Analysis of drug interactions in dental prescriptions.

Detalhes bibliográficos
Autor(a) principal: Furini, Adriana Antônia da Cruz
Data de Publicação: 2018
Outros Autores: Malagoli, Juliana Mendes de Almeida, Dias, Nayane Justi, Lima, Bruna Miranda, Bonjardin, Manuela Manzano, Machado, Ponatyellen Souza, Lima, Tiago Aparecido Maschio de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Odontologia
Texto Completo: https://revista.aborj.org.br/index.php/rbo/article/view/1021
Resumo: Objective: to evaluate the potential drug interactions (DI) in prescriptions for patients of a private university’s dental clinic. Material and Methods: this is an exploratory descriptive study. A total of 204 dental prescriptions were analyzed between April 2015 and October 2016. The databases for the analysis of DI potential wereaccessed through the programs Medscape, Drugs.com and Micromedex.The DIs were classified by intensity in major, moderate and minor. Results: the mean age was 43 ± 14 years old and 61% of the participants were female. Hypertension and Type II diabetes were the most prevalent diseases. 237 non-steroidal anti-inflammatory drugs were prescribed, with nimesulide being the most prevalent in the prescriptions, followed by dipyrone with analgesic and antipyretic effect. Of these, eighty-nine were antimicrobials, mostly amoxicillin. We identified 95 potential drug interactions, 28% being of major intensity and 67% of moderate intensity. Twelve interactions involved non-steroidal anti-inflammatory drugs, mainly ketoprofen, diclofenac and ibuprofen; and nine were related to the antimicrobials amoxicillin, metronizadol and azithromycin. Conclusion: The need for a careful analysis of dental prescriptions and a review of the concomitant therapy used by patients, reducing the risk of interactions, and consequently, preventing adverse reactions and preserving the patients’ safety, are observed.
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spelling Analysis of drug interactions in dental prescriptions.Análise de interações medicamentosas em prescrições dentáriasPHARMACOLOGYDrug Interactions; Dentistry; Non-steroidal anti-inflammatory drugs; Anti-Infectious.MEDICINA DENTÁRIA (ODONTOLOGIA)Interações medicamentosas; Odontologia; Anti-inflamatórios não esteróides; Anti-infecciosoObjective: to evaluate the potential drug interactions (DI) in prescriptions for patients of a private university’s dental clinic. Material and Methods: this is an exploratory descriptive study. A total of 204 dental prescriptions were analyzed between April 2015 and October 2016. The databases for the analysis of DI potential wereaccessed through the programs Medscape, Drugs.com and Micromedex.The DIs were classified by intensity in major, moderate and minor. Results: the mean age was 43 ± 14 years old and 61% of the participants were female. Hypertension and Type II diabetes were the most prevalent diseases. 237 non-steroidal anti-inflammatory drugs were prescribed, with nimesulide being the most prevalent in the prescriptions, followed by dipyrone with analgesic and antipyretic effect. Of these, eighty-nine were antimicrobials, mostly amoxicillin. We identified 95 potential drug interactions, 28% being of major intensity and 67% of moderate intensity. Twelve interactions involved non-steroidal anti-inflammatory drugs, mainly ketoprofen, diclofenac and ibuprofen; and nine were related to the antimicrobials amoxicillin, metronizadol and azithromycin. Conclusion: The need for a careful analysis of dental prescriptions and a review of the concomitant therapy used by patients, reducing the risk of interactions, and consequently, preventing adverse reactions and preserving the patients’ safety, are observed.Objetivo: avaliar as interações medicamentosas potenciais (DI) em prescrições para pacientes de clínica odontológica de uma universidade privada. Material e Métodos: trata-se de um estudo exploratório descritivo. Foram analisadas 204 prescrições odontológicas entre abril de 2015 e outubro de 2016. As bases de dados para a análise do potencial de DI foram acessadas pelos programas Medscape, Drugs.com e Micromedex. Os DIs foram classificados por intensidade em maior, moderada e menor. Resultados: a média de idade foi de 43 ± 14 anos e 61% dos participantes eram do sexo feminino. Hipertensão e diabetes tipo II foram as doenças mais prevalentes. 237 anti-inflamatórios não esteroidais foram prescritos, sendo a nimesulida a mais prevalente nas prescrições, seguida da dipirona com efeito analgésico e antipirético. Destes, oitenta e nove eram antimicrobianos, principalmente amoxicilina. Foram identificadas 95 interações medicamentosas potenciais, sendo 28% de maior intensidade e 67% de intensidade moderada. Doze interações envolveram drogas antiinflamatórias não esteroidais, principalmente cetoprofeno, diclofenaco e ibuprofeno; e nove foram relacionados aos antimicrobianos amoxicilina, metronizadol e azitromicina. Conclusão: A necessidade de uma análise cuidadosa das prescrições dentárias e uma revisão da terapia concomitante utilizada pelos pacientes, reduzindo o risco de interações e, conseqüentemente, prevenindo reações adversas e preservando a segurança dos pacientes, são observadas.Associação Brasileira de Odontologia - Seção Rio de JaneiroFurini, Adriana Antônia da CruzMalagoli, Juliana Mendes de AlmeidaDias, Nayane JustiLima, Bruna MirandaBonjardin, Manuela ManzanoMachado, Ponatyellen SouzaLima, Tiago Aparecido Maschio de2018-07-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionOriginal ArticleArtigo Originalapplication/pdfhttps://revista.aborj.org.br/index.php/rbo/article/view/102110.18363/rbo.v75.2018.e1021Revista Brasileira de Odontologia; v. 75 (2018); 1/6Revista Brasileira de Odontologia; v. 75 (2018); 1/61984-3747reponame:Revista Brasileira de Odontologiainstname:Associação Brasileira de Odontologia (ABO)instacron:ABOenghttps://revista.aborj.org.br/index.php/rbo/article/view/1021/682https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1306https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1307https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1308São José do Rio Preto; BrazilModernby sexSão José do Rio Preto; BrasilModernapor sexoDireitos autorais 2018 Rev. Bras. Odontol.http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess2019-08-06T15:46:42Zoai:revista_aborj_org_br.www.revista.aborj.org.br:article/1021Revistahttps://revista.aborj.org.br/index.php/rboONGhttp://www.revista.aborj.org.br/index.php/rbo/oaihttps://revista.aborj.org.br/index.php/rbo/oai0034-72721984-3747opendoar:2019-08-06T15:46:42Revista Brasileira de Odontologia - Associação Brasileira de Odontologia (ABO)false
dc.title.none.fl_str_mv Analysis of drug interactions in dental prescriptions.
Análise de interações medicamentosas em prescrições dentárias
title Analysis of drug interactions in dental prescriptions.
spellingShingle Analysis of drug interactions in dental prescriptions.
Furini, Adriana Antônia da Cruz
PHARMACOLOGY
Drug Interactions; Dentistry; Non-steroidal anti-inflammatory drugs; Anti-Infectious.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Interações medicamentosas; Odontologia; Anti-inflamatórios não esteróides; Anti-infeccioso
title_short Analysis of drug interactions in dental prescriptions.
title_full Analysis of drug interactions in dental prescriptions.
title_fullStr Analysis of drug interactions in dental prescriptions.
title_full_unstemmed Analysis of drug interactions in dental prescriptions.
title_sort Analysis of drug interactions in dental prescriptions.
author Furini, Adriana Antônia da Cruz
author_facet Furini, Adriana Antônia da Cruz
Malagoli, Juliana Mendes de Almeida
Dias, Nayane Justi
Lima, Bruna Miranda
Bonjardin, Manuela Manzano
Machado, Ponatyellen Souza
Lima, Tiago Aparecido Maschio de
author_role author
author2 Malagoli, Juliana Mendes de Almeida
Dias, Nayane Justi
Lima, Bruna Miranda
Bonjardin, Manuela Manzano
Machado, Ponatyellen Souza
Lima, Tiago Aparecido Maschio de
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv

dc.contributor.author.fl_str_mv Furini, Adriana Antônia da Cruz
Malagoli, Juliana Mendes de Almeida
Dias, Nayane Justi
Lima, Bruna Miranda
Bonjardin, Manuela Manzano
Machado, Ponatyellen Souza
Lima, Tiago Aparecido Maschio de
dc.subject.none.fl_str_mv

dc.subject.por.fl_str_mv PHARMACOLOGY
Drug Interactions; Dentistry; Non-steroidal anti-inflammatory drugs; Anti-Infectious.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Interações medicamentosas; Odontologia; Anti-inflamatórios não esteróides; Anti-infeccioso
topic PHARMACOLOGY
Drug Interactions; Dentistry; Non-steroidal anti-inflammatory drugs; Anti-Infectious.
MEDICINA DENTÁRIA (ODONTOLOGIA)
Interações medicamentosas; Odontologia; Anti-inflamatórios não esteróides; Anti-infeccioso
description Objective: to evaluate the potential drug interactions (DI) in prescriptions for patients of a private university’s dental clinic. Material and Methods: this is an exploratory descriptive study. A total of 204 dental prescriptions were analyzed between April 2015 and October 2016. The databases for the analysis of DI potential wereaccessed through the programs Medscape, Drugs.com and Micromedex.The DIs were classified by intensity in major, moderate and minor. Results: the mean age was 43 ± 14 years old and 61% of the participants were female. Hypertension and Type II diabetes were the most prevalent diseases. 237 non-steroidal anti-inflammatory drugs were prescribed, with nimesulide being the most prevalent in the prescriptions, followed by dipyrone with analgesic and antipyretic effect. Of these, eighty-nine were antimicrobials, mostly amoxicillin. We identified 95 potential drug interactions, 28% being of major intensity and 67% of moderate intensity. Twelve interactions involved non-steroidal anti-inflammatory drugs, mainly ketoprofen, diclofenac and ibuprofen; and nine were related to the antimicrobials amoxicillin, metronizadol and azithromycin. Conclusion: The need for a careful analysis of dental prescriptions and a review of the concomitant therapy used by patients, reducing the risk of interactions, and consequently, preventing adverse reactions and preserving the patients’ safety, are observed.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-26
dc.type.none.fl_str_mv

dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://revista.aborj.org.br/index.php/rbo/article/view/1021
10.18363/rbo.v75.2018.e1021
url https://revista.aborj.org.br/index.php/rbo/article/view/1021
identifier_str_mv 10.18363/rbo.v75.2018.e1021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revista.aborj.org.br/index.php/rbo/article/view/1021/682
https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1306
https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1307
https://revista.aborj.org.br/index.php/rbo/article/downloadSuppFile/1021/1308
dc.rights.driver.fl_str_mv Direitos autorais 2018 Rev. Bras. Odontol.
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos autorais 2018 Rev. Bras. Odontol.
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv São José do Rio Preto; Brazil
Modern
by sex
São José do Rio Preto; Brasil
Moderna
por sexo
dc.publisher.none.fl_str_mv Associação Brasileira de Odontologia - Seção Rio de Janeiro
publisher.none.fl_str_mv Associação Brasileira de Odontologia - Seção Rio de Janeiro
dc.source.none.fl_str_mv Revista Brasileira de Odontologia; v. 75 (2018); 1/6
Revista Brasileira de Odontologia; v. 75 (2018); 1/6
1984-3747
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repository.name.fl_str_mv Revista Brasileira de Odontologia - Associação Brasileira de Odontologia (ABO)
repository.mail.fl_str_mv https://revista.aborj.org.br/index.php/rbo/oai
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