Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America

Detalhes bibliográficos
Autor(a) principal: Carta,Mauro G.
Data de Publicação: 2020
Outros Autores: Moro,Maria F., Piras,Martina, Ledda,Vanessa, Prina,Eleonora, Stocchino,Serena, Orrù,Germano, Romano,Ferdinando, Brasesco,Maria V., Freire,Rafael C., Nardi,Antonio E., Tondo,Leonardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462020000100012
Resumo: Objective: To determine whether people with a Sardinian genetic background who live in the megacities of South America have a higher frequency of hypomania than residents of Sardinia. Methods: A community survey of Sardinian immigrants was carried out in four Brazilian metropoles (n=218) and Buenos Aires (n=306). The results were compared with those of a study involving a similar methodology (Mood Disorder Questionnaire [MDQ] as a screening tool) conducted in seven Italian regions, including a sub-sample from Sardinia. Results: There was a higher prevalence of lifetime hypomania among Sardinians living in the Brazilian metropoles than among those living in Sardinia. This result was also consistent with Sardinian immigrants in Buenos Aires. After stratification by sex and age, the lifetime prevalence of MDQ scores ≥ 8 among Sardinians in South-American megacities and Sardinia was 8.6% vs. 2.9%, respectively (p < 0.0001). Conclusions: The higher frequency of hypomania in migrant populations appears to favor an evolutionary view in which mood disorders may be a maladaptive aspect of a genetic background with adaptive characteristics.
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spelling Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin AmericaBipolar disordermigrationevolutionary approachmegacitiesLatin America Objective: To determine whether people with a Sardinian genetic background who live in the megacities of South America have a higher frequency of hypomania than residents of Sardinia. Methods: A community survey of Sardinian immigrants was carried out in four Brazilian metropoles (n=218) and Buenos Aires (n=306). The results were compared with those of a study involving a similar methodology (Mood Disorder Questionnaire [MDQ] as a screening tool) conducted in seven Italian regions, including a sub-sample from Sardinia. Results: There was a higher prevalence of lifetime hypomania among Sardinians living in the Brazilian metropoles than among those living in Sardinia. This result was also consistent with Sardinian immigrants in Buenos Aires. After stratification by sex and age, the lifetime prevalence of MDQ scores ≥ 8 among Sardinians in South-American megacities and Sardinia was 8.6% vs. 2.9%, respectively (p < 0.0001). Conclusions: The higher frequency of hypomania in migrant populations appears to favor an evolutionary view in which mood disorders may be a maladaptive aspect of a genetic background with adaptive characteristics.Associação Brasileira de Psiquiatria2020-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462020000100012Brazilian Journal of Psychiatry v.42 n.1 2020reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/1516-4446-2018-0338info:eu-repo/semantics/openAccessCarta,Mauro G.Moro,Maria F.Piras,MartinaLedda,VanessaPrina,EleonoraStocchino,SerenaOrrù,GermanoRomano,FerdinandoBrasesco,Maria V.Freire,Rafael C.Nardi,Antonio E.Tondo,Leonardoeng2020-04-01T00:00:00Zoai:scielo:S1516-44462020000100012Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2020-04-01T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
title Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
spellingShingle Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
Carta,Mauro G.
Bipolar disorder
migration
evolutionary approach
megacities
Latin America
title_short Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
title_full Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
title_fullStr Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
title_full_unstemmed Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
title_sort Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
author Carta,Mauro G.
author_facet Carta,Mauro G.
Moro,Maria F.
Piras,Martina
Ledda,Vanessa
Prina,Eleonora
Stocchino,Serena
Orrù,Germano
Romano,Ferdinando
Brasesco,Maria V.
Freire,Rafael C.
Nardi,Antonio E.
Tondo,Leonardo
author_role author
author2 Moro,Maria F.
Piras,Martina
Ledda,Vanessa
Prina,Eleonora
Stocchino,Serena
Orrù,Germano
Romano,Ferdinando
Brasesco,Maria V.
Freire,Rafael C.
Nardi,Antonio E.
Tondo,Leonardo
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carta,Mauro G.
Moro,Maria F.
Piras,Martina
Ledda,Vanessa
Prina,Eleonora
Stocchino,Serena
Orrù,Germano
Romano,Ferdinando
Brasesco,Maria V.
Freire,Rafael C.
Nardi,Antonio E.
Tondo,Leonardo
dc.subject.por.fl_str_mv Bipolar disorder
migration
evolutionary approach
megacities
Latin America
topic Bipolar disorder
migration
evolutionary approach
megacities
Latin America
description Objective: To determine whether people with a Sardinian genetic background who live in the megacities of South America have a higher frequency of hypomania than residents of Sardinia. Methods: A community survey of Sardinian immigrants was carried out in four Brazilian metropoles (n=218) and Buenos Aires (n=306). The results were compared with those of a study involving a similar methodology (Mood Disorder Questionnaire [MDQ] as a screening tool) conducted in seven Italian regions, including a sub-sample from Sardinia. Results: There was a higher prevalence of lifetime hypomania among Sardinians living in the Brazilian metropoles than among those living in Sardinia. This result was also consistent with Sardinian immigrants in Buenos Aires. After stratification by sex and age, the lifetime prevalence of MDQ scores ≥ 8 among Sardinians in South-American megacities and Sardinia was 8.6% vs. 2.9%, respectively (p < 0.0001). Conclusions: The higher frequency of hypomania in migrant populations appears to favor an evolutionary view in which mood disorders may be a maladaptive aspect of a genetic background with adaptive characteristics.
publishDate 2020
dc.date.none.fl_str_mv 2020-02-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1516-4446-2018-0338
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dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Brazilian Journal of Psychiatry v.42 n.1 2020
reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
instname:Associação Brasileira de Psiquiatria (ABP)
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instname_str Associação Brasileira de Psiquiatria (ABP)
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reponame_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
collection Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository.name.fl_str_mv Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)
repository.mail.fl_str_mv ||rbp@abpbrasil.org.br
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