Melatonin agonists in the treatment of insomnia and depression

Detalhes bibliográficos
Autor(a) principal: Krieger, Débora Mascella
Data de Publicação: 2014
Outros Autores: Barros, Carlos Alberto Sampaio Martins de, Mello, Elisa Fasolin, Terra, Mauro Barbosa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Debates em Psiquiatria (Online)
Texto Completo: https://revistardp.org.br/revista/article/view/197
Resumo: Insomnia and depression are very common conditions of morbidity and mortality in general population. The concurrence of both conditions simultaneously in the same patient is very often. There are several available agents for their treatments, but side effects and poor response are the reasons for abandoning therapy. The understanding of the physiology of daytime rhythm over sleep and humor has led to the study of melatonin and its analogs. They propose the treatment of both conditions with a different mechanism of action from the present options for clinical use. The role of melatonin and its analogs is the objective of this review.
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spelling Melatonin agonists in the treatment of insomnia and depressionAgonistas da melatonina no tratamento da insônia e da depressãoMelatoninaInsôniaDepressão maiorMelatoninInsomniaMajor Depressive DisorderInsomnia and depression are very common conditions of morbidity and mortality in general population. The concurrence of both conditions simultaneously in the same patient is very often. There are several available agents for their treatments, but side effects and poor response are the reasons for abandoning therapy. The understanding of the physiology of daytime rhythm over sleep and humor has led to the study of melatonin and its analogs. They propose the treatment of both conditions with a different mechanism of action from the present options for clinical use. The role of melatonin and its analogs is the objective of this review.A insônia e a depressão são comuns na população em geral, sendo causas frequentes de morbimortalidade, e a ocorrência das duas afecções no mesmo paciente é muito encontrada. Vários agentes farmacológicos existem no mercado para tratamento de ambas as condições, mas seus parefeitos são motivos de abandono do mesmo. O entendimento do ritmo circadiano bem como do seu impacto sobre o sono e o humor levaram ao estudo da melatonina e de seus derivados. Tem sido proposto o tratamento de ambas as condições com um mecanismo de ação diferente das opções psicofarmacológicas presentes no mercado até o momento. O papel da melatonina e de seus análogos é o objetivo desta revisão.Associação Brasileira de Psiquiatria2014-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-ReviewedRevisado por ParesAvaliado Pelos Paresapplication/pdfhttps://revistardp.org.br/revista/article/view/19710.25118/2236-918X-4-3-2Debates in Psychiatry; Vol. 4 No. 3 (2014); 12-17Debates em Psiquiatria; Vol. 4 Núm. 3 (2014); 12-17Debates em Psiquiatria; v. 4 n. 3 (2014); 12-172763-90372236-918Xreponame:Debates em Psiquiatria (Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABPporhttps://revistardp.org.br/revista/article/view/197/173https://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessKrieger, Débora MascellaBarros, Carlos Alberto Sampaio Martins deMello, Elisa FasolinTerra, Mauro Barbosa2023-06-28T14:56:28Zoai:ojs.emnuvens.com.br:article/197Revistahttps://revistardp.org.br/revista/oaiPUBhttps://revistardp.org.br/revista/oairdp@abp.org.br2763-90372236-918Xopendoar:2023-06-28T14:56:28Debates em Psiquiatria (Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv Melatonin agonists in the treatment of insomnia and depression
Agonistas da melatonina no tratamento da insônia e da depressão
title Melatonin agonists in the treatment of insomnia and depression
spellingShingle Melatonin agonists in the treatment of insomnia and depression
Krieger, Débora Mascella
Melatonina
Insônia
Depressão maior
Melatonin
Insomnia
Major Depressive Disorder
title_short Melatonin agonists in the treatment of insomnia and depression
title_full Melatonin agonists in the treatment of insomnia and depression
title_fullStr Melatonin agonists in the treatment of insomnia and depression
title_full_unstemmed Melatonin agonists in the treatment of insomnia and depression
title_sort Melatonin agonists in the treatment of insomnia and depression
author Krieger, Débora Mascella
author_facet Krieger, Débora Mascella
Barros, Carlos Alberto Sampaio Martins de
Mello, Elisa Fasolin
Terra, Mauro Barbosa
author_role author
author2 Barros, Carlos Alberto Sampaio Martins de
Mello, Elisa Fasolin
Terra, Mauro Barbosa
author2_role author
author
author
dc.contributor.author.fl_str_mv Krieger, Débora Mascella
Barros, Carlos Alberto Sampaio Martins de
Mello, Elisa Fasolin
Terra, Mauro Barbosa
dc.subject.por.fl_str_mv Melatonina
Insônia
Depressão maior
Melatonin
Insomnia
Major Depressive Disorder
topic Melatonina
Insônia
Depressão maior
Melatonin
Insomnia
Major Depressive Disorder
description Insomnia and depression are very common conditions of morbidity and mortality in general population. The concurrence of both conditions simultaneously in the same patient is very often. There are several available agents for their treatments, but side effects and poor response are the reasons for abandoning therapy. The understanding of the physiology of daytime rhythm over sleep and humor has led to the study of melatonin and its analogs. They propose the treatment of both conditions with a different mechanism of action from the present options for clinical use. The role of melatonin and its analogs is the objective of this review.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-Reviewed
Revisado por Pares
Avaliado Pelos Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistardp.org.br/revista/article/view/197
10.25118/2236-918X-4-3-2
url https://revistardp.org.br/revista/article/view/197
identifier_str_mv 10.25118/2236-918X-4-3-2
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistardp.org.br/revista/article/view/197/173
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Debates in Psychiatry; Vol. 4 No. 3 (2014); 12-17
Debates em Psiquiatria; Vol. 4 Núm. 3 (2014); 12-17
Debates em Psiquiatria; v. 4 n. 3 (2014); 12-17
2763-9037
2236-918X
reponame:Debates em Psiquiatria (Online)
instname:Associação Brasileira de Psiquiatria (ABP)
instacron:ABP
instname_str Associação Brasileira de Psiquiatria (ABP)
instacron_str ABP
institution ABP
reponame_str Debates em Psiquiatria (Online)
collection Debates em Psiquiatria (Online)
repository.name.fl_str_mv Debates em Psiquiatria (Online) - Associação Brasileira de Psiquiatria (ABP)
repository.mail.fl_str_mv rdp@abp.org.br
_version_ 1796798364825681920

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