Assessment of mucosal changes associated with nasal splint in a rabbit model

Detalhes bibliográficos
Autor(a) principal: Tan,Mehmet
Data de Publicação: 2015
Outros Autores: Kalcioglu,M. Tayyar, Sahin,Nurhan, Bayindir,Tuba, Samdanci,Emine, Filiz,Aliye
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000200184
Resumo: INTRODUCTION: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation.OBJECTIVES: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model.METHODS: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored.RESULTS: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D.CONCLUSIONS: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations.
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spelling Assessment of mucosal changes associated with nasal splint in a rabbit modelNasal mucosaNasal septal perforationNasal septumTampons surgicalINTRODUCTION: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation.OBJECTIVES: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model.METHODS: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored.RESULTS: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D.CONCLUSIONS: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2015-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000200184Brazilian Journal of Otorhinolaryngology v.81 n.2 2015reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1016/j.bjorl.2014.08.004info:eu-repo/semantics/openAccessTan,MehmetKalcioglu,M. TayyarSahin,NurhanBayindir,TubaSamdanci,EmineFiliz,Aliyeeng2015-10-26T00:00:00Zoai:scielo:S1808-86942015000200184Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2015-10-26T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false
dc.title.none.fl_str_mv Assessment of mucosal changes associated with nasal splint in a rabbit model
title Assessment of mucosal changes associated with nasal splint in a rabbit model
spellingShingle Assessment of mucosal changes associated with nasal splint in a rabbit model
Tan,Mehmet
Nasal mucosa
Nasal septal perforation
Nasal septum
Tampons surgical
title_short Assessment of mucosal changes associated with nasal splint in a rabbit model
title_full Assessment of mucosal changes associated with nasal splint in a rabbit model
title_fullStr Assessment of mucosal changes associated with nasal splint in a rabbit model
title_full_unstemmed Assessment of mucosal changes associated with nasal splint in a rabbit model
title_sort Assessment of mucosal changes associated with nasal splint in a rabbit model
author Tan,Mehmet
author_facet Tan,Mehmet
Kalcioglu,M. Tayyar
Sahin,Nurhan
Bayindir,Tuba
Samdanci,Emine
Filiz,Aliye
author_role author
author2 Kalcioglu,M. Tayyar
Sahin,Nurhan
Bayindir,Tuba
Samdanci,Emine
Filiz,Aliye
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Tan,Mehmet
Kalcioglu,M. Tayyar
Sahin,Nurhan
Bayindir,Tuba
Samdanci,Emine
Filiz,Aliye
dc.subject.por.fl_str_mv Nasal mucosa
Nasal septal perforation
Nasal septum
Tampons surgical
topic Nasal mucosa
Nasal septal perforation
Nasal septum
Tampons surgical
description INTRODUCTION: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation.OBJECTIVES: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model.METHODS: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored.RESULTS: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D.CONCLUSIONS: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000200184
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000200184
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjorl.2014.08.004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
dc.source.none.fl_str_mv Brazilian Journal of Otorhinolaryngology v.81 n.2 2015
reponame:Brazilian Journal of Otorhinolaryngology
instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
instname_str Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron_str ABORL-CCF
institution ABORL-CCF
reponame_str Brazilian Journal of Otorhinolaryngology
collection Brazilian Journal of Otorhinolaryngology
repository.name.fl_str_mv Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
repository.mail.fl_str_mv revista@aborlccf.org.br||revista@aborlccf.org.br
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