Clinical, neurovascular and neuropathological features in sneddon's syndrome
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300005 |
Resumo: | Sneddon's syndrome (SS) is characterized by ischemic cerebrovascular episodes and livedo reticularis. It is more common in young women and can also be associated with valvulopathy, a history of spontaneous abortion, renal involvement and vascular dementia. We describe three cases of young women with this disease. The patients had repeated ischemic cerebral episodes, livedo reticularis and thrombocytopenia. CT and MRI showed strokes and cerebral atrophy. Autopsy in one of the patients revealed cerebral infarctions. Anticardiolipin antibodies were detected in two patients. Antiphospholipid antibodies may be found in some patients with ischemic cerebrovascular events and livedo reticularis. SS may thus be associated with antiphospholipid syndrome. We described three new cases of SS and discuss the pathophysiology of this disease. |
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Clinical, neurovascular and neuropathological features in sneddon's syndromeantiphospholipid syndromecerebrovascular diseasesneuroimagingneuropathologySneddon's syndromeSneddon's syndrome (SS) is characterized by ischemic cerebrovascular episodes and livedo reticularis. It is more common in young women and can also be associated with valvulopathy, a history of spontaneous abortion, renal involvement and vascular dementia. We describe three cases of young women with this disease. The patients had repeated ischemic cerebral episodes, livedo reticularis and thrombocytopenia. CT and MRI showed strokes and cerebral atrophy. Autopsy in one of the patients revealed cerebral infarctions. Anticardiolipin antibodies were detected in two patients. Antiphospholipid antibodies may be found in some patients with ischemic cerebrovascular events and livedo reticularis. SS may thus be associated with antiphospholipid syndrome. We described three new cases of SS and discuss the pathophysiology of this disease.Academia Brasileira de Neurologia - ABNEURO2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300005Arquivos de Neuro-Psiquiatria v.65 n.2b 2007reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2007000300005info:eu-repo/semantics/openAccessMarinho,Jaqueline LuvisottoPiovesan,Élcio JuliatoLeite Neto,Moacir PereiraKotze,Luiz RobertoNoronha,Lúcia deTwardowschy,Carlos AlexandreLange,Marcos ChristianoScola,Rosana HermíniaZétola,Viviane H. FlumignanNóvak,Edison MatosWerneck,Lineu Césareng2007-07-24T00:00:00Zoai:scielo:S0004-282X2007000300005Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2007-07-24T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
title |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
spellingShingle |
Clinical, neurovascular and neuropathological features in sneddon's syndrome Marinho,Jaqueline Luvisotto antiphospholipid syndrome cerebrovascular diseases neuroimaging neuropathology Sneddon's syndrome |
title_short |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
title_full |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
title_fullStr |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
title_full_unstemmed |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
title_sort |
Clinical, neurovascular and neuropathological features in sneddon's syndrome |
author |
Marinho,Jaqueline Luvisotto |
author_facet |
Marinho,Jaqueline Luvisotto Piovesan,Élcio Juliato Leite Neto,Moacir Pereira Kotze,Luiz Roberto Noronha,Lúcia de Twardowschy,Carlos Alexandre Lange,Marcos Christiano Scola,Rosana Hermínia Zétola,Viviane H. Flumignan Nóvak,Edison Matos Werneck,Lineu César |
author_role |
author |
author2 |
Piovesan,Élcio Juliato Leite Neto,Moacir Pereira Kotze,Luiz Roberto Noronha,Lúcia de Twardowschy,Carlos Alexandre Lange,Marcos Christiano Scola,Rosana Hermínia Zétola,Viviane H. Flumignan Nóvak,Edison Matos Werneck,Lineu César |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Marinho,Jaqueline Luvisotto Piovesan,Élcio Juliato Leite Neto,Moacir Pereira Kotze,Luiz Roberto Noronha,Lúcia de Twardowschy,Carlos Alexandre Lange,Marcos Christiano Scola,Rosana Hermínia Zétola,Viviane H. Flumignan Nóvak,Edison Matos Werneck,Lineu César |
dc.subject.por.fl_str_mv |
antiphospholipid syndrome cerebrovascular diseases neuroimaging neuropathology Sneddon's syndrome |
topic |
antiphospholipid syndrome cerebrovascular diseases neuroimaging neuropathology Sneddon's syndrome |
description |
Sneddon's syndrome (SS) is characterized by ischemic cerebrovascular episodes and livedo reticularis. It is more common in young women and can also be associated with valvulopathy, a history of spontaneous abortion, renal involvement and vascular dementia. We describe three cases of young women with this disease. The patients had repeated ischemic cerebral episodes, livedo reticularis and thrombocytopenia. CT and MRI showed strokes and cerebral atrophy. Autopsy in one of the patients revealed cerebral infarctions. Anticardiolipin antibodies were detected in two patients. Antiphospholipid antibodies may be found in some patients with ischemic cerebrovascular events and livedo reticularis. SS may thus be associated with antiphospholipid syndrome. We described three new cases of SS and discuss the pathophysiology of this disease. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2007000300005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.65 n.2b 2007 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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