Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS

Detalhes bibliográficos
Autor(a) principal: Koslyk,Jessyca L.
Data de Publicação: 2015
Outros Autores: Ducci,Renata D., Nóvak,Edison M., Zétola,Viviane F., Lange,Marcos C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900755
Resumo: This study analyzes the use of sodium nitroprusside (SN) as an option to reduce blood pressure (BP) below 180/105 mmHg during the management of acute ischemic stroke (AIS) in patients submitted to intravenous thrombolysis.Method The sample was composed by 60 patients who had AIS and were submitted to intravenous rtPA, split in two groups: half in the control group (CG) with BP < 180/105 mmHg and half in SN group with BP > 180/105 mmHg. Outcome variables were any hemorrhagic transformation (HT); the presence of symptomatic HT, National Institute of Health Stroke Scale (NIHSS) after 24 hours of treatment; the independence on discharge and death until three months after stroke onset.Results There were no statistical differences between both groups to any of the outcome variables analyzed.Conclusion The SN might be safe for BP control during thrombolysis to AIS.
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spelling Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AISischemic strokethrombolytic therapyhypertensionsodium nitroprussitesafetyThis study analyzes the use of sodium nitroprusside (SN) as an option to reduce blood pressure (BP) below 180/105 mmHg during the management of acute ischemic stroke (AIS) in patients submitted to intravenous thrombolysis.Method The sample was composed by 60 patients who had AIS and were submitted to intravenous rtPA, split in two groups: half in the control group (CG) with BP < 180/105 mmHg and half in SN group with BP > 180/105 mmHg. Outcome variables were any hemorrhagic transformation (HT); the presence of symptomatic HT, National Institute of Health Stroke Scale (NIHSS) after 24 hours of treatment; the independence on discharge and death until three months after stroke onset.Results There were no statistical differences between both groups to any of the outcome variables analyzed.Conclusion The SN might be safe for BP control during thrombolysis to AIS.Academia Brasileira de Neurologia - ABNEURO2015-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900755Arquivos de Neuro-Psiquiatria v.73 n.9 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150104info:eu-repo/semantics/openAccessKoslyk,Jessyca L.Ducci,Renata D.Nóvak,Edison M.Zétola,Viviane F.Lange,Marcos C.eng2015-08-31T00:00:00Zoai:scielo:S0004-282X2015000900755Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-08-31T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
title Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
spellingShingle Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
Koslyk,Jessyca L.
ischemic stroke
thrombolytic therapy
hypertension
sodium nitroprussite
safety
title_short Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
title_full Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
title_fullStr Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
title_full_unstemmed Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
title_sort Sodium nitroprusside: low price and safe drug to control BP during thrombolysis in AIS
author Koslyk,Jessyca L.
author_facet Koslyk,Jessyca L.
Ducci,Renata D.
Nóvak,Edison M.
Zétola,Viviane F.
Lange,Marcos C.
author_role author
author2 Ducci,Renata D.
Nóvak,Edison M.
Zétola,Viviane F.
Lange,Marcos C.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Koslyk,Jessyca L.
Ducci,Renata D.
Nóvak,Edison M.
Zétola,Viviane F.
Lange,Marcos C.
dc.subject.por.fl_str_mv ischemic stroke
thrombolytic therapy
hypertension
sodium nitroprussite
safety
topic ischemic stroke
thrombolytic therapy
hypertension
sodium nitroprussite
safety
description This study analyzes the use of sodium nitroprusside (SN) as an option to reduce blood pressure (BP) below 180/105 mmHg during the management of acute ischemic stroke (AIS) in patients submitted to intravenous thrombolysis.Method The sample was composed by 60 patients who had AIS and were submitted to intravenous rtPA, split in two groups: half in the control group (CG) with BP < 180/105 mmHg and half in SN group with BP > 180/105 mmHg. Outcome variables were any hemorrhagic transformation (HT); the presence of symptomatic HT, National Institute of Health Stroke Scale (NIHSS) after 24 hours of treatment; the independence on discharge and death until three months after stroke onset.Results There were no statistical differences between both groups to any of the outcome variables analyzed.Conclusion The SN might be safe for BP control during thrombolysis to AIS.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900755
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900755
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282X20150104
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.73 n.9 2015
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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