Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer

Detalhes bibliográficos
Autor(a) principal: Landolfo,Vincenzo
Data de Publicação: 2018
Outros Autores: Gervasio,Carmine Fernando, Riva,Giuseppe, Garzaro,Massimiliano, Audisio,Rita, Pecorari,Giancarlo, Albera,Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942018000100074
Resumo: Abstract Introduction Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. Objectives The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. Methods Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed. Results Margin status is related to recurrence rate in both groups (p < 0.05) without significant differences between open and laser cordectomy (p > 0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p > 0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p < 0.05). Conclusions Margin status has a prognostic role in T1a-T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.
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spelling Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancerLaryngeal neoplasmsEarly glottic cancerMargin statusOverall survivalDisease free survivalAbstract Introduction Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. Objectives The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. Methods Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed. Results Margin status is related to recurrence rate in both groups (p < 0.05) without significant differences between open and laser cordectomy (p > 0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p > 0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p < 0.05). Conclusions Margin status has a prognostic role in T1a-T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942018000100074Brazilian Journal of Otorhinolaryngology v.84 n.1 2018reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1016/j.bjorl.2016.11.006info:eu-repo/semantics/openAccessLandolfo,VincenzoGervasio,Carmine FernandoRiva,GiuseppeGarzaro,MassimilianoAudisio,RitaPecorari,GiancarloAlbera,Robertoeng2018-02-16T00:00:00Zoai:scielo:S1808-86942018000100074Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2018-02-16T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false
dc.title.none.fl_str_mv Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
title Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
spellingShingle Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
Landolfo,Vincenzo
Laryngeal neoplasms
Early glottic cancer
Margin status
Overall survival
Disease free survival
title_short Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
title_full Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
title_fullStr Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
title_full_unstemmed Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
title_sort Prognostic role of margin status in open and CO2 laser cordectomy for T1a-T1b glottic cancer
author Landolfo,Vincenzo
author_facet Landolfo,Vincenzo
Gervasio,Carmine Fernando
Riva,Giuseppe
Garzaro,Massimiliano
Audisio,Rita
Pecorari,Giancarlo
Albera,Roberto
author_role author
author2 Gervasio,Carmine Fernando
Riva,Giuseppe
Garzaro,Massimiliano
Audisio,Rita
Pecorari,Giancarlo
Albera,Roberto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Landolfo,Vincenzo
Gervasio,Carmine Fernando
Riva,Giuseppe
Garzaro,Massimiliano
Audisio,Rita
Pecorari,Giancarlo
Albera,Roberto
dc.subject.por.fl_str_mv Laryngeal neoplasms
Early glottic cancer
Margin status
Overall survival
Disease free survival
topic Laryngeal neoplasms
Early glottic cancer
Margin status
Overall survival
Disease free survival
description Abstract Introduction Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. Objectives The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. Methods Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed. Results Margin status is related to recurrence rate in both groups (p < 0.05) without significant differences between open and laser cordectomy (p > 0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p > 0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p < 0.05). Conclusions Margin status has a prognostic role in T1a-T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942018000100074
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942018000100074
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjorl.2016.11.006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
dc.source.none.fl_str_mv Brazilian Journal of Otorhinolaryngology v.84 n.1 2018
reponame:Brazilian Journal of Otorhinolaryngology
instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
instname_str Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron_str ABORL-CCF
institution ABORL-CCF
reponame_str Brazilian Journal of Otorhinolaryngology
collection Brazilian Journal of Otorhinolaryngology
repository.name.fl_str_mv Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
repository.mail.fl_str_mv revista@aborlccf.org.br||revista@aborlccf.org.br
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