Determinants of adherence to treatment in first-episode psychosis: a comprehensive review

Detalhes bibliográficos
Autor(a) principal: Leclerc,Emilie
Data de Publicação: 2015
Outros Autores: Noto,Cristiano, Bressan,Rodrigo A., Brietzke,Elisa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462015000200168
Resumo: Objective:To conduct a comprehensive review of current evidence on factors for nonadherence to treatment in individuals with first-episode psychosis (FEP).Methods:MEDLINE, LILACS, PsycINFO, and SciELO databases were searched with the keywords first episode psychosis, factor, adherence, nonadherence, engagement, disengagement, compliance, and intervention. References of selected studies were consulted for relevant articles.Results:A total of 157 articles were screened, of which 33 articles were retained for full review. The factors related to nonadherence were: a) patient-related (e.g., lower education level, persistent substance use, forensic history, unemployment, history of physical abuse); b) environment-related (e.g., no family involved in treatment, social adjustment difficulties); c) medication-related (e.g., rapid remission of negative symptoms when starting treatment, therapeutic alliance); and d) illness-related (e.g., more positive symptoms, more relapses). Treatment factors that improve adherence include a good therapeutic alliance and a voluntary first admission when hospitalization occurs.Conclusion:The results of this review suggest that nonadherence to treatment in FEP is multifactorial. Many of these factors are modifiable and can be specifically targeted in early intervention programs. Very few studies have assessed strategies to raise adherence in FEP.
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spelling Determinants of adherence to treatment in first-episode psychosis: a comprehensive reviewMedication adherencepatient dropoutsrisk factorsschizophreniabipolar disorderObjective:To conduct a comprehensive review of current evidence on factors for nonadherence to treatment in individuals with first-episode psychosis (FEP).Methods:MEDLINE, LILACS, PsycINFO, and SciELO databases were searched with the keywords first episode psychosis, factor, adherence, nonadherence, engagement, disengagement, compliance, and intervention. References of selected studies were consulted for relevant articles.Results:A total of 157 articles were screened, of which 33 articles were retained for full review. The factors related to nonadherence were: a) patient-related (e.g., lower education level, persistent substance use, forensic history, unemployment, history of physical abuse); b) environment-related (e.g., no family involved in treatment, social adjustment difficulties); c) medication-related (e.g., rapid remission of negative symptoms when starting treatment, therapeutic alliance); and d) illness-related (e.g., more positive symptoms, more relapses). Treatment factors that improve adherence include a good therapeutic alliance and a voluntary first admission when hospitalization occurs.Conclusion:The results of this review suggest that nonadherence to treatment in FEP is multifactorial. Many of these factors are modifiable and can be specifically targeted in early intervention programs. Very few studies have assessed strategies to raise adherence in FEP.Associação Brasileira de Psiquiatria2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462015000200168Brazilian Journal of Psychiatry v.37 n.2 2015reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/1516-4446-2014-1539info:eu-repo/semantics/openAccessLeclerc,EmilieNoto,CristianoBressan,Rodrigo A.Brietzke,Elisaeng2015-09-10T00:00:00Zoai:scielo:S1516-44462015000200168Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2015-09-10T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
title Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
spellingShingle Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
Leclerc,Emilie
Medication adherence
patient dropouts
risk factors
schizophrenia
bipolar disorder
title_short Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
title_full Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
title_fullStr Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
title_full_unstemmed Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
title_sort Determinants of adherence to treatment in first-episode psychosis: a comprehensive review
author Leclerc,Emilie
author_facet Leclerc,Emilie
Noto,Cristiano
Bressan,Rodrigo A.
Brietzke,Elisa
author_role author
author2 Noto,Cristiano
Bressan,Rodrigo A.
Brietzke,Elisa
author2_role author
author
author
dc.contributor.author.fl_str_mv Leclerc,Emilie
Noto,Cristiano
Bressan,Rodrigo A.
Brietzke,Elisa
dc.subject.por.fl_str_mv Medication adherence
patient dropouts
risk factors
schizophrenia
bipolar disorder
topic Medication adherence
patient dropouts
risk factors
schizophrenia
bipolar disorder
description Objective:To conduct a comprehensive review of current evidence on factors for nonadherence to treatment in individuals with first-episode psychosis (FEP).Methods:MEDLINE, LILACS, PsycINFO, and SciELO databases were searched with the keywords first episode psychosis, factor, adherence, nonadherence, engagement, disengagement, compliance, and intervention. References of selected studies were consulted for relevant articles.Results:A total of 157 articles were screened, of which 33 articles were retained for full review. The factors related to nonadherence were: a) patient-related (e.g., lower education level, persistent substance use, forensic history, unemployment, history of physical abuse); b) environment-related (e.g., no family involved in treatment, social adjustment difficulties); c) medication-related (e.g., rapid remission of negative symptoms when starting treatment, therapeutic alliance); and d) illness-related (e.g., more positive symptoms, more relapses). Treatment factors that improve adherence include a good therapeutic alliance and a voluntary first admission when hospitalization occurs.Conclusion:The results of this review suggest that nonadherence to treatment in FEP is multifactorial. Many of these factors are modifiable and can be specifically targeted in early intervention programs. Very few studies have assessed strategies to raise adherence in FEP.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1516-4446-2014-1539
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dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Brazilian Journal of Psychiatry v.37 n.2 2015
reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
instname:Associação Brasileira de Psiquiatria (ABP)
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instname_str Associação Brasileira de Psiquiatria (ABP)
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reponame_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
collection Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository.name.fl_str_mv Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)
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