Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage

Detalhes bibliográficos
Autor(a) principal: Romero,Flávio Ramalho
Data de Publicação: 2012
Outros Autores: Bertolini,Eduardo de Freitas, Figueiredo,Eberval G., Teixeira,Manoel Jacobsen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000300009
Resumo: OBJECTIVES: Our aim was to evaluate the relationship between serum C-reactive protein (CRP) levels and the neurological prognosis and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Eighty-two adult patients with aSAH diagnoses were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, cranial CT scans, digital subtraction angiography studies and daily neurological examinations were recorded. Serial serum CRP measurements were obtained daily between admission and the tenth day. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to assess the prognosis. RESULTS: Serum CRP levels were related to severity of aSAH. Patients with lower GCS scores and higher Hunt and Hess and Fisher grades presented statistically significant higher serum CRP levels. Patients with higher serum CRP levels had a less favorable prognosis. CONCLUSIONS: Increased serum CRP levels were strongly associated with worse clinical prognosis in this study.
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spelling Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhageC-reactive proteinsubarachnoid hemorrhagevasospasmintracranial aneurysmOBJECTIVES: Our aim was to evaluate the relationship between serum C-reactive protein (CRP) levels and the neurological prognosis and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Eighty-two adult patients with aSAH diagnoses were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, cranial CT scans, digital subtraction angiography studies and daily neurological examinations were recorded. Serial serum CRP measurements were obtained daily between admission and the tenth day. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to assess the prognosis. RESULTS: Serum CRP levels were related to severity of aSAH. Patients with lower GCS scores and higher Hunt and Hess and Fisher grades presented statistically significant higher serum CRP levels. Patients with higher serum CRP levels had a less favorable prognosis. CONCLUSIONS: Increased serum CRP levels were strongly associated with worse clinical prognosis in this study.Academia Brasileira de Neurologia - ABNEURO2012-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000300009Arquivos de Neuro-Psiquiatria v.70 n.3 2012reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2012000300009info:eu-repo/semantics/openAccessRomero,Flávio RamalhoBertolini,Eduardo de FreitasFigueiredo,Eberval G.Teixeira,Manoel Jacobseneng2015-06-09T00:00:00Zoai:scielo:S0004-282X2012000300009Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-06-09T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
title Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
spellingShingle Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
Romero,Flávio Ramalho
C-reactive protein
subarachnoid hemorrhage
vasospasm
intracranial aneurysm
title_short Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
title_full Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
title_fullStr Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
title_full_unstemmed Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
title_sort Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage
author Romero,Flávio Ramalho
author_facet Romero,Flávio Ramalho
Bertolini,Eduardo de Freitas
Figueiredo,Eberval G.
Teixeira,Manoel Jacobsen
author_role author
author2 Bertolini,Eduardo de Freitas
Figueiredo,Eberval G.
Teixeira,Manoel Jacobsen
author2_role author
author
author
dc.contributor.author.fl_str_mv Romero,Flávio Ramalho
Bertolini,Eduardo de Freitas
Figueiredo,Eberval G.
Teixeira,Manoel Jacobsen
dc.subject.por.fl_str_mv C-reactive protein
subarachnoid hemorrhage
vasospasm
intracranial aneurysm
topic C-reactive protein
subarachnoid hemorrhage
vasospasm
intracranial aneurysm
description OBJECTIVES: Our aim was to evaluate the relationship between serum C-reactive protein (CRP) levels and the neurological prognosis and development of vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Eighty-two adult patients with aSAH diagnoses were prospectively evaluated. Glasgow Coma Scale (GCS) score, Hunt and Hess grade, Fisher grade, cranial CT scans, digital subtraction angiography studies and daily neurological examinations were recorded. Serial serum CRP measurements were obtained daily between admission and the tenth day. Glasgow Outcome Scale (GOS) and the modified Rankin Scale (mRS) were used to assess the prognosis. RESULTS: Serum CRP levels were related to severity of aSAH. Patients with lower GCS scores and higher Hunt and Hess and Fisher grades presented statistically significant higher serum CRP levels. Patients with higher serum CRP levels had a less favorable prognosis. CONCLUSIONS: Increased serum CRP levels were strongly associated with worse clinical prognosis in this study.
publishDate 2012
dc.date.none.fl_str_mv 2012-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000300009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000300009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2012000300009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.70 n.3 2012
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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