Conjugal amyotrophic lateral sclerosis in Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000600015 |
Resumo: | The origin of amyotrophic lateral sclerosis (ALS) remains unknown, although it seems to be multifactorial. The role of environmental factors has been frequently investigated and suspicion of its influence can be obtained when clusters of a rare disease are described. OBJECTIVE: To describe conjugal cases of ALS in Brazil. METHOD: We describe 2 couples in which both spouses were affected by ALS. Both couples had lived in southeast Brazil and were married for at least 20 years. RESULTS: There was a great variability in clinical presentation of ALS in our patients. In both couples the interval between disease onsets was short. No precise environmental factors could be identified at the origin of these conjugal cases. CONCLUSION: The occurrence of ALS in couples living in the same area may be epidemiologically important, but we cannot exclude that cases may be due to a chance association. |
id |
ABNEURO-1_f50a923488deab4869053e8dd059e5ef |
---|---|
oai_identifier_str |
oai:scielo:S0004-282X2009000600015 |
network_acronym_str |
ABNEURO-1 |
network_name_str |
Arquivos de neuro-psiquiatria (Online) |
repository_id_str |
|
spelling |
Conjugal amyotrophic lateral sclerosis in Brazilamyotrophic lateral sclerosisconjugalenvironmental factorsetiologyThe origin of amyotrophic lateral sclerosis (ALS) remains unknown, although it seems to be multifactorial. The role of environmental factors has been frequently investigated and suspicion of its influence can be obtained when clusters of a rare disease are described. OBJECTIVE: To describe conjugal cases of ALS in Brazil. METHOD: We describe 2 couples in which both spouses were affected by ALS. Both couples had lived in southeast Brazil and were married for at least 20 years. RESULTS: There was a great variability in clinical presentation of ALS in our patients. In both couples the interval between disease onsets was short. No precise environmental factors could be identified at the origin of these conjugal cases. CONCLUSION: The occurrence of ALS in couples living in the same area may be epidemiologically important, but we cannot exclude that cases may be due to a chance association.Academia Brasileira de Neurologia - ABNEURO2009-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000600015Arquivos de Neuro-Psiquiatria v.67 n.4 2009reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2009000600015info:eu-repo/semantics/openAccessGodeiro-Junior,ClecioOliveira,Acary S.B.Felicio,Andre C.Chieia,Marco A.Gabbai,Alberto Alaineng2009-12-16T00:00:00Zoai:scielo:S0004-282X2009000600015Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2009-12-16T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Conjugal amyotrophic lateral sclerosis in Brazil |
title |
Conjugal amyotrophic lateral sclerosis in Brazil |
spellingShingle |
Conjugal amyotrophic lateral sclerosis in Brazil Godeiro-Junior,Clecio amyotrophic lateral sclerosis conjugal environmental factors etiology |
title_short |
Conjugal amyotrophic lateral sclerosis in Brazil |
title_full |
Conjugal amyotrophic lateral sclerosis in Brazil |
title_fullStr |
Conjugal amyotrophic lateral sclerosis in Brazil |
title_full_unstemmed |
Conjugal amyotrophic lateral sclerosis in Brazil |
title_sort |
Conjugal amyotrophic lateral sclerosis in Brazil |
author |
Godeiro-Junior,Clecio |
author_facet |
Godeiro-Junior,Clecio Oliveira,Acary S.B. Felicio,Andre C. Chieia,Marco A. Gabbai,Alberto Alain |
author_role |
author |
author2 |
Oliveira,Acary S.B. Felicio,Andre C. Chieia,Marco A. Gabbai,Alberto Alain |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Godeiro-Junior,Clecio Oliveira,Acary S.B. Felicio,Andre C. Chieia,Marco A. Gabbai,Alberto Alain |
dc.subject.por.fl_str_mv |
amyotrophic lateral sclerosis conjugal environmental factors etiology |
topic |
amyotrophic lateral sclerosis conjugal environmental factors etiology |
description |
The origin of amyotrophic lateral sclerosis (ALS) remains unknown, although it seems to be multifactorial. The role of environmental factors has been frequently investigated and suspicion of its influence can be obtained when clusters of a rare disease are described. OBJECTIVE: To describe conjugal cases of ALS in Brazil. METHOD: We describe 2 couples in which both spouses were affected by ALS. Both couples had lived in southeast Brazil and were married for at least 20 years. RESULTS: There was a great variability in clinical presentation of ALS in our patients. In both couples the interval between disease onsets was short. No precise environmental factors could be identified at the origin of these conjugal cases. CONCLUSION: The occurrence of ALS in couples living in the same area may be epidemiologically important, but we cannot exclude that cases may be due to a chance association. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000600015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000600015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2009000600015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.67 n.4 2009 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212767538085888 |