Experimental nodel of C6 brain tumors in athymic rats

Detalhes bibliográficos
Autor(a) principal: Miura,Flávio K.
Data de Publicação: 2008
Outros Autores: Alves,Maria José Ferreira, Rocha,Mussya Cisotto, Silva,Roseli S., Oba-Shinjo,Sueli M., Uno,M., Colin,C., Sogayar,M.C., Marie,Sueli K.N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000200019
Resumo: Malignant brain tumor experimental models tend to employ cells that are immunologically compatible with the receptor animal. In this study, we have proposed an experimental model of encephalic tumor development by injecting C6 cells into athymic Rowett rats, aiming at reaching a model which more closely resembles to the human glioma tumor. In our model, we observed micro-infiltration of tumor cell clusters in the vicinity of the main tumor mass, and of more distal isolated tumor cells immersed in normal encephalic parenchyma. This degree of infiltration is superior to that usually observed in other C6 models.
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spelling Experimental nodel of C6 brain tumors in athymic ratsbrain tumorC6 cellsexperimental modelgliomaMalignant brain tumor experimental models tend to employ cells that are immunologically compatible with the receptor animal. In this study, we have proposed an experimental model of encephalic tumor development by injecting C6 cells into athymic Rowett rats, aiming at reaching a model which more closely resembles to the human glioma tumor. In our model, we observed micro-infiltration of tumor cell clusters in the vicinity of the main tumor mass, and of more distal isolated tumor cells immersed in normal encephalic parenchyma. This degree of infiltration is superior to that usually observed in other C6 models.Academia Brasileira de Neurologia - ABNEURO2008-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000200019Arquivos de Neuro-Psiquiatria v.66 n.2a 2008reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2008000200019info:eu-repo/semantics/openAccessMiura,Flávio K.Alves,Maria José FerreiraRocha,Mussya CisottoSilva,Roseli S.Oba-Shinjo,Sueli M.Uno,M.Colin,C.Sogayar,M.C.Marie,Sueli K.N.eng2008-06-02T00:00:00Zoai:scielo:S0004-282X2008000200019Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2008-06-02T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Experimental nodel of C6 brain tumors in athymic rats
title Experimental nodel of C6 brain tumors in athymic rats
spellingShingle Experimental nodel of C6 brain tumors in athymic rats
Miura,Flávio K.
brain tumor
C6 cells
experimental model
glioma
title_short Experimental nodel of C6 brain tumors in athymic rats
title_full Experimental nodel of C6 brain tumors in athymic rats
title_fullStr Experimental nodel of C6 brain tumors in athymic rats
title_full_unstemmed Experimental nodel of C6 brain tumors in athymic rats
title_sort Experimental nodel of C6 brain tumors in athymic rats
author Miura,Flávio K.
author_facet Miura,Flávio K.
Alves,Maria José Ferreira
Rocha,Mussya Cisotto
Silva,Roseli S.
Oba-Shinjo,Sueli M.
Uno,M.
Colin,C.
Sogayar,M.C.
Marie,Sueli K.N.
author_role author
author2 Alves,Maria José Ferreira
Rocha,Mussya Cisotto
Silva,Roseli S.
Oba-Shinjo,Sueli M.
Uno,M.
Colin,C.
Sogayar,M.C.
Marie,Sueli K.N.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Miura,Flávio K.
Alves,Maria José Ferreira
Rocha,Mussya Cisotto
Silva,Roseli S.
Oba-Shinjo,Sueli M.
Uno,M.
Colin,C.
Sogayar,M.C.
Marie,Sueli K.N.
dc.subject.por.fl_str_mv brain tumor
C6 cells
experimental model
glioma
topic brain tumor
C6 cells
experimental model
glioma
description Malignant brain tumor experimental models tend to employ cells that are immunologically compatible with the receptor animal. In this study, we have proposed an experimental model of encephalic tumor development by injecting C6 cells into athymic Rowett rats, aiming at reaching a model which more closely resembles to the human glioma tumor. In our model, we observed micro-infiltration of tumor cell clusters in the vicinity of the main tumor mass, and of more distal isolated tumor cells immersed in normal encephalic parenchyma. This degree of infiltration is superior to that usually observed in other C6 models.
publishDate 2008
dc.date.none.fl_str_mv 2008-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000200019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000200019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2008000200019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.66 n.2a 2008
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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