Risk factors for eating disorders: an umbrella review of published meta-analyses

Detalhes bibliográficos
Autor(a) principal: Solmi,Marco
Data de Publicação: 2021
Outros Autores: Radua,Joaquim, Stubbs,Brendon, Ricca,Valdo, Moretti,Davide, Busatta,Daniele, Carvalho,Andre F., Dragioti,Elena, Favaro,Angela, Monteleone,Alessio Maria, Shin,Jae Il, Fusar-Poli,Paolo, Castellini,Giovanni
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462021000300314
Resumo: Objective: To grade the evidence about risk factors for eating disorders (anorexia nervosa, bulimia nervosa, and binge eating disorder) with an umbrella review approach. Methods: This was a systematic review of observational studies on risk factors for eating disorders published in PubMed/PsycInfo/Embase until December 11th, 2019. We recalculated random-effect meta-analyses, heterogeneity, small-study effect, excess significance bias and 95% prediction intervals, grading significant evidence (p < 0.05) from convincing to weak according to established criteria. Quality was assessed with the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2) tool. Results: Of 2,197 meta-analyses, nine were included, providing evidence on 50 risk factors, 29,272 subjects with eating disorders, and 1,679,385 controls. Although no association was supported by convincing evidence, highly suggestive evidence supported the association between childhood sexual abuse and bulimia nervosa (k = 29, 1,103 cases with eating disorders, 8,496 controls, OR, 2.73, 95%CI 1.96-3.79, p = 2.1 x 10-9, AMSTAR-2 moderate quality) and between appearance-related teasing victimization and any eating disorder (k = 10, 1,341 cases with eating disorders, 3,295 controls, OR 2.91, 95%CI 2.05-4.12, p = 1.8x10-9, AMSTAR-2 moderate quality). Suggestive, weak, or no evidence supported 11, 29, and 8 associations, respectively. Conclusions: The most credible evidence indicates that early traumatic and stressful events are risk factors for eating disorders. Larger collaborative prospective cohort studies are needed to identify risk factors for eating disorders, particularly anorexia nervosa.
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spelling Risk factors for eating disorders: an umbrella review of published meta-analysesEating disordersanorexia nervosabulimia nervosabinge eating disorder: umbrella reviewsystematic reviewmeta-analysisrisk factorprevention Objective: To grade the evidence about risk factors for eating disorders (anorexia nervosa, bulimia nervosa, and binge eating disorder) with an umbrella review approach. Methods: This was a systematic review of observational studies on risk factors for eating disorders published in PubMed/PsycInfo/Embase until December 11th, 2019. We recalculated random-effect meta-analyses, heterogeneity, small-study effect, excess significance bias and 95% prediction intervals, grading significant evidence (p < 0.05) from convincing to weak according to established criteria. Quality was assessed with the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2) tool. Results: Of 2,197 meta-analyses, nine were included, providing evidence on 50 risk factors, 29,272 subjects with eating disorders, and 1,679,385 controls. Although no association was supported by convincing evidence, highly suggestive evidence supported the association between childhood sexual abuse and bulimia nervosa (k = 29, 1,103 cases with eating disorders, 8,496 controls, OR, 2.73, 95%CI 1.96-3.79, p = 2.1 x 10-9, AMSTAR-2 moderate quality) and between appearance-related teasing victimization and any eating disorder (k = 10, 1,341 cases with eating disorders, 3,295 controls, OR 2.91, 95%CI 2.05-4.12, p = 1.8x10-9, AMSTAR-2 moderate quality). Suggestive, weak, or no evidence supported 11, 29, and 8 associations, respectively. Conclusions: The most credible evidence indicates that early traumatic and stressful events are risk factors for eating disorders. Larger collaborative prospective cohort studies are needed to identify risk factors for eating disorders, particularly anorexia nervosa.Associação Brasileira de Psiquiatria2021-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462021000300314Brazilian Journal of Psychiatry v.43 n.3 2021reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/1516-4446-2020-1099info:eu-repo/semantics/openAccessSolmi,MarcoRadua,JoaquimStubbs,BrendonRicca,ValdoMoretti,DavideBusatta,DanieleCarvalho,Andre F.Dragioti,ElenaFavaro,AngelaMonteleone,Alessio MariaShin,Jae IlFusar-Poli,PaoloCastellini,Giovannieng2021-05-28T00:00:00Zoai:scielo:S1516-44462021000300314Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2021-05-28T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv Risk factors for eating disorders: an umbrella review of published meta-analyses
title Risk factors for eating disorders: an umbrella review of published meta-analyses
spellingShingle Risk factors for eating disorders: an umbrella review of published meta-analyses
Solmi,Marco
Eating disorders
anorexia nervosa
bulimia nervosa
binge eating disorder: umbrella review
systematic review
meta-analysis
risk factor
prevention
title_short Risk factors for eating disorders: an umbrella review of published meta-analyses
title_full Risk factors for eating disorders: an umbrella review of published meta-analyses
title_fullStr Risk factors for eating disorders: an umbrella review of published meta-analyses
title_full_unstemmed Risk factors for eating disorders: an umbrella review of published meta-analyses
title_sort Risk factors for eating disorders: an umbrella review of published meta-analyses
author Solmi,Marco
author_facet Solmi,Marco
Radua,Joaquim
Stubbs,Brendon
Ricca,Valdo
Moretti,Davide
Busatta,Daniele
Carvalho,Andre F.
Dragioti,Elena
Favaro,Angela
Monteleone,Alessio Maria
Shin,Jae Il
Fusar-Poli,Paolo
Castellini,Giovanni
author_role author
author2 Radua,Joaquim
Stubbs,Brendon
Ricca,Valdo
Moretti,Davide
Busatta,Daniele
Carvalho,Andre F.
Dragioti,Elena
Favaro,Angela
Monteleone,Alessio Maria
Shin,Jae Il
Fusar-Poli,Paolo
Castellini,Giovanni
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Solmi,Marco
Radua,Joaquim
Stubbs,Brendon
Ricca,Valdo
Moretti,Davide
Busatta,Daniele
Carvalho,Andre F.
Dragioti,Elena
Favaro,Angela
Monteleone,Alessio Maria
Shin,Jae Il
Fusar-Poli,Paolo
Castellini,Giovanni
dc.subject.por.fl_str_mv Eating disorders
anorexia nervosa
bulimia nervosa
binge eating disorder: umbrella review
systematic review
meta-analysis
risk factor
prevention
topic Eating disorders
anorexia nervosa
bulimia nervosa
binge eating disorder: umbrella review
systematic review
meta-analysis
risk factor
prevention
description Objective: To grade the evidence about risk factors for eating disorders (anorexia nervosa, bulimia nervosa, and binge eating disorder) with an umbrella review approach. Methods: This was a systematic review of observational studies on risk factors for eating disorders published in PubMed/PsycInfo/Embase until December 11th, 2019. We recalculated random-effect meta-analyses, heterogeneity, small-study effect, excess significance bias and 95% prediction intervals, grading significant evidence (p < 0.05) from convincing to weak according to established criteria. Quality was assessed with the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2) tool. Results: Of 2,197 meta-analyses, nine were included, providing evidence on 50 risk factors, 29,272 subjects with eating disorders, and 1,679,385 controls. Although no association was supported by convincing evidence, highly suggestive evidence supported the association between childhood sexual abuse and bulimia nervosa (k = 29, 1,103 cases with eating disorders, 8,496 controls, OR, 2.73, 95%CI 1.96-3.79, p = 2.1 x 10-9, AMSTAR-2 moderate quality) and between appearance-related teasing victimization and any eating disorder (k = 10, 1,341 cases with eating disorders, 3,295 controls, OR 2.91, 95%CI 2.05-4.12, p = 1.8x10-9, AMSTAR-2 moderate quality). Suggestive, weak, or no evidence supported 11, 29, and 8 associations, respectively. Conclusions: The most credible evidence indicates that early traumatic and stressful events are risk factors for eating disorders. Larger collaborative prospective cohort studies are needed to identify risk factors for eating disorders, particularly anorexia nervosa.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462021000300314
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462021000300314
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1516-4446-2020-1099
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Brazilian Journal of Psychiatry v.43 n.3 2021
reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
instname:Associação Brasileira de Psiquiatria (ABP)
instacron:ABP
instname_str Associação Brasileira de Psiquiatria (ABP)
instacron_str ABP
institution ABP
reponame_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
collection Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository.name.fl_str_mv Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)
repository.mail.fl_str_mv ||rbp@abpbrasil.org.br
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