Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900770 |
Resumo: | Atypical/anaplastic (World Health Organization (WHO) grades II and III) are less common and have poorer outcomes than benign meningiomas. This study aimed to analyze the outcome of patients with these tumors.Method Overall/recurrence-free survivals (RFS) and the Karnofsky Performance Scale of 52 patients with grades II (42) and III (9) meningiomas surgically treated were analyzed (uni/multivariate analysis).Results Total/subtotal resections were 60.8%/35.3%. Patients <60 years-old and grade II tumors had longer survival. Grade II tumors, total resection andde novo meningioma had better RFS (univariate analysis). Patients >60 years-old, de novo meningioma and radiotherapy had longer survival and patients <60 years-old and with grade II tumors had longer RFS (multivariate analysis). Recurrence rate was 51% (39.2% Grade II and 66.7% Grade III). Operative mortality was 1.9%.Conclusion Age <60 years-old, grade II tumors and de novomeningiomas were the main predictors for better prognosis among patients with grades II and III meningiomas. |
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Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazilatypical and anaplastic meningiomassurgical treatmentextent of resectionsurvival curvesrecurrence survival curvesAtypical/anaplastic (World Health Organization (WHO) grades II and III) are less common and have poorer outcomes than benign meningiomas. This study aimed to analyze the outcome of patients with these tumors.Method Overall/recurrence-free survivals (RFS) and the Karnofsky Performance Scale of 52 patients with grades II (42) and III (9) meningiomas surgically treated were analyzed (uni/multivariate analysis).Results Total/subtotal resections were 60.8%/35.3%. Patients <60 years-old and grade II tumors had longer survival. Grade II tumors, total resection andde novo meningioma had better RFS (univariate analysis). Patients >60 years-old, de novo meningioma and radiotherapy had longer survival and patients <60 years-old and with grade II tumors had longer RFS (multivariate analysis). Recurrence rate was 51% (39.2% Grade II and 66.7% Grade III). Operative mortality was 1.9%.Conclusion Age <60 years-old, grade II tumors and de novomeningiomas were the main predictors for better prognosis among patients with grades II and III meningiomas.Academia Brasileira de Neurologia - ABNEURO2015-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900770Arquivos de Neuro-Psiquiatria v.73 n.9 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150106info:eu-repo/semantics/openAccessColli,Benedicto OscarCarlotti Junior,Carlos GilbertoAssirati Junior,João AlbertoCoelho Junior,Vicente de Paulo MartinsNeder,Lucianoeng2015-08-31T00:00:00Zoai:scielo:S0004-282X2015000900770Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-08-31T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
title |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
spellingShingle |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil Colli,Benedicto Oscar atypical and anaplastic meningiomas surgical treatment extent of resection survival curves recurrence survival curves |
title_short |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
title_full |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
title_fullStr |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
title_full_unstemmed |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
title_sort |
Atypical and anaplastic meningiomas in a public hospital in São Paulo State, Brazil |
author |
Colli,Benedicto Oscar |
author_facet |
Colli,Benedicto Oscar Carlotti Junior,Carlos Gilberto Assirati Junior,João Alberto Coelho Junior,Vicente de Paulo Martins Neder,Luciano |
author_role |
author |
author2 |
Carlotti Junior,Carlos Gilberto Assirati Junior,João Alberto Coelho Junior,Vicente de Paulo Martins Neder,Luciano |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Colli,Benedicto Oscar Carlotti Junior,Carlos Gilberto Assirati Junior,João Alberto Coelho Junior,Vicente de Paulo Martins Neder,Luciano |
dc.subject.por.fl_str_mv |
atypical and anaplastic meningiomas surgical treatment extent of resection survival curves recurrence survival curves |
topic |
atypical and anaplastic meningiomas surgical treatment extent of resection survival curves recurrence survival curves |
description |
Atypical/anaplastic (World Health Organization (WHO) grades II and III) are less common and have poorer outcomes than benign meningiomas. This study aimed to analyze the outcome of patients with these tumors.Method Overall/recurrence-free survivals (RFS) and the Karnofsky Performance Scale of 52 patients with grades II (42) and III (9) meningiomas surgically treated were analyzed (uni/multivariate analysis).Results Total/subtotal resections were 60.8%/35.3%. Patients <60 years-old and grade II tumors had longer survival. Grade II tumors, total resection andde novo meningioma had better RFS (univariate analysis). Patients >60 years-old, de novo meningioma and radiotherapy had longer survival and patients <60 years-old and with grade II tumors had longer RFS (multivariate analysis). Recurrence rate was 51% (39.2% Grade II and 66.7% Grade III). Operative mortality was 1.9%.Conclusion Age <60 years-old, grade II tumors and de novomeningiomas were the main predictors for better prognosis among patients with grades II and III meningiomas. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900770 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900770 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20150106 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.73 n.9 2015 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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