Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764 |
Resumo: | Over the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly patients with non-functioning pituitary macroadenoma (NFPM) operated by the endoscopic endonasal approach (EEA). Preoperative visual loss was found in 92.8% of the cases, and 70.8% experienced visual improvement following surgery. Preoperative pituitary dysfunction was found in 69.2% of the cases and postoperative pituitary recovery occurred in 22.2% of them. Mean hospital stay was 6.7 days. The results of this study suggest that surgery remains the first line of treatment for NFPM in the elderly. Because age alone is not a barrier for surgery, patients should be selected for surgical treatment based on their symptoms and clinical condition, as defined by comorbidities. |
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Arquivos de neuro-psiquiatria (Online) |
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Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderlyagedpituitary neoplasmspituitary diseasesendoscopic surgical proceduresOver the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly patients with non-functioning pituitary macroadenoma (NFPM) operated by the endoscopic endonasal approach (EEA). Preoperative visual loss was found in 92.8% of the cases, and 70.8% experienced visual improvement following surgery. Preoperative pituitary dysfunction was found in 69.2% of the cases and postoperative pituitary recovery occurred in 22.2% of them. Mean hospital stay was 6.7 days. The results of this study suggest that surgery remains the first line of treatment for NFPM in the elderly. Because age alone is not a barrier for surgery, patients should be selected for surgical treatment based on their symptoms and clinical condition, as defined by comorbidities.Academia Brasileira de Neurologia - ABNEURO2015-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764Arquivos de Neuro-Psiquiatria v.73 n.9 2015reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20150112info:eu-repo/semantics/openAccessMarenco,Horacio ArmandoZymberg,Samuel TauSantos,Rodrigo de PaulaRamalho,Cláuder Oliveiraeng2015-08-31T00:00:00Zoai:scielo:S0004-282X2015000900764Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2015-08-31T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
title |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
spellingShingle |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly Marenco,Horacio Armando aged pituitary neoplasms pituitary diseases endoscopic surgical procedures |
title_short |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
title_full |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
title_fullStr |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
title_full_unstemmed |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
title_sort |
Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
author |
Marenco,Horacio Armando |
author_facet |
Marenco,Horacio Armando Zymberg,Samuel Tau Santos,Rodrigo de Paula Ramalho,Cláuder Oliveira |
author_role |
author |
author2 |
Zymberg,Samuel Tau Santos,Rodrigo de Paula Ramalho,Cláuder Oliveira |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Marenco,Horacio Armando Zymberg,Samuel Tau Santos,Rodrigo de Paula Ramalho,Cláuder Oliveira |
dc.subject.por.fl_str_mv |
aged pituitary neoplasms pituitary diseases endoscopic surgical procedures |
topic |
aged pituitary neoplasms pituitary diseases endoscopic surgical procedures |
description |
Over the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly patients with non-functioning pituitary macroadenoma (NFPM) operated by the endoscopic endonasal approach (EEA). Preoperative visual loss was found in 92.8% of the cases, and 70.8% experienced visual improvement following surgery. Preoperative pituitary dysfunction was found in 69.2% of the cases and postoperative pituitary recovery occurred in 22.2% of them. Mean hospital stay was 6.7 days. The results of this study suggest that surgery remains the first line of treatment for NFPM in the elderly. Because age alone is not a barrier for surgery, patients should be selected for surgical treatment based on their symptoms and clinical condition, as defined by comorbidities. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20150112 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.73 n.9 2015 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212778595319808 |