Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300948 |
Resumo: | Objective To evaluate the relationship between the quantitative results of functional and cognitive performance of patients with Parkinson's disease (PD) and disease severity; and to study the relationship between patients' functional and cognitive capacity and motor impairment (Unified Parkinson's Disease Rating Scale - UPDRS III). Method Twenty-nine subjects clinically diagnosed with PD were classified into three groups according to disease severity using the modified Hoehn and Yahr Scale (H&Y). They were submitted to functional (Senior Fitness Test) and neuropsychological tests. Stepwise regression analysis showed a significant association between H&Y and upper limb strength (r 2 =0.30; p=0.005) and executive function (r 2 =0.37; p=0.004). In relation to UPDRS III, there was a significant association between lower limb strength (r 2 =0.27; p=0.010) and global cognitive status (r 2 =0.24; p=0.024). Conclusion The implementation of simple tests of functional capacity associated with neuropsychological testing can help to assess disease severity and motor impairment, and can be used to monitor the response to treatment in PD. |
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Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's diseaseParkinson's diseasecognitive functionfunctional capacityexecutive functiondisease severity Objective To evaluate the relationship between the quantitative results of functional and cognitive performance of patients with Parkinson's disease (PD) and disease severity; and to study the relationship between patients' functional and cognitive capacity and motor impairment (Unified Parkinson's Disease Rating Scale - UPDRS III). Method Twenty-nine subjects clinically diagnosed with PD were classified into three groups according to disease severity using the modified Hoehn and Yahr Scale (H&Y). They were submitted to functional (Senior Fitness Test) and neuropsychological tests. Stepwise regression analysis showed a significant association between H&Y and upper limb strength (r 2 =0.30; p=0.005) and executive function (r 2 =0.37; p=0.004). In relation to UPDRS III, there was a significant association between lower limb strength (r 2 =0.27; p=0.010) and global cognitive status (r 2 =0.24; p=0.024). Conclusion The implementation of simple tests of functional capacity associated with neuropsychological testing can help to assess disease severity and motor impairment, and can be used to monitor the response to treatment in PD. Academia Brasileira de Neurologia - ABNEURO2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300948Arquivos de Neuro-Psiquiatria v.71 n.12 2013reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20130175info:eu-repo/semantics/openAccessBarbirato,DannyelCarvalho,AlessandroAraujo,Narahyana Bom deMartins,Jose VicenteDeslandes,Andreaeng2013-12-13T00:00:00Zoai:scielo:S0004-282X2013001300948Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2013-12-13T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
title |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
spellingShingle |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease Barbirato,Dannyel Parkinson's disease cognitive function functional capacity executive function disease severity |
title_short |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
title_full |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
title_fullStr |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
title_full_unstemmed |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
title_sort |
Muscle strength and executive function as complementary parameters for the assessment of impairment in Parkinson's disease |
author |
Barbirato,Dannyel |
author_facet |
Barbirato,Dannyel Carvalho,Alessandro Araujo,Narahyana Bom de Martins,Jose Vicente Deslandes,Andrea |
author_role |
author |
author2 |
Carvalho,Alessandro Araujo,Narahyana Bom de Martins,Jose Vicente Deslandes,Andrea |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barbirato,Dannyel Carvalho,Alessandro Araujo,Narahyana Bom de Martins,Jose Vicente Deslandes,Andrea |
dc.subject.por.fl_str_mv |
Parkinson's disease cognitive function functional capacity executive function disease severity |
topic |
Parkinson's disease cognitive function functional capacity executive function disease severity |
description |
Objective To evaluate the relationship between the quantitative results of functional and cognitive performance of patients with Parkinson's disease (PD) and disease severity; and to study the relationship between patients' functional and cognitive capacity and motor impairment (Unified Parkinson's Disease Rating Scale - UPDRS III). Method Twenty-nine subjects clinically diagnosed with PD were classified into three groups according to disease severity using the modified Hoehn and Yahr Scale (H&Y). They were submitted to functional (Senior Fitness Test) and neuropsychological tests. Stepwise regression analysis showed a significant association between H&Y and upper limb strength (r 2 =0.30; p=0.005) and executive function (r 2 =0.37; p=0.004). In relation to UPDRS III, there was a significant association between lower limb strength (r 2 =0.27; p=0.010) and global cognitive status (r 2 =0.24; p=0.024). Conclusion The implementation of simple tests of functional capacity associated with neuropsychological testing can help to assess disease severity and motor impairment, and can be used to monitor the response to treatment in PD. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300948 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300948 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20130175 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.71 n.12 2013 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212775396114432 |