Alzheimer's disease and sleep disturbances: a review

Detalhes bibliográficos
Autor(a) principal: Borges,Conrado Regis
Data de Publicação: 2019
Outros Autores: Poyares,Dalva, Piovezan,Ronaldo, Nitrini,Ricardo, Brucki,Sonia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001100815
Resumo: ABSTRACT The association between Alzheimer's disease (AD) and sleep disturbances has received increasing scientific attention in the last decades. However, little is known about the impact of sleep and its disturbances on the development of preclinical AD stages, such as mild cognitive impairment. This review describes the evolution of knowledge about the potential bidirectional relationships between AD and sleep disturbances exploring recent large prospective studies and meta-analyses and studies of the possible mechanisms through which sleep and the neurodegenerative process could be associated. The review also makes a comprehensive exploration of the sleep characteristics of older people, ranging from cognitively normal individuals, through patients with mild cognitive impairment, up to the those with dementia with AD.
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spelling Alzheimer's disease and sleep disturbances: a reviewAlzheimer diseasesleep initiation and maintenance disorderscognitive dysfunctionABSTRACT The association between Alzheimer's disease (AD) and sleep disturbances has received increasing scientific attention in the last decades. However, little is known about the impact of sleep and its disturbances on the development of preclinical AD stages, such as mild cognitive impairment. This review describes the evolution of knowledge about the potential bidirectional relationships between AD and sleep disturbances exploring recent large prospective studies and meta-analyses and studies of the possible mechanisms through which sleep and the neurodegenerative process could be associated. The review also makes a comprehensive exploration of the sleep characteristics of older people, ranging from cognitively normal individuals, through patients with mild cognitive impairment, up to the those with dementia with AD.Academia Brasileira de Neurologia - ABNEURO2019-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001100815Arquivos de Neuro-Psiquiatria v.77 n.11 2019reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20190149info:eu-repo/semantics/openAccessBorges,Conrado RegisPoyares,DalvaPiovezan,RonaldoNitrini,RicardoBrucki,Soniaeng2019-12-12T00:00:00Zoai:scielo:S0004-282X2019001100815Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2019-12-12T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Alzheimer's disease and sleep disturbances: a review
title Alzheimer's disease and sleep disturbances: a review
spellingShingle Alzheimer's disease and sleep disturbances: a review
Borges,Conrado Regis
Alzheimer disease
sleep initiation and maintenance disorders
cognitive dysfunction
title_short Alzheimer's disease and sleep disturbances: a review
title_full Alzheimer's disease and sleep disturbances: a review
title_fullStr Alzheimer's disease and sleep disturbances: a review
title_full_unstemmed Alzheimer's disease and sleep disturbances: a review
title_sort Alzheimer's disease and sleep disturbances: a review
author Borges,Conrado Regis
author_facet Borges,Conrado Regis
Poyares,Dalva
Piovezan,Ronaldo
Nitrini,Ricardo
Brucki,Sonia
author_role author
author2 Poyares,Dalva
Piovezan,Ronaldo
Nitrini,Ricardo
Brucki,Sonia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Borges,Conrado Regis
Poyares,Dalva
Piovezan,Ronaldo
Nitrini,Ricardo
Brucki,Sonia
dc.subject.por.fl_str_mv Alzheimer disease
sleep initiation and maintenance disorders
cognitive dysfunction
topic Alzheimer disease
sleep initiation and maintenance disorders
cognitive dysfunction
description ABSTRACT The association between Alzheimer's disease (AD) and sleep disturbances has received increasing scientific attention in the last decades. However, little is known about the impact of sleep and its disturbances on the development of preclinical AD stages, such as mild cognitive impairment. This review describes the evolution of knowledge about the potential bidirectional relationships between AD and sleep disturbances exploring recent large prospective studies and meta-analyses and studies of the possible mechanisms through which sleep and the neurodegenerative process could be associated. The review also makes a comprehensive exploration of the sleep characteristics of older people, ranging from cognitively normal individuals, through patients with mild cognitive impairment, up to the those with dementia with AD.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001100815
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001100815
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20190149
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.77 n.11 2019
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
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institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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