Chitosan/D. ambrosioides (mastruz) spheres to be applied as a biomaterial

• Autor(a) principal: Medeiros, Luanna Abilio Diniz Melquiades de
• Data de Publicação: 2016
• Outros Autores: Barbosa, Rossemberg Cardoso, Rosendo, Rosana Araújo, Oliveira, Dayanna Kelly Marques de, Viana, Fernando Antônio Cavalcanti, Fook, Marcus Vinícius Lia
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Brasileira de Odontologia
• Texto Completo: https://revista.aborj.org.br/index.php/rbo/article/view/644
• topic: Chitosan; Medicinal plants; Bone regeneration; MEDICINA DENTÁRIA (ODONTOLOGIA); Quitosana; Plantas medicinais; Regeneração óssea; Biomateriais

Objective: This worked aimed to develop chitosan/D. ambrosioides (mastruz) spheres to be applied as a biomaterial. Material and Methods: To obtain the chitosan spheres and the chitosan with crude ethanolic extract of mastruz (CEE) the Ionotropic gelation technique was used. Four groups were formed: QO- Chitosan; Q5; Q10 and Q20, Chitosan with 5%, 10% and 20% of CEE, respectively. Were characterized by Optic Microscopy (OM); Cytotoxicity and Biodegradation.Results: InOM, well delimited and darker spheres were observed, as the CEE percentage increased. All groups were noncytotoxic. In the presence of lysozyme, mass loss was observed, as for in solution Phosphate Buffered Saline (PBS) the mass gain was found. Conclusion: It can be concluded that the spheres presented potential for use as a biomaterial.