Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
Resumo: | INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome. |
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Arquivos de neuro-psiquiatria (Online) |
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Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsyepilepsytemporal lobeepilepsy surgeryelectroencephalographyINTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome.Academia Brasileira de Neurologia - ABNEURO2012-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009Arquivos de Neuro-Psiquiatria v.70 n.9 2012reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2012000900009info:eu-repo/semantics/openAccessSainju,Rup KamalWolf,Bethany JacobsBonilha,LeonardoMartz,Gabrieleng2012-09-12T00:00:00Zoai:scielo:S0004-282X2012000900009Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2012-09-12T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
title |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
spellingShingle |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy Sainju,Rup Kamal epilepsy temporal lobe epilepsy surgery electroencephalography |
title_short |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
title_full |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
title_fullStr |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
title_full_unstemmed |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
title_sort |
Relationship of number of seizures recorded on video-EEG to surgical outcome in refractory medial temporal lobe epilepsy |
author |
Sainju,Rup Kamal |
author_facet |
Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
author_role |
author |
author2 |
Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Sainju,Rup Kamal Wolf,Bethany Jacobs Bonilha,Leonardo Martz,Gabriel |
dc.subject.por.fl_str_mv |
epilepsy temporal lobe epilepsy surgery electroencephalography |
topic |
epilepsy temporal lobe epilepsy surgery electroencephalography |
description |
INTRODUCTION: Surgical planning for refractory medial temporal lobe epilepsy (rMTLE) relies on seizure localization by ictal electroencephalography (EEG). Multiple factors impact the number of seizures recorded. We evaluated whether seizure freedom correlated to the number of seizures recorded, and the related factors. METHODS: We collected data for 32 patients with rMTLE who underwent anterior temporal lobectomy. Primary analysis evaluated number of seizures captured as a predictor of surgical outcome. Subsequent analyses explored factors that may seizure number. RESULTS: Number of seizures recorded did not predict seizure freedom. More seizures were recorded with more days of seizure occurrence (p<0.001), seizure clusters (p<0.011) and poorly localized seizures (PLSz) (p=0.004). Regression modeling showed a trend for subjects with fewer recorded poorly localized seizures to have better surgical outcome (p=0.052). CONCLUSIONS: Total number of recorded seizures does not predict surgical outcome. Patients with more PLSz may have worse outcome. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900009 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2012000900009 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.70 n.9 2012 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212773801230336 |