Subclinical hypothyroidism: psychiatric disorders and symptoms
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462007000200013 |
Resumo: | OBJECTIVE: To evaluate the prevalence of psychiatric disorders and symptoms in patients with subclinical hypothyroidism. METHOD: Ninety-four outpatients with at least two elevated serum thyrotrophin levels (> 4 µU/ml) and normal FT4, and 43 euthyroid outpatients, both groups from HUCFF-UFRJ, were evaluated. Psychiatric diagnosis was based on the Structured Clinical Interview Diagnostic for the DSM-IV axis I (SCID-I/DSM-IV), the psychopathological symptoms on Hamilton anxiety and depression scales, and the Beck Inventory. RESULTS: Our data showed an increased prevalence of psychiatric disorders in the subclinical hypothyroidism patients when compared to the euthyroid group (45.7% vs 25.6%; p = 0.025), mood disorders being the most frequent. The prevalence of depressive symptoms based on Beck's Scale among subclinical hypothyroidism patients was about 2.3 times higher than among euthyroid ones (45.6% vs 20.9%, p = 0.006). Anxiety symptoms were also more frequent among subclinical hypothyroidism patients (87.0% vs 60.5%, p < 0.001), mainly clinical anxiety (44.6% vs 23.3%; p = 0.001). CONCLUSION: Our results showed a significant association of subclinical hypothyroidism with psychiatric disorders and an increased frequency of subsyndromic depression and anxiety symptoms in subclinical hypothyroidism in relation to the euthyroid group. |
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Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
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Subclinical hypothyroidism: psychiatric disorders and symptomsHypothyroidismAnxiety disordersMood disordersSymptomsPrevalenceOBJECTIVE: To evaluate the prevalence of psychiatric disorders and symptoms in patients with subclinical hypothyroidism. METHOD: Ninety-four outpatients with at least two elevated serum thyrotrophin levels (> 4 µU/ml) and normal FT4, and 43 euthyroid outpatients, both groups from HUCFF-UFRJ, were evaluated. Psychiatric diagnosis was based on the Structured Clinical Interview Diagnostic for the DSM-IV axis I (SCID-I/DSM-IV), the psychopathological symptoms on Hamilton anxiety and depression scales, and the Beck Inventory. RESULTS: Our data showed an increased prevalence of psychiatric disorders in the subclinical hypothyroidism patients when compared to the euthyroid group (45.7% vs 25.6%; p = 0.025), mood disorders being the most frequent. The prevalence of depressive symptoms based on Beck's Scale among subclinical hypothyroidism patients was about 2.3 times higher than among euthyroid ones (45.6% vs 20.9%, p = 0.006). Anxiety symptoms were also more frequent among subclinical hypothyroidism patients (87.0% vs 60.5%, p < 0.001), mainly clinical anxiety (44.6% vs 23.3%; p = 0.001). CONCLUSION: Our results showed a significant association of subclinical hypothyroidism with psychiatric disorders and an increased frequency of subsyndromic depression and anxiety symptoms in subclinical hypothyroidism in relation to the euthyroid group.Associação Brasileira de Psiquiatria2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462007000200013Brazilian Journal of Psychiatry v.29 n.2 2007reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/S1516-44462007000200013info:eu-repo/semantics/openAccessAlmeida,CloyraBrasil,Marco AntônioCosta,Antônio José LealReis,Fabiola A AReuters,VaneskaTeixeira,PatríciaFerreira,MárciaMarques,Amanda MMelo,Bianca ATeixeira,Letícia B B de MBuescu,AlexandreVaisman,Márioeng2007-07-06T00:00:00Zoai:scielo:S1516-44462007000200013Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2007-07-06T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false |
dc.title.none.fl_str_mv |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
title |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
spellingShingle |
Subclinical hypothyroidism: psychiatric disorders and symptoms Almeida,Cloyra Hypothyroidism Anxiety disorders Mood disorders Symptoms Prevalence |
title_short |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
title_full |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
title_fullStr |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
title_full_unstemmed |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
title_sort |
Subclinical hypothyroidism: psychiatric disorders and symptoms |
author |
Almeida,Cloyra |
author_facet |
Almeida,Cloyra Brasil,Marco Antônio Costa,Antônio José Leal Reis,Fabiola A A Reuters,Vaneska Teixeira,Patrícia Ferreira,Márcia Marques,Amanda M Melo,Bianca A Teixeira,Letícia B B de M Buescu,Alexandre Vaisman,Mário |
author_role |
author |
author2 |
Brasil,Marco Antônio Costa,Antônio José Leal Reis,Fabiola A A Reuters,Vaneska Teixeira,Patrícia Ferreira,Márcia Marques,Amanda M Melo,Bianca A Teixeira,Letícia B B de M Buescu,Alexandre Vaisman,Mário |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Almeida,Cloyra Brasil,Marco Antônio Costa,Antônio José Leal Reis,Fabiola A A Reuters,Vaneska Teixeira,Patrícia Ferreira,Márcia Marques,Amanda M Melo,Bianca A Teixeira,Letícia B B de M Buescu,Alexandre Vaisman,Mário |
dc.subject.por.fl_str_mv |
Hypothyroidism Anxiety disorders Mood disorders Symptoms Prevalence |
topic |
Hypothyroidism Anxiety disorders Mood disorders Symptoms Prevalence |
description |
OBJECTIVE: To evaluate the prevalence of psychiatric disorders and symptoms in patients with subclinical hypothyroidism. METHOD: Ninety-four outpatients with at least two elevated serum thyrotrophin levels (> 4 µU/ml) and normal FT4, and 43 euthyroid outpatients, both groups from HUCFF-UFRJ, were evaluated. Psychiatric diagnosis was based on the Structured Clinical Interview Diagnostic for the DSM-IV axis I (SCID-I/DSM-IV), the psychopathological symptoms on Hamilton anxiety and depression scales, and the Beck Inventory. RESULTS: Our data showed an increased prevalence of psychiatric disorders in the subclinical hypothyroidism patients when compared to the euthyroid group (45.7% vs 25.6%; p = 0.025), mood disorders being the most frequent. The prevalence of depressive symptoms based on Beck's Scale among subclinical hypothyroidism patients was about 2.3 times higher than among euthyroid ones (45.6% vs 20.9%, p = 0.006). Anxiety symptoms were also more frequent among subclinical hypothyroidism patients (87.0% vs 60.5%, p < 0.001), mainly clinical anxiety (44.6% vs 23.3%; p = 0.001). CONCLUSION: Our results showed a significant association of subclinical hypothyroidism with psychiatric disorders and an increased frequency of subsyndromic depression and anxiety symptoms in subclinical hypothyroidism in relation to the euthyroid group. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462007000200013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462007000200013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-44462007000200013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Psiquiatria |
publisher.none.fl_str_mv |
Associação Brasileira de Psiquiatria |
dc.source.none.fl_str_mv |
Brazilian Journal of Psychiatry v.29 n.2 2007 reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online) instname:Associação Brasileira de Psiquiatria (ABP) instacron:ABP |
instname_str |
Associação Brasileira de Psiquiatria (ABP) |
instacron_str |
ABP |
institution |
ABP |
reponame_str |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
collection |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) |
repository.name.fl_str_mv |
Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP) |
repository.mail.fl_str_mv |
||rbp@abpbrasil.org.br |
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1754212553781673984 |