PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity

Detalhes bibliográficos
Autor(a) principal: Hernández,Mónica L.
Data de Publicação: 2012
Outros Autores: Ruiz,Jesús E. G., Ramos,Adrián P., Estévez,Gastón F., Sánchez,Carlos A. T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Polímeros (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282012000400014
Resumo: Bone cements of poly (methyl methacrylate) (PMMA) have been used for about 40 years to fix artificial prosthesis to bone structure. The aim of this study was to evaluate the absorption, solubility, degradation and bioactivity of novel formulations of PMMA/Ca2+ bone cements. These properties were evaluated using a fractional experimental design. Hydrolytic parameters were determined, from which we found that 7/8 of the formulations for absorption and 6/8 for solubility fulfill the ISO 4049:2000 requirements. The final degradation values ranged between 1 and 5%, except for one of the formulations. Besides, some formulations showed bioactivity after seven days of immersion in SBF solution.
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spelling PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivityPMMA cementshydroxyapatitecalcium carbonateBone cements of poly (methyl methacrylate) (PMMA) have been used for about 40 years to fix artificial prosthesis to bone structure. The aim of this study was to evaluate the absorption, solubility, degradation and bioactivity of novel formulations of PMMA/Ca2+ bone cements. These properties were evaluated using a fractional experimental design. Hydrolytic parameters were determined, from which we found that 7/8 of the formulations for absorption and 6/8 for solubility fulfill the ISO 4049:2000 requirements. The final degradation values ranged between 1 and 5%, except for one of the formulations. Besides, some formulations showed bioactivity after seven days of immersion in SBF solution.Associação Brasileira de Polímeros2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282012000400014Polímeros v.22 n.4 2012reponame:Polímeros (São Carlos. Online)instname:Associação Brasileira de Polímeros (ABPol)instacron:ABPO10.1590/S0104-14282012005000067info:eu-repo/semantics/openAccessHernández,Mónica L.Ruiz,Jesús E. G.Ramos,Adrián P.Estévez,Gastón F.Sánchez,Carlos A. T.eng2012-11-27T00:00:00Zoai:scielo:S0104-14282012000400014Revistahttp://www.scielo.br/pohttps://old.scielo.br/oai/scielo-oai.php||revista@abpol.org.br1678-51690104-1428opendoar:2012-11-27T00:00Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)false
dc.title.none.fl_str_mv PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
title PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
spellingShingle PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
Hernández,Mónica L.
PMMA cements
hydroxyapatite
calcium carbonate
title_short PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
title_full PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
title_fullStr PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
title_full_unstemmed PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
title_sort PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
author Hernández,Mónica L.
author_facet Hernández,Mónica L.
Ruiz,Jesús E. G.
Ramos,Adrián P.
Estévez,Gastón F.
Sánchez,Carlos A. T.
author_role author
author2 Ruiz,Jesús E. G.
Ramos,Adrián P.
Estévez,Gastón F.
Sánchez,Carlos A. T.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Hernández,Mónica L.
Ruiz,Jesús E. G.
Ramos,Adrián P.
Estévez,Gastón F.
Sánchez,Carlos A. T.
dc.subject.por.fl_str_mv PMMA cements
hydroxyapatite
calcium carbonate
topic PMMA cements
hydroxyapatite
calcium carbonate
description Bone cements of poly (methyl methacrylate) (PMMA) have been used for about 40 years to fix artificial prosthesis to bone structure. The aim of this study was to evaluate the absorption, solubility, degradation and bioactivity of novel formulations of PMMA/Ca2+ bone cements. These properties were evaluated using a fractional experimental design. Hydrolytic parameters were determined, from which we found that 7/8 of the formulations for absorption and 6/8 for solubility fulfill the ISO 4049:2000 requirements. The final degradation values ranged between 1 and 5%, except for one of the formulations. Besides, some formulations showed bioactivity after seven days of immersion in SBF solution.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282012000400014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282012000400014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0104-14282012005000067
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Polímeros
publisher.none.fl_str_mv Associação Brasileira de Polímeros
dc.source.none.fl_str_mv Polímeros v.22 n.4 2012
reponame:Polímeros (São Carlos. Online)
instname:Associação Brasileira de Polímeros (ABPol)
instacron:ABPO
instname_str Associação Brasileira de Polímeros (ABPol)
instacron_str ABPO
institution ABPO
reponame_str Polímeros (São Carlos. Online)
collection Polímeros (São Carlos. Online)
repository.name.fl_str_mv Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)
repository.mail.fl_str_mv ||revista@abpol.org.br
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