CT hypodensity on cerebral white matter in Wilson's disease
Autor(a) principal: | |
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Data de Publicação: | 1991 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1991000200017 |
Resumo: | Wilson's disease in an autosomal recessive disorder of copper metabolism where systemic manifestations are secondary to thei accumulation of copper in hepatic, nervous and other tissues. In CNS, the structural lesions most commonly found by CT scan are ventricular dilatation, cortical atrophy, basal ganglia hyperdensities, and brainstem and cerebellar atrophy. Degenerative changes of cerebral white matter seen on early anatomo-pathologic studies, but were almost never found on CT scan from recently described patients. We report a case of Wilson's disease with an unusually rapid deterioration where asymmetric low-densities in the subcortical white matter were disclosed by CT scan. |
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CT hypodensity on cerebral white matter in Wilson's diseaseWilson's disease in an autosomal recessive disorder of copper metabolism where systemic manifestations are secondary to thei accumulation of copper in hepatic, nervous and other tissues. In CNS, the structural lesions most commonly found by CT scan are ventricular dilatation, cortical atrophy, basal ganglia hyperdensities, and brainstem and cerebellar atrophy. Degenerative changes of cerebral white matter seen on early anatomo-pathologic studies, but were almost never found on CT scan from recently described patients. We report a case of Wilson's disease with an unusually rapid deterioration where asymmetric low-densities in the subcortical white matter were disclosed by CT scan.Academia Brasileira de Neurologia - ABNEURO1991-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1991000200017Arquivos de Neuro-Psiquiatria v.49 n.2 1991reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1991000200017info:eu-repo/semantics/openAccessJardim,Laura B.Carneiro,AníbalHansel,SuzanaRieder,Carlos R. M.Giugliani,Robertoeng2011-02-22T00:00:00Zoai:scielo:S0004-282X1991000200017Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2011-02-22T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
CT hypodensity on cerebral white matter in Wilson's disease |
title |
CT hypodensity on cerebral white matter in Wilson's disease |
spellingShingle |
CT hypodensity on cerebral white matter in Wilson's disease Jardim,Laura B. |
title_short |
CT hypodensity on cerebral white matter in Wilson's disease |
title_full |
CT hypodensity on cerebral white matter in Wilson's disease |
title_fullStr |
CT hypodensity on cerebral white matter in Wilson's disease |
title_full_unstemmed |
CT hypodensity on cerebral white matter in Wilson's disease |
title_sort |
CT hypodensity on cerebral white matter in Wilson's disease |
author |
Jardim,Laura B. |
author_facet |
Jardim,Laura B. Carneiro,Aníbal Hansel,Suzana Rieder,Carlos R. M. Giugliani,Roberto |
author_role |
author |
author2 |
Carneiro,Aníbal Hansel,Suzana Rieder,Carlos R. M. Giugliani,Roberto |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Jardim,Laura B. Carneiro,Aníbal Hansel,Suzana Rieder,Carlos R. M. Giugliani,Roberto |
description |
Wilson's disease in an autosomal recessive disorder of copper metabolism where systemic manifestations are secondary to thei accumulation of copper in hepatic, nervous and other tissues. In CNS, the structural lesions most commonly found by CT scan are ventricular dilatation, cortical atrophy, basal ganglia hyperdensities, and brainstem and cerebellar atrophy. Degenerative changes of cerebral white matter seen on early anatomo-pathologic studies, but were almost never found on CT scan from recently described patients. We report a case of Wilson's disease with an unusually rapid deterioration where asymmetric low-densities in the subcortical white matter were disclosed by CT scan. |
publishDate |
1991 |
dc.date.none.fl_str_mv |
1991-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1991000200017 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1991000200017 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X1991000200017 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.49 n.2 1991 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
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