Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases

Detalhes bibliográficos
Autor(a) principal: Zaidat,Osama O.
Data de Publicação: 2001
Outros Autores: Fernandes Filho,Jose Americo M., Singh,Gurwant, Suarez,Jose I.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000600018
Resumo: Extra-cranial arterial dissection accounts for 10% of strokes in young people. Information on safety of thrombolytic administration in this group is limited. The literature, however, does not favor use of thrombolytics for myocardial ischemia when peripheral arterial dissection coexists. Based on the clinical and radiological features, two patients who presented with acute stroke secondary to arterial dissection were considered for thrombolysis. One of them received intra-venous recombinant tissue plasminogen activator (rtPA), and the other patient received intra-arterial rtPA. There were no post thrombolysis complications. This report supports feasibility of administering thrombolytics in acute ischemic strokes resulting from extra-cranial arterial dissection. Future larger studies are necessary to determine the efficacy, safety and long-term outcome in this patient population.
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spelling Thrombolytic therapy for acute extra-cranial artery dissection: report of two casesthrombolysisstrokedissectioninternal carotid arteryExtra-cranial arterial dissection accounts for 10% of strokes in young people. Information on safety of thrombolytic administration in this group is limited. The literature, however, does not favor use of thrombolytics for myocardial ischemia when peripheral arterial dissection coexists. Based on the clinical and radiological features, two patients who presented with acute stroke secondary to arterial dissection were considered for thrombolysis. One of them received intra-venous recombinant tissue plasminogen activator (rtPA), and the other patient received intra-arterial rtPA. There were no post thrombolysis complications. This report supports feasibility of administering thrombolytics in acute ischemic strokes resulting from extra-cranial arterial dissection. Future larger studies are necessary to determine the efficacy, safety and long-term outcome in this patient population.Academia Brasileira de Neurologia - ABNEURO2001-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000600018Arquivos de Neuro-Psiquiatria v.59 n.4 2001reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2001000600018info:eu-repo/semantics/openAccessZaidat,Osama O.Fernandes Filho,Jose Americo M.Singh,GurwantSuarez,Jose I.eng2001-11-28T00:00:00Zoai:scielo:S0004-282X2001000600018Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2001-11-28T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
title Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
spellingShingle Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
Zaidat,Osama O.
thrombolysis
stroke
dissection
internal carotid artery
title_short Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
title_full Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
title_fullStr Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
title_full_unstemmed Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
title_sort Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases
author Zaidat,Osama O.
author_facet Zaidat,Osama O.
Fernandes Filho,Jose Americo M.
Singh,Gurwant
Suarez,Jose I.
author_role author
author2 Fernandes Filho,Jose Americo M.
Singh,Gurwant
Suarez,Jose I.
author2_role author
author
author
dc.contributor.author.fl_str_mv Zaidat,Osama O.
Fernandes Filho,Jose Americo M.
Singh,Gurwant
Suarez,Jose I.
dc.subject.por.fl_str_mv thrombolysis
stroke
dissection
internal carotid artery
topic thrombolysis
stroke
dissection
internal carotid artery
description Extra-cranial arterial dissection accounts for 10% of strokes in young people. Information on safety of thrombolytic administration in this group is limited. The literature, however, does not favor use of thrombolytics for myocardial ischemia when peripheral arterial dissection coexists. Based on the clinical and radiological features, two patients who presented with acute stroke secondary to arterial dissection were considered for thrombolysis. One of them received intra-venous recombinant tissue plasminogen activator (rtPA), and the other patient received intra-arterial rtPA. There were no post thrombolysis complications. This report supports feasibility of administering thrombolytics in acute ischemic strokes resulting from extra-cranial arterial dissection. Future larger studies are necessary to determine the efficacy, safety and long-term outcome in this patient population.
publishDate 2001
dc.date.none.fl_str_mv 2001-12-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000600018
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2001000600018
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dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.59 n.4 2001
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
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reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
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