Scott's study. CONCLUSION: In patients with DMD aged five to 12 years the progression of the disease is delayed by steroids and the motor function is less reduced than muscular strength.
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spelling Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapyDuchenne muscular dystrophysteroidsmuscle strengthmotor abilityMRC scaleHammersmith motor ability scoreOBJECTIVE: To compare muscle strength (MS) and motor function in patients with Duchenne muscular dystrophy (DMD) receiving steroids for different times against the natural evolution of DMD described by Scott et al. METHOD: 90 patients with DMD (aged 5- 12 years), receiving steroids for one to seven years, were evaluated by Medical Research Council Scale (MRC) and Hammersmith motor ability score. The relation between MS and motor abilities measurement from our data and Scott's ones were ascertained statistically. RESULTS: The relation between patient's age and Hammersmith scores revealed decrease of 0.76 point per year for age against decrease of 2.23 points on Scott's study. The relation between MRC scale and patient's age showed decrease of 0.80 point per year of age against decrease of 3.65 points on Scott's study. CONCLUSION: In patients with DMD aged five to 12 years the progression of the disease is delayed by steroids and the motor function is less reduced than muscular strength.Academia Brasileira de Neurologia - ABNEURO2010-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000500002Arquivos de Neuro-Psiquiatria v.68 n.5 2010reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2010000500002info:eu-repo/semantics/openAccessParreira,Samara Lamounier SantanaResende,Maria Bernadete DutraZanoteli,EdmarCarvalho,Mary SouzaMarie,Suely KazueReed,Umbertina Contieng2010-10-20T00:00:00Zoai:scielo:S0004-282X2010000500002Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2010-10-20T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
title Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
spellingShingle Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
Parreira,Samara Lamounier Santana
Duchenne muscular dystrophy
steroids
muscle strength
motor ability
MRC scale
Hammersmith motor ability score
title_short Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
title_full Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
title_fullStr Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
title_full_unstemmed Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
title_sort Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy
author Parreira,Samara Lamounier Santana
author_facet Parreira,Samara Lamounier Santana
Resende,Maria Bernadete Dutra
Zanoteli,Edmar
Carvalho,Mary Souza
Marie,Suely Kazue
Reed,Umbertina Conti
author_role author
author2 Resende,Maria Bernadete Dutra
Zanoteli,Edmar
Carvalho,Mary Souza
Marie,Suely Kazue
Reed,Umbertina Conti
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Parreira,Samara Lamounier Santana
Resende,Maria Bernadete Dutra
Zanoteli,Edmar
Carvalho,Mary Souza
Marie,Suely Kazue
Reed,Umbertina Conti
dc.subject.por.fl_str_mv Duchenne muscular dystrophy
steroids
muscle strength
motor ability
MRC scale
Hammersmith motor ability score
topic Duchenne muscular dystrophy
steroids
muscle strength
motor ability
MRC scale
Hammersmith motor ability score
description OBJECTIVE: To compare muscle strength (MS) and motor function in patients with Duchenne muscular dystrophy (DMD) receiving steroids for different times against the natural evolution of DMD described by Scott et al. METHOD: 90 patients with DMD (aged 5- 12 years), receiving steroids for one to seven years, were evaluated by Medical Research Council Scale (MRC) and Hammersmith motor ability score. The relation between MS and motor abilities measurement from our data and Scott's ones were ascertained statistically. RESULTS: The relation between patient's age and Hammersmith scores revealed decrease of 0.76 point per year for age against decrease of 2.23 points on Scott's study. The relation between MRC scale and patient's age showed decrease of 0.80 point per year of age against decrease of 3.65 points on Scott's study. CONCLUSION: In patients with DMD aged five to 12 years the progression of the disease is delayed by steroids and the motor function is less reduced than muscular strength.
publishDate 2010
dc.date.none.fl_str_mv 2010-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000500002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000500002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2010000500002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.68 n.5 2010
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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