Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Otorhinolaryngology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942020000500545 |
Resumo: | Abstract Introduction: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. Objective: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. Methods: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. Results: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. Conclusion: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months. |
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Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomyOropharyngeal neoplasmsGlossectomyOral neoplasmsSurvival analysisPhysiological function recoveryAbstract Introduction: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. Objective: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. Methods: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. Results: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. Conclusion: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2020-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942020000500545Brazilian Journal of Otorhinolaryngology v.86 n.5 2020reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1016/j.bjorl.2019.02.005info:eu-repo/semantics/openAccessQuinsan,Isabela de Cássia MarinsCosta,Gustavo CarvalhoPriante,Antonio Vitor MartinsCardoso,Cesar AugustoNunes,Caio Lúcio Soubhiaeng2020-11-05T00:00:00Zoai:scielo:S1808-86942020000500545Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2020-11-05T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false |
dc.title.none.fl_str_mv |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
title |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
spellingShingle |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy Quinsan,Isabela de Cássia Marins Oropharyngeal neoplasms Glossectomy Oral neoplasms Survival analysis Physiological function recovery |
title_short |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
title_full |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
title_fullStr |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
title_full_unstemmed |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
title_sort |
Functional outcomes and survival of patients with oral and oropharyngeal cancer after total glossectomy |
author |
Quinsan,Isabela de Cássia Marins |
author_facet |
Quinsan,Isabela de Cássia Marins Costa,Gustavo Carvalho Priante,Antonio Vitor Martins Cardoso,Cesar Augusto Nunes,Caio Lúcio Soubhia |
author_role |
author |
author2 |
Costa,Gustavo Carvalho Priante,Antonio Vitor Martins Cardoso,Cesar Augusto Nunes,Caio Lúcio Soubhia |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Quinsan,Isabela de Cássia Marins Costa,Gustavo Carvalho Priante,Antonio Vitor Martins Cardoso,Cesar Augusto Nunes,Caio Lúcio Soubhia |
dc.subject.por.fl_str_mv |
Oropharyngeal neoplasms Glossectomy Oral neoplasms Survival analysis Physiological function recovery |
topic |
Oropharyngeal neoplasms Glossectomy Oral neoplasms Survival analysis Physiological function recovery |
description |
Abstract Introduction: Cancer of the oral cavity and oropharynx presents aggressive behavior and its diagnosis is, in most cases, performed in advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only one in the recurrent or residual disease, after chemoradiotherapy. Objective: To evaluate the clinical-epidemiological profile, postoperative complications, survival rates and functional aspects of patients with oral cavity and oropharynx cancer after total glossectomy. Methods: It was a retrospective study where 22 patients were included with oral cavity and oropharyngeal cancer after total glossectomy at the Hospital Regional do Vale do Paraíba, em Taubaté, São Paulo. Results: All patients were male, with a median age of 57 years, most of tumors are located in the tongue and floor of the mouth and classified as stage IVa. Total glossectomy as initial treatment was performed in 18 and as salvage in four patients. The major pectoralis myocutaneous flap was used for reconstruction in all cases. The main postoperative complication was wound infection and salivary fistula. Conclusion: Overall survival was 19% and cancer-specific survival was 30.8% in five years. Eight patients were rehabilitated for exclusive oral feeding without the dependence tracheostomy and enteral tube, all with an overall survival greater than 15 months. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942020000500545 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942020000500545 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjorl.2019.02.005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
publisher.none.fl_str_mv |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
dc.source.none.fl_str_mv |
Brazilian Journal of Otorhinolaryngology v.86 n.5 2020 reponame:Brazilian Journal of Otorhinolaryngology instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) instacron:ABORL-CCF |
instname_str |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) |
instacron_str |
ABORL-CCF |
institution |
ABORL-CCF |
reponame_str |
Brazilian Journal of Otorhinolaryngology |
collection |
Brazilian Journal of Otorhinolaryngology |
repository.name.fl_str_mv |
Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) |
repository.mail.fl_str_mv |
revista@aborlccf.org.br||revista@aborlccf.org.br |
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1754575994082033664 |