Noninvasive brain stimulation in psychiatric disorders: a primer
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100070 |
Resumo: | Objective: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. Methods: We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders. Results: We reviewed the mechanisms of action, safety, tolerability, efficacy, and relevant clinical parameters of NIBS. Repetitive TMS is already an established technique for the treatment of depression, and there is theoretically room for further methodological development towards a high-end therapeutic intervention. In contrast, tDCS is a technically easier method and therefore potentially suitable for wider clinical use. However the evidence of its antidepressant efficacy is less sound, and a recent study found tDCS to be inferior to antidepressant pharmacotherapy. Clinical trials using rTMS for other mental disorders produced mixed findings, whereas tDCS use has not been sufficiently appraised. Conclusion: The most promising results of NIBS have been obtained for depression. These techniques excel in safety and tolerability, although their efficacy still warrants improvement. |
id |
ABP-1_37efcfc933e31984be4ffe2d9a91df73 |
---|---|
oai_identifier_str |
oai:scielo:S1516-44462019000100070 |
network_acronym_str |
ABP-1 |
network_name_str |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
repository_id_str |
|
spelling |
Noninvasive brain stimulation in psychiatric disorders: a primerTranscranial magnetic stimulationtranscranial direct current stimulationmental disordersmajor depressive disorderreview Objective: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. Methods: We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders. Results: We reviewed the mechanisms of action, safety, tolerability, efficacy, and relevant clinical parameters of NIBS. Repetitive TMS is already an established technique for the treatment of depression, and there is theoretically room for further methodological development towards a high-end therapeutic intervention. In contrast, tDCS is a technically easier method and therefore potentially suitable for wider clinical use. However the evidence of its antidepressant efficacy is less sound, and a recent study found tDCS to be inferior to antidepressant pharmacotherapy. Clinical trials using rTMS for other mental disorders produced mixed findings, whereas tDCS use has not been sufficiently appraised. Conclusion: The most promising results of NIBS have been obtained for depression. These techniques excel in safety and tolerability, although their efficacy still warrants improvement.Associação Brasileira de Psiquiatria2019-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100070Brazilian Journal of Psychiatry v.41 n.1 2019reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/1516-4446-2017-0018info:eu-repo/semantics/openAccessBrunoni,Andre R.Sampaio-Junior,BernardoMoffa,Adriano H.Aparício,Luana V.Gordon,PedroKlein,IzioRios,Rosa M.Razza,Lais B.Loo,ColleenPadberg,FrankValiengo,Leandroeng2019-10-10T00:00:00Zoai:scielo:S1516-44462019000100070Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2019-10-10T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false |
dc.title.none.fl_str_mv |
Noninvasive brain stimulation in psychiatric disorders: a primer |
title |
Noninvasive brain stimulation in psychiatric disorders: a primer |
spellingShingle |
Noninvasive brain stimulation in psychiatric disorders: a primer Brunoni,Andre R. Transcranial magnetic stimulation transcranial direct current stimulation mental disorders major depressive disorder review |
title_short |
Noninvasive brain stimulation in psychiatric disorders: a primer |
title_full |
Noninvasive brain stimulation in psychiatric disorders: a primer |
title_fullStr |
Noninvasive brain stimulation in psychiatric disorders: a primer |
title_full_unstemmed |
Noninvasive brain stimulation in psychiatric disorders: a primer |
title_sort |
Noninvasive brain stimulation in psychiatric disorders: a primer |
author |
Brunoni,Andre R. |
author_facet |
Brunoni,Andre R. Sampaio-Junior,Bernardo Moffa,Adriano H. Aparício,Luana V. Gordon,Pedro Klein,Izio Rios,Rosa M. Razza,Lais B. Loo,Colleen Padberg,Frank Valiengo,Leandro |
author_role |
author |
author2 |
Sampaio-Junior,Bernardo Moffa,Adriano H. Aparício,Luana V. Gordon,Pedro Klein,Izio Rios,Rosa M. Razza,Lais B. Loo,Colleen Padberg,Frank Valiengo,Leandro |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Brunoni,Andre R. Sampaio-Junior,Bernardo Moffa,Adriano H. Aparício,Luana V. Gordon,Pedro Klein,Izio Rios,Rosa M. Razza,Lais B. Loo,Colleen Padberg,Frank Valiengo,Leandro |
dc.subject.por.fl_str_mv |
Transcranial magnetic stimulation transcranial direct current stimulation mental disorders major depressive disorder review |
topic |
Transcranial magnetic stimulation transcranial direct current stimulation mental disorders major depressive disorder review |
description |
Objective: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. Methods: We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders. Results: We reviewed the mechanisms of action, safety, tolerability, efficacy, and relevant clinical parameters of NIBS. Repetitive TMS is already an established technique for the treatment of depression, and there is theoretically room for further methodological development towards a high-end therapeutic intervention. In contrast, tDCS is a technically easier method and therefore potentially suitable for wider clinical use. However the evidence of its antidepressant efficacy is less sound, and a recent study found tDCS to be inferior to antidepressant pharmacotherapy. Clinical trials using rTMS for other mental disorders produced mixed findings, whereas tDCS use has not been sufficiently appraised. Conclusion: The most promising results of NIBS have been obtained for depression. These techniques excel in safety and tolerability, although their efficacy still warrants improvement. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100070 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100070 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1516-4446-2017-0018 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Psiquiatria |
publisher.none.fl_str_mv |
Associação Brasileira de Psiquiatria |
dc.source.none.fl_str_mv |
Brazilian Journal of Psychiatry v.41 n.1 2019 reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online) instname:Associação Brasileira de Psiquiatria (ABP) instacron:ABP |
instname_str |
Associação Brasileira de Psiquiatria (ABP) |
instacron_str |
ABP |
institution |
ABP |
reponame_str |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
collection |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
repository.name.fl_str_mv |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP) |
repository.mail.fl_str_mv |
||rbp@abpbrasil.org.br |
_version_ |
1754212558609317888 |