Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600451 |
Resumo: | Spinal cord injury (SCI) and amyotrophic laterals sclerosis (ALS) are devastating neurological conditions that affect individuals worldwide, significantly reducing quality of life, both for patients and their relatives. Objective : The present review aims to summarize the multiple restorative approaches being developed for spinal cord repair, the use of different stem cell types and the current knowledge regarding stem cell therapy. Method : Review of the literature from the past 10 years of human studies using stem cell transplantation as the main therapy, with or without adjuvant therapies. Conclusion : The current review offers an overview of the state of the art regarding spinal cord restoration, and serves as a starting point for future studies. |
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Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 yearsspinal cord injuryamyotrophic lateral sclerosisstem cellsstem cell therapySpinal cord injury (SCI) and amyotrophic laterals sclerosis (ALS) are devastating neurological conditions that affect individuals worldwide, significantly reducing quality of life, both for patients and their relatives. Objective : The present review aims to summarize the multiple restorative approaches being developed for spinal cord repair, the use of different stem cell types and the current knowledge regarding stem cell therapy. Method : Review of the literature from the past 10 years of human studies using stem cell transplantation as the main therapy, with or without adjuvant therapies. Conclusion : The current review offers an overview of the state of the art regarding spinal cord restoration, and serves as a starting point for future studies. Academia Brasileira de Neurologia - ABNEURO2014-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600451Arquivos de Neuro-Psiquiatria v.72 n.6 2014reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20140051info:eu-repo/semantics/openAccessMariano,Eric DomingosBatista,Chary MarquezBarbosa,Breno José Alencar PiresMarie,Suely Kazue NagahashiTeixeira,Manoel JacobsenMorgalla,MatthiasTatagiba,MarcosLi,JunLepski,Guilhermeeng2014-06-16T00:00:00Zoai:scielo:S0004-282X2014000600451Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2014-06-16T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
title |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
spellingShingle |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years Mariano,Eric Domingos spinal cord injury amyotrophic lateral sclerosis stem cells stem cell therapy |
title_short |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
title_full |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
title_fullStr |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
title_full_unstemmed |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
title_sort |
Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years |
author |
Mariano,Eric Domingos |
author_facet |
Mariano,Eric Domingos Batista,Chary Marquez Barbosa,Breno José Alencar Pires Marie,Suely Kazue Nagahashi Teixeira,Manoel Jacobsen Morgalla,Matthias Tatagiba,Marcos Li,Jun Lepski,Guilherme |
author_role |
author |
author2 |
Batista,Chary Marquez Barbosa,Breno José Alencar Pires Marie,Suely Kazue Nagahashi Teixeira,Manoel Jacobsen Morgalla,Matthias Tatagiba,Marcos Li,Jun Lepski,Guilherme |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Mariano,Eric Domingos Batista,Chary Marquez Barbosa,Breno José Alencar Pires Marie,Suely Kazue Nagahashi Teixeira,Manoel Jacobsen Morgalla,Matthias Tatagiba,Marcos Li,Jun Lepski,Guilherme |
dc.subject.por.fl_str_mv |
spinal cord injury amyotrophic lateral sclerosis stem cells stem cell therapy |
topic |
spinal cord injury amyotrophic lateral sclerosis stem cells stem cell therapy |
description |
Spinal cord injury (SCI) and amyotrophic laterals sclerosis (ALS) are devastating neurological conditions that affect individuals worldwide, significantly reducing quality of life, both for patients and their relatives. Objective : The present review aims to summarize the multiple restorative approaches being developed for spinal cord repair, the use of different stem cell types and the current knowledge regarding stem cell therapy. Method : Review of the literature from the past 10 years of human studies using stem cell transplantation as the main therapy, with or without adjuvant therapies. Conclusion : The current review offers an overview of the state of the art regarding spinal cord restoration, and serves as a starting point for future studies. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600451 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000600451 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20140051 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.72 n.6 2014 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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